4.5 Review

Machine learning in neuro-oncology: toward novel development fields

Journal

JOURNAL OF NEURO-ONCOLOGY
Volume 159, Issue 2, Pages 333-346

Publisher

SPRINGER
DOI: 10.1007/s11060-022-04068-7

Keywords

Artificial intelligence; Deep learning; Machine learning; Brain tumors; Central nervous system malignancies

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Artificial Intelligence (AI) has wide applications in neuro-oncology, including neuro-radiology, pathology, surgery, radiation therapy, and systemic treatments. AI can significantly reduce resources and costs while maintaining high quality standards in these fields.
Purpose Artificial Intelligence (AI) involves several and different techniques able to elaborate a large amount of data responding to a specific planned outcome. There are several possible applications of this technology in neuro-oncology. Methods We reviewed, according to PRISMA guidelines, available studies adopting AI in different fields of neuro-oncology including neuro-radiology, pathology, surgery, radiation therapy, and systemic treatments. Results Neuro-radiology presented the major number of studies assessing AI. However, this technology is being successfully tested also in other operative settings including surgery and radiation therapy. In this context, AI shows to significantly reduce resources and costs maintaining an elevated qualitative standard. Pathological diagnosis and development of novel systemic treatments are other two fields in which AI showed promising preliminary data. Conclusion It is likely that AI will be quickly included in some aspects of daily clinical practice. Possible applications of these techniques are impressive and cover all aspects of neuro-oncology.

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