Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 87, Issue 15, Pages 10416-10421Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.2c00847
Keywords
-
Categories
Ask authors/readers for more resources
One-pot synthesis of siloles from readily available starting materials was proposed. This methodology allows for the preparation of multisubstituted siloles in good to excellent yields with complete regioselectivity. Sequential reactions, including lithiation, silylation, and diisobutylaluminum-hydride-promoted cyclization, enable the efficient formation of the siloles.
ABSTRACT: We propose one-pot synthesis of siloles from readily available starting materials. This methodology is practical for the preparation of multisubstituted siloles in good to excellent yields with complete regioselectivity. Sequential reactions, such as lithiation, silylation, and diisobutylaluminum-hydride-promoted cyclization, enable the preparation of the siloles. This transformation provides siloles through two efficient C-Si bond formations in one vessel.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available