Related references
Note: Only part of the references are listed.p53 regulates skeletal muscle mitophagy and mitochondrial quality control following denervation-induced muscle disuse
Jonathan M. Memme et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2022)
Impact of high-intensity interval training with or without l-citrulline on physical performance, skeletal muscle, and adipose tissue in obese older adults
Vincent Marcangeli et al.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2022)
Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults
Anurag Singh et al.
CELL REPORTS MEDICINE (2022)
Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of TBK1 to facilitate mitophagy
Beilei Gao et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2021)
Deubiquitinating enzyme USP30 negatively regulates mitophagy and accelerates myocardial cell senescence through antagonism of Parkin
Wei Pan et al.
CELL DEATH DISCOVERY (2021)
Parkin overexpression reduces inflammation-mediated cardiomyocyte apoptosis through activating Nrf2/ARE signaling pathway
Jianguo Bin et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2021)
The Lancet Global Health Commission on Global Eye Health: vision beyond 2020
Matthew J. Burton et al.
LANCET GLOBAL HEALTH (2021)
Global prevalence of osteoporosis among the world older adults: a comprehensive systematic review and meta-analysis
Nader Salari et al.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2021)
A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppression
Ekta Agarwal et al.
SCIENCE ADVANCES (2021)
Loss of Parkin contributes to mitochondrial turnover and dopaminergic neuronal loss in aged mice
Sachiko Noda et al.
NEUROBIOLOGY OF DISEASE (2020)
Nuclear Parkin Activates the ERR alpha Transcriptional Program and Drives Widespread Changes in Gene Expression Following Hypoxia
Sarah E. Shires et al.
SCIENTIFIC REPORTS (2020)
Parkin Overexpression Attenuates Sepsis-Induced Muscle Wasting
Jean-Philippe Leduc-Gaudet et al.
CELLS (2020)
A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling
Kahori Shiba-Fukushima et al.
ISCIENCE (2020)
Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling
Wei Zhang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Ageing as a risk factor for neurodegenerative disease
Yujun Hou et al.
NATURE REVIEWS NEUROLOGY (2019)
Parkin facilitates proteasome inhibitor-induced apoptosis via suppression of NF-κB activity in hepatocellular carcinoma
Xiaolan Zhang et al.
CELL DEATH & DISEASE (2019)
Regular Endurance Exercise Promotes Fission, Mitophagy, and Oxidative Phosphorylation in Human Skeletal Muscle Independently of Age
Estelle Balan et al.
FRONTIERS IN PHYSIOLOGY (2019)
Overexpression of pink1 or parkin in indirect flight muscles promotes mitochondrial proteostasis and extends lifespan in Drosophila melanogaster
Hongbin Si et al.
PLOS ONE (2019)
Parkin overexpression protects from ageing-related loss of muscle mass and strength
Jean-Philippe Leduc-Gaudet et al.
JOURNAL OF PHYSIOLOGY-LONDON (2019)
The Transcription Factor Function of Parkin: Breaking the Dogma
Cristine Alves da Costa et al.
FRONTIERS IN NEUROSCIENCE (2019)
Parkin does not prevent accelerated cardiac aging in mitochondria DNA mutator mice
Benjamin P. Woodall et al.
JCI INSIGHT (2019)
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans
Penelope A. Andreux et al.
NATURE METABOLISM (2019)
Monoamine oxidase-A is a novel driver of stress-induced premature senescence through inhibition of parkin-mediated mitophagy
Nicola Manzella et al.
AGING CELL (2018)
Loss of Parkin impairs mitochondrial function and leads to muscle atrophy
Nesibe Peker et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2018)
Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand
Thomas G. McWilliams et al.
CELL METABOLISM (2018)
PARKIN overexpression in human mesenchymal stromal cells from Wharton's jelly suppresses 6-hydroxydopamine-induced apoptosis: Potential therapeutic strategy in Parkinson's disease
A. R. Bonilla-Porras et al.
CYTOTHERAPY (2018)
Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin
Juliette J. Lee et al.
JOURNAL OF CELL BIOLOGY (2018)
Protective role of Parkin in skeletal muscle contractile and mitochondrial function
Gilles Gouspillou et al.
JOURNAL OF PHYSIOLOGY-LONDON (2018)
Senolytics improve physical function and increase lifespan in old age
Ming Xu et al.
NATURE MEDICINE (2018)
Overexpression of parkin protects retinal ganglion cells in experimental glaucoma
Yi Dai et al.
CELL DEATH & DISEASE (2018)
Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle
Chris Chin Wah Chen et al.
SKELETAL MUSCLE (2018)
Parkin and PINK1 mitigate STING-induced inflammation
Danielle A. Sliter et al.
NATURE (2018)
Phosphorylation of Parkin at serine 65 is essential for its activation in vivo
Thomas G. McWilliams et al.
OPEN BIOLOGY (2018)
Exercise and exercise training-induced increase in autophagy markers in human skeletal muscle
Nina Brandt et al.
PHYSIOLOGICAL REPORTS (2018)
Mitochondrial fission facilitates the selective mitophagy of protein aggregates
Jonathon L. Burman et al.
JOURNAL OF CELL BIOLOGY (2017)
Physical activity and healthy ageing: A systematic review and meta-analysis of longitudinal cohort studies
C. Daskalopoulou et al.
AGEING RESEARCH REVIEWS (2017)
PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease
Patricia Martin-Maestro et al.
HUMAN MOLECULAR GENETICS (2016)
Exercise Promotes Healthy Aging of Skeletal Muscle
Gregory D. Cartee et al.
CELL METABOLISM (2016)
Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system
Virgilio J. J. Cadete et al.
JOURNAL OF PHYSIOLOGY-LONDON (2016)
Urolithin A induces mitophagy and prolongs lifespan in C-elegans and increases muscle function in rodents
Dongryeol Ryu et al.
NATURE MEDICINE (2016)
Parkin structure and function
Marjan Seirafi et al.
FEBS JOURNAL (2015)
Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration
Daniel A. Stevens et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle
Gilles Gouspillou et al.
SCIENTIFIC REPORTS (2015)
Estrogen-related receptor alpha and mitochondria: tale of the titans
Harmit S. Ranhotra
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2015)
PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes
Dieter A. Kubli et al.
PLOS ONE (2015)
A new pathway for mitochondrial quality control: mitochondrial-derived vesicles
Ayumu Sugiura et al.
EMBO JOURNAL (2014)
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
Gian-Luca McLelland et al.
EMBO JOURNAL (2014)
Parkin overexpression ameliorates hippocampal long-term potentiation and β-amyloid load in an Alzheimer's disease mouse model
Xiaoqi Hong et al.
HUMAN MOLECULAR GENETICS (2014)
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
Lesley A. Kane et al.
JOURNAL OF CELL BIOLOGY (2014)
Long-Term Overexpression of Human Wild-Type and T240R Mutant Parkin in Rat Substantia Nigra Induces Progressive Dopaminergic Neurodegeneration
Anne-Sophie Van Rompuy et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2014)
Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
Alban Ordureau et al.
MOLECULAR CELL (2014)
Ubiquitin is phosphorylated by PINK1 to activate parkin
Fumika Koyano et al.
NATURE (2014)
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
Agne Kazlauskaite et al.
OPEN BIOLOGY (2014)
Protective role of PARK2/Parkin in sepsis-induced cardiac contractile and mitochondrial dysfunction
Jerome Piquereau et al.
AUTOPHAGY (2013)
Oxidative stress and mitochondrial dysfunction in glaucoma
Vicki Chrysostomou et al.
CURRENT OPINION IN PHARMACOLOGY (2013)
Structure of the human Parkin ligase domain in an autoinhibited state
Tobias Wauer et al.
EMBO JOURNAL (2013)
Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity
Bin Liu et al.
EXPERIMENTAL NEUROLOGY (2013)
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
Shireen A. Sarraf et al.
NATURE (2013)
Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
Anil Rana et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation
Jean-Francois Trempe et al.
SCIENCE (2013)
PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
Yun Chen et al.
SCIENCE (2013)
Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription
Eric Duplan et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2013)
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
B. E. Riley et al.
NATURE COMMUNICATIONS (2013)
Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart
Atsushi Hoshino et al.
NATURE COMMUNICATIONS (2013)
A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes
Vincent Soubannier et al.
CURRENT BIOLOGY (2012)
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
Andrew W. Greene et al.
EMBO REPORTS (2012)
Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo
Vincent Soubannier et al.
PLOS ONE (2012)
PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria
Kei Okatsu et al.
NATURE COMMUNICATIONS (2012)
Parkinson's Disease-Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria
Song Liu et al.
PLOS GENETICS (2012)
PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
Joo-Ho Shin et al.
CELL (2011)
PINK1 cleavage at position A103 by the mitochondrial protease PARL
Emma Deas et al.
HUMAN MOLECULAR GENETICS (2011)
The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons
Wendou Yu et al.
HUMAN MOLECULAR GENETICS (2011)
Parkin Ubiquitinates Drp1 for Proteasome-dependent Degradation IMPLICATION OF DYSREGULATED MITOCHONDRIAL DYNAMICS IN PARKINSON DISEASE
Hongxia Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
Liliane Glauser et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts
Aleksandar Rakovic et al.
PLOS ONE (2011)
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
Matthew E. Gegg et al.
HUMAN MOLECULAR GENETICS (2010)
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
Atsushi Tanaka et al.
JOURNAL OF CELL BIOLOGY (2010)
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
Seok Min Jin et al.
JOURNAL OF CELL BIOLOGY (2010)
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
Noriyuki Matsuda et al.
JOURNAL OF CELL BIOLOGY (2010)
Parkin Reverses Intracellular beta-Amyloid Accumulation and Its Negative Effects on Proteasome Function
Kenneth M. Rosen et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2010)
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Sven Geisler et al.
NATURE CELL BIOLOGY (2010)
The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway
Angela C. Poole et al.
PLOS ONE (2010)
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
Cristofol Vives-Bauza et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells
Der-Fen Suen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
Elena Ziviani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Parkinson's disease Insights from non-traditional model organisms
Ilse S. Pienaar et al.
PROGRESS IN NEUROBIOLOGY (2010)
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
Derek P. Narendra et al.
PLOS BIOLOGY (2010)
The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process
Jeehye Park et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Attenuation of doxorubicin-induced cardiac injury by mitochondrial glutaredoxin 2
Nicole M. Diotte et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Effects of partial suppression of parkin on huntingtin mutant R6/1 mice
Isabel Rubio et al.
BRAIN RESEARCH (2009)
Parkin promotes intracellular Aβ1-42 clearance
Mark P. Burns et al.
HUMAN MOLECULAR GENETICS (2009)
Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair
Oliver Rothfuss et al.
HUMAN MOLECULAR GENETICS (2009)
Identification of a Novel Zn2+-binding Domain in the Autosomal Recessive Juvenile Parkinson-related E3 Ligase Parkin
Ventzislava A. Hristova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease
Cristine Alves da Costa et al.
NATURE CELL BIOLOGY (2009)
Parkinson's disease-associated parkin colocalizes with Alzheimer's disease and multiple sclerosis brain lesions
Maarten E. Witte et al.
NEUROBIOLOGY OF DISEASE (2009)
DNA damage induces nuclear translocation of parkin
Shyan-Yuan Kao
JOURNAL OF BIOMEDICAL SCIENCE (2009)
Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers
Margaret Neuspiel et al.
CURRENT BIOLOGY (2008)
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek Narendra et al.
JOURNAL OF CELL BIOLOGY (2008)
The PINK1/Parkin pathway regulates mitochondrial morphology
Angela C. Poole et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
Hansong Deng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Mortality, oxidative stress and tau accumulation during ageing in parkin null mice
Jose A. Rodriguez-Navarro et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Parkin is an E3 ubiquitin-ligase for normal and mutant ataxin-2 and prevents ataxin-2-induced cell death
Duong P. Huynh et al.
EXPERIMENTAL NEUROLOGY (2007)
Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease
Linda Vercammen et al.
MOLECULAR THERAPY (2006)
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused inactivation of Drosophila Pink1 is rescued by by Parkin
Yufeng Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
Ira E. Clark et al.
NATURE (2006)
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
Jeehye Park et al.
NATURE (2006)
Parkin enhances mitochondrial biogenesis in proliferating cells
Y Kuroda et al.
HUMAN MOLECULAR GENETICS (2006)
Parkin counteracts symptoms in a Drosophila model of Parkinson's disease -: art. no. 14
AFM Haywood et al.
BMC NEUROSCIENCE (2004)
Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an α-synuclein rat model of Parkinson's disease
C Lo Bianco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Gene regulation and DNA damage in the ageing human brain
T Lu et al.
NATURE (2004)
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
Y Pesah et al.
DEVELOPMENT (2004)
RING finger 1 mutations in Parkin produce altered localization of the protein
MR Cookson et al.
HUMAN MOLECULAR GENETICS (2003)
Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27 (Publication with Expression of Concern. See vol. 114, 2017)
R Cesari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Parkin mutations and susceptibility alleles in late-onset Parkinson's disease
SA Oliveira et al.
ANNALS OF NEUROLOGY (2003)
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
JC Greene et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
F Darios et al.
HUMAN MOLECULAR GENETICS (2003)
Role of parkin mutations in 111 community-based patients with early-onset parkinsonism
M Kann et al.
ANNALS OF NEUROLOGY (2002)
Regulation of mitochondrial biogenesis in skeletal muscle by CaMK
H Wu et al.
SCIENCE (2002)
Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain
L Fallon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Parkin is associated with cellular vesicles
S Kubo et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Spatial distribution, cellular integration and stage development of Parkin protein in Xenopus brain
JM Horowitz et al.
DEVELOPMENTAL BRAIN RESEARCH (2001)
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
H Shimura et al.
NATURE GENETICS (2000)
Association between early-onset Parkinson's disease and mutations in the parkin gene
CB Lücking et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)