4.7 Article

Transition-Metal-Free Domino Reaction of [60]Fullerene, Indole, and DMSO/HCl: One-Pot Access to Diverse N-Substituted [60]Fulleroindole Derivatives

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 87, Issue 12, Pages 7945-7954

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.2c00594

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Funding

  1. National Natural Science Foundation of China [51802001]
  2. Education Committee of Anhui Province [KJ2018A0037]

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An unprecedented multicomponent domino reaction of [60]fullerene, indole, and DMSO/HCl has been developed for the efficient one-pot synthesis of diverse N-substituted [60]fulleroindole derivatives. This method features simple operation, low cost, transition-metal-circumvented, and good functional group tolerance in indole.
An unprecedented multicomponent domino reaction of [60]fullerene, indole, and DMSO/HCl has been developed for the one-pot efficient synthesis of diverse N-substituted [60]fulleroindole derivatives. This methodology features simple operation, low cost, and transition-metal-circumvented and good functional group tolerance in indole.

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