4.7 Review

Calorie restriction and breast cancer treatment: a mini-review

Related references

Note: Only part of the references are listed.
Article Oncology

Cancer statistics, 2022

Rebecca L. Siegel et al.

Summary: Each year, the American Cancer Society compiles data on cancer occurrence and outcomes in the United States. The latest data shows that breast and prostate cancer progress has stagnated, while lung cancer has shown improvements in survival rates. Lung cancer incidence for advanced disease has declined while localized-stage rates have increased, resulting in higher survival rates. Mortality patterns align with incidence trends, with lung cancer deaths declining rapidly, breast cancer deaths slowing, and prostate cancer deaths stabilizing.

CA-A CANCER JOURNAL FOR CLINICIANS (2022)

Review Medicine, Research & Experimental

The ups and downs of caloric restriction and fasting: from molecular effects to clinical application

Sebastian J. Hofer et al.

Summary: Age-associated diseases are on the rise, leading to a need for efficient and low-cost methods. Caloric restriction (CR) is effective but implementation can be challenging, giving rise to CR-mimicking interventions. The advantages and disadvantages of these dietary interventions in humans must be carefully considered.

EMBO MOLECULAR MEDICINE (2022)

Review Biochemistry & Molecular Biology

The Potential Role of Spermine and Its Acetylated Derivative in Human Malignancies

Ryan Tsz-Hei Tse et al.

Summary: This article summarizes the roles of spermine in cancer development and its application as a diagnostic, prognostic, and therapeutic tool in various types of cancer.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Biotechnology & Applied Microbiology

Dynamics of breast tumor incidence, tumor volume and serum metabolic hormones in calorie restricted rats

Ece Koc Yildirim et al.

Summary: Research showed that a 50% calorie restriction after breast cancer development can effectively reduce tumor volume, with all tumors being benign in the CR-50% group. Serum adiponectin concentrations were higher in the calorie restriction group and alternate day feeding group compared to the cancer control group. The highest incidence of malignant and invasive tumors occurred in the cancer control group.

BIOTECHNIC & HISTOCHEMISTRY (2021)

Review Nutrition & Dietetics

A review of fasting effects on the response of cancer to chemotherapy

Mehdi Sadeghian et al.

Summary: Fasting may improve the response of tumor cells to chemotherapy through multiple mechanisms, protect normal cells, and enhance the effectiveness of chemotherapy. However, with limited human trials, more human studies with sufficient sample size and follow-ups are needed to confirm these findings.

CLINICAL NUTRITION (2021)

Article Oncology

The effect of caloric restriction and fasting on cancer

Mona Alidadi et al.

Summary: Caloric restriction (CR) and fasting have shown potential anticancer effects by reducing tumor progression, enhancing death of cancer cells, and elevating the effectiveness and tolerability of chemo- and radiotherapies. However, clinical studies on the potential of CR and fasting in cancer treatment are scarce and inconsistent, requiring further investigation to clarify their impact.

SEMINARS IN CANCER BIOLOGY (2021)

Article Oncology

Rationale and design of the Diet Restriction and Exercise-induced Adaptations in Metastatic breast cancer (DREAM) study: a 2-arm, parallel-group, phase II, randomized control trial of a short-term, calorie-restricted, and ketogenic diet plus exercise during intravenous chemotherapy versus usual care

Amy A. Kirkham et al.

Summary: The DREAM study will test a novel, short-term diet and exercise intervention that is targeted to mechanisms of tumor resistance to chemotherapy. A reduction in lesion size is likely to translate to improved cancer outcomes including disease progression and overall survival. Furthermore, a lifestyle intervention may empower patients with metastatic breast cancer by actively engaging them to play a key role in their treatment.

BMC CANCER (2021)

Review Medicine, Research & Experimental

Emerging roles of ATG7 in human health and disease

Jack J. Collier et al.

Summary: ATG proteins are essential for macroautophagy and play important roles beyond autophagic elimination. Dysfunction of ATG7 is associated with diseases, but the mechanisms of how it contributes to these diseases remain unclear. Further research on the relationship between ATG7 dysfunction and diseases will help develop therapies for disorders involving ATG7 deficiency and impaired autophagy.

EMBO MOLECULAR MEDICINE (2021)

Article Geriatrics & Gerontology

Fasting and fasting-mimicking diets for chemotherapy augmentation

Sebastian Brandhorst

Summary: The aging population in developed countries is likely to experience aging-related chronic diseases, including cancer. In addition to genetic and environmental factors, lifestyle choices play a crucial role in disease onset and progression.Studies show promising results for cancer patients and survivors using prolonged fasting and fasting-mimicking diets.

GEROSCIENCE (2021)

Review Oncology

Metabolic Reprogramming by Reduced Calorie Intake or Pharmacological Caloric Restriction Mimetics for Improved Cancer Immunotherapy

Erwan Eriau et al.

Summary: Reduced food intake and caloric restriction mimetics have been shown to increase healthy lifespan, reduce cancer incidence, and enhance responses to certain cancer treatments. These effects are mediated by cellular mechanisms and vary between cancer cells and healthy cells due to differences in metabolic requirements. Additionally, both reduced food intake and caloric restriction mimetics can induce autophagy, improving the efficacy of certain cancer treatments that induce immunogenic cell death and enhance the therapeutic efficacy of chemo-immunotherapies.

CANCERS (2021)

Review Oncology

Immune Checkpoint Inhibitors in Triple Negative Breast Cancer Treatment: Promising Future Prospects

Remy Thomas et al.

Summary: Immunotherapy, particularly immune checkpoint inhibitors, has revolutionized cancer treatment by leveraging a patient's own immune system to combat tumors. Triple negative breast cancer, as an immunogenic subtype, shows potential for positive responses to immunotherapy. Exploration of tumor characteristics and treatment strategies is crucial for enhancing the efficacy of immune checkpoint blockade in breast cancer treatment.

FRONTIERS IN ONCOLOGY (2021)

Review Oncology

Probiotics in Cancer

Ke Lu et al.

Summary: The consumption of over-the-counter probiotics has grown rapidly as an independent industry worldwide. Probiotics have been shown to improve the immune system and intestinal health, but may also cause adverse reactions in rare cases. Further research is needed to determine the benefits of probiotic management in cancer patients.

FRONTIERS IN ONCOLOGY (2021)

Review Geriatrics & Gerontology

Intermittent fasting: from calories to time restriction

Eleonora Duregon et al.

Summary: Calorie restriction (CR) is a dietary manipulation that can increase health and longevity, and recently, the length and periodicity of daily fasting have emerged as potential drivers behind beneficial health effects. Numerous strategies and eating patterns have been successfully developed to recapitulate the benefits of CR.

GEROSCIENCE (2021)

Review Medicine, General & Internal

Breast cancer

Sibylle Loibl et al.

Summary: Breast cancer diagnosis and treatment have become increasingly complex, incorporating various biomarkers and neoadjuvant therapies, with de-escalation schemes for radiotherapy now becoming standard practice.

LANCET (2021)

Review Oncology

Immune-related biomarkers in triple-negative breast cancer

Juan Zhang et al.

Summary: Breast cancer is a common female cancer worldwide, with triple-negative breast cancer being one of the most dangerous subtypes with high mortality and relapse rates. Immunotherapy has become a promising and effective treatment, but not all patients are sensitive to it, highlighting the importance of selecting suitable candidates for immunotherapy. Recent discoveries in immune-related factors of TNBC offer insights into predicting prognosis and response to immunotherapy.

BREAST CANCER (2021)

Review Pharmacology & Pharmacy

Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer

Chao Dong et al.

Summary: Hyperactivation of the PI3K/AKT/mTOR pathway is associated with drug resistance and cancer progression in breast cancer patients. Current research is focusing on developing drugs targeting this pathway to overcome acquired resistance to standard therapies.

FRONTIERS IN PHARMACOLOGY (2021)

Article Biochemistry & Molecular Biology

Characterising the Response of Human Breast Cancer Cells to Polyamine Modulation

Oluwaseun Akinyele et al.

Summary: Breast cancer is a complex disease with elevated polyamines contributing to disease progression. Different hormone receptor status breast cancer cells respond differently to polyamine modulation, with ER+ MCF-7 cells showing greater sensitivity to polyamine pathway inhibition. The antitumour effects of polyamine depletion in breast cancer cells may vary based on subtype, suggesting potential therapeutic benefits in targeting polyamine metabolism.

BIOMOLECULES (2021)

Review Biochemistry & Molecular Biology

A Review on Cancer Immunotherapy and Applications of Nanotechnology to Chemoimmunotherapy of Different Cancers

Safiye Akkin et al.

Summary: Variations in cancer treatment approaches exist globally, but cancer remains the second leading cause of death. Immunotherapy and nanotechnology may enhance the efficacy of cancer treatment.

MOLECULES (2021)

Article Oncology

Effects of caloric restriction on immunosurveillance, microbiota and cancer cell phenotype: Possible implications for cancer treatment

Francesca Pistollato et al.

Summary: Studies have shown that fasting, caloric restriction, and caloric restriction mimetics are associated with a lower risk of age-related diseases and a longer lifespan. These approaches have beneficial effects on cancer immunosurveillance, gut microbiota, metabolism, and cancer stem cell growth.

SEMINARS IN CANCER BIOLOGY (2021)

Review Nutrition & Dietetics

Possible Biochemical Processes Underlying the Positive Health Effects of Plant-Based Diets-A Narrative Review

Zoltan Szabo et al.

Summary: Plant-based diets are gaining popularity for their potential health benefits, such as disease prevention and improved biochemical processes. Nutrient-rich whole plant foods have positive physiological effects on health and may impact factors like insulin levels and signaling pathways. Further research is needed to explore the full potential of plant-based diets.

NUTRIENTS (2021)

Review Oncology

Breast Cancer-Epidemiology, Risk Factors, Classification, Prognostic Markers, and Current Treatment Strategies-An Updated Review

Sergiusz Lukasiewicz et al.

Summary: Breast cancer is the most commonly diagnosed cancer in women worldwide, with molecular subtypes providing new insights into treatment strategies and patient stratifications that impact the management of breast cancer patients.

CANCERS (2021)

Review Chemistry, Medicinal

Immunotherapy Treatment for Triple Negative Breast Cancer

Elizabeth R. Berger et al.

Summary: Triple-negative breast cancer (TNBC) is considered one of the highest-risk subtypes in breast cancer with dismal prognosis, lacking targeted therapy options. Immunotherapy, particularly immune checkpoint inhibitor therapy, has revolutionized the treatment landscape for TNBC, showing promising results.

PHARMACEUTICALS (2021)

Review Oncology

Breast Cancer Therapeutics and Biomarkers: Past, Present, and Future Approaches

Jason Schick et al.

Summary: Breast cancer is the leading cause of cancer death in women, with continual research leading to promising new treatments.

BREAST CANCER-BASIC AND CLINICAL RESEARCH (2021)

Review Oncology

Energy and caloric restriction, and fasting and cancer: a narrative review

Ezzeldin M. Ibrahim et al.

Summary: Dietary interventions have a significant impact on body metabolism and can hinder cancer growth and progression while enhancing the efficacy of chemotherapy and radiation therapy. Although current clinical trials have small sample sizes, they have shown clinical benefits for cancer patients.

SUPPORTIVE CARE IN CANCER (2021)

Article Oncology

Association Between Plasma Diacetylspermine and Tumor Spermine Synthase With Outcome in Triple-Negative Breast Cancer

Johannes F. Fahrmann et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2020)

Article Nutrition & Dietetics

Intermittent fasting 5:2 diet: What is the macronutrient and micronutrient intake and composition?

E. L. Scholtens et al.

CLINICAL NUTRITION (2020)

Review Oncology

The role of chemotherapy in treatment of advanced breast cancer: an overview for clinical practice

Anouk K. M. Claessens et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2020)

Article Cell Biology

Autophagy promotes mammalian survival by suppressing oxidative stress and p53

Yang Yang et al.

GENES & DEVELOPMENT (2020)

Review Oncology

Recent advances in radiotherapy of breast cancer

Jan Haussmann et al.

RADIATION ONCOLOGY (2020)

Review Oncology

PI(3,4)P2 Signaling in Cancer and Metabolism

Luca Gozzelino et al.

FRONTIERS IN ONCOLOGY (2020)

Review Biochemistry & Molecular Biology

Nutritional Aspects of Spermidine

Frank Madeo et al.

ANNUAL REVIEW OF NUTRITION, VOL 40, 2020 (2020)

Review Biotechnology & Applied Microbiology

Revisiting the Warburg Effect: Diet-Based Strategies for Cancer Prevention

Quangdon Tran et al.

BIOMED RESEARCH INTERNATIONAL (2020)

Review Multidisciplinary Sciences

Time-Restricted Eating: Benefits, Mechanisms, and Challenges in Translation

Prashant Regmi et al.

ISCIENCE (2020)

Review Biochemistry & Molecular Biology

The Molecular Link from Diet to Cancer Cell Metabolism

Shree Bose et al.

MOLECULAR CELL (2020)

Article Multidisciplinary Sciences

Fasting-mimicking diet and hormone therapy induce breast cancer regression

Irene Caffa et al.

NATURE (2020)

Review Biochemistry & Molecular Biology

Targeting Autophagy in Breast Cancer

Stefania Cocco et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Editorial Material Multidisciplinary Sciences

Fasting-mimicking diet plus chemotherapy in breast cancer treatment

Claudio Vernieri et al.

NATURE COMMUNICATIONS (2020)

Editorial Material Nutrition & Dietetics

Impacts of Calorie Restriction and Intermittent Fasting on Health and Diseases: Current Trends

Hae Young Chung et al.

NUTRIENTS (2020)

Review Oncology

The Double-Edge Sword of Autophagy in Cancer: From Tumor Suppression to Pro-tumor Activity

Rodolfo Chavez-Dominguez et al.

FRONTIERS IN ONCOLOGY (2020)

Review Nutrition & Dietetics

The Potential of Fasting and Caloric Restriction to Mitigate Radiation Damage-A Systematic Review

Simon Valayer et al.

FRONTIERS IN NUTRITION (2020)

Review Cell Biology

Time-restricted feeding (TRF) for prevention of age-related vascular cognitive impairment and dementia

Priya Balasubramanian et al.

AGEING RESEARCH REVIEWS (2020)

Review Oncology

Neoadjuvant Chemotherapy for Breast Cancer: Past, Present, and Future

Mariko Asaoka et al.

BREAST CANCER-BASIC AND CLINICAL RESEARCH (2020)

Review Cell Biology

Fasting to enhance Cancer treatment in models: the next steps

Jing Zhang et al.

JOURNAL OF BIOMEDICAL SCIENCE (2020)

Review Immunology

A guide to cancer immunotherapy: from T cell basic science to clinical practice

Alex D. Waldman et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Review Nutrition & Dietetics

Safety and Feasibility of Intermittent Fasting During Chemotherapy for Breast Cancer A Review of the Literature

Christine Lutes et al.

TOPICS IN CLINICAL NUTRITION (2020)

Editorial Material Oncology

Crizotinib - a tyrosine kinase inhibitor that stimulates immunogenic cell death

Peng Liu et al.

ONCOIMMUNOLOGY (2019)

Review Oncology

Targeting Autophagy in Cancer: Recent Advances and Future Directions

Ravi K. Amaravadi et al.

CANCER DISCOVERY (2019)

Article Medicine, General & Internal

Breast cancer

Nadia Harbeck et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

Review Biotechnology & Applied Microbiology

The Role Of PD-1/PD-L1 Axis In Treg Development And Function: Implications For Cancer Immunotherapy

Jiajing Cai et al.

ONCOTARGETS AND THERAPY (2019)

Review Nutrition & Dietetics

The Effects of Calorie Restriction on Autophagy: Role on Aging Intervention

Ki Wung Chung et al.

NUTRIENTS (2019)

Review Biochemistry & Molecular Biology

Protein restriction and cancer

Jie Yin et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2018)

Review Endocrinology & Metabolism

Molecular Actions of PPARα in Lipid Metabolism and Inflammation

Nadia Bougarne et al.

ENDOCRINE REVIEWS (2018)

Review Biochemistry & Molecular Biology

Molecular Signatures of the Insulin-Like Growth Factor 1-Mediated Epithelial-Mesenchymal Transition in Breast, Lung and Gastric Cancers

Armando Cevenini et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Medicine, General & Internal

Autophagy and intermittent fasting: the connection for cancer therapy?

Fernanda Antunes et al.

CLINICS (2018)

Review Endocrinology & Metabolism

High Levels of SIRT1 Expression as a Protective Mechanism Against Disease-Related Conditions

Birsen Elibol et al.

FRONTIERS IN ENDOCRINOLOGY (2018)

Review Biochemistry & Molecular Biology

Adenosine Monophosphate (AMP)-Activated Protein Kinase: A New Target for Nutraceutical Compounds

Fabiola Marin-Aguilar et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Multidisciplinary Sciences

Microenvironmental autophagy promotes tumour growth

Nadja S. Katheder et al.

NATURE (2017)

Review Biotechnology & Applied Microbiology

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

Lorenzo Galluzzi et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Review Cell Biology

Impact of intermittent fasting on health and disease processes

Mark P. Mattson et al.

AGEING RESEARCH REVIEWS (2017)

Review Oncology

Targeting autophagy in cancer

Jean M. Mulcahy Levy et al.

NATURE REVIEWS CANCER (2017)

Review Biochemistry & Molecular Biology

Caloric restriction - A promising anti-cancer approach: From molecular mechanisms to clinical trials

Gelina S. Kopeina et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2017)

Review Cell Biology

Recent insights into the function of autophagy in cancer

Ravi Amaravadi et al.

GENES & DEVELOPMENT (2016)

Article Biotechnology & Applied Microbiology

ATG7 promotes the tumorigenesis of lung cancer but might be dispensable for prognosis predication: a clinicopathologic study

Shaoxing Sun et al.

ONCOTARGETS AND THERAPY (2016)

Article Sport Sciences

No Effect of Caloric Restriction or Exercise on Radiation Repair Capacity

Nina Habermann et al.

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2015)

Review Oncology

Polyamines metabolism and breast cancer: state of the art and perspectives

Manuela Cervelli et al.

BREAST CANCER RESEARCH AND TREATMENT (2014)

Review Cell Biology

Fasting: Molecular Mechanisms and Clinical Applications

Valter D. Longo et al.

CELL METABOLISM (2014)

Review Biochemistry & Molecular Biology

The Function of Spermine

Anthony E. Pegg

IUBMB LIFE (2014)

Article Oncology

Mutational Landscape of the Essential Autophagy Gene BECN1 in Human Cancers

Saurabh V. Laddha et al.

MOLECULAR CANCER RESEARCH (2014)

Review Endocrinology & Metabolism

Protein and amino acid restriction, aging and disease: from yeast to humans

Hamed Mirzaei et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)

Article Cell Biology

Caloric restriction augments radiation efficacy in breast cancer

Anthony D. Saleh et al.

CELL CYCLE (2013)

Review Biochemistry & Molecular Biology

Caloric Restriction in Humans: Impact on Physiological, Psychological, and Behavioral Outcomes

Leanne M. Redman et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

Review Oncology

The Role of Autophagy in Cancer: Therapeutic Implications

Zhineng J. Yang et al.

MOLECULAR CANCER THERAPEUTICS (2011)

Review Oncology

The Double-Edged Sword of Autophagy Modulation in Cancer

Eileen White et al.

CLINICAL CANCER RESEARCH (2009)

Review Multidisciplinary Sciences

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

Matthew G. Vander Heiden et al.

SCIENCE (2009)