4.3 Article

Gingival metastasis from primary hepatocellular carcinoma: a case report

Journal

Publisher

SAGE PUBLICATIONS LTD
DOI: 10.1177/03000605221113408

Keywords

Hepatocellular carcinoma; mandibular metastasis; gingival metastasis; case report; hepatitis C virus; segmental mandibulectomy

Funding

  1. National Natural Science Foundation of China [31860321]

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We report a case of a patient with hepatocellular carcinoma who developed gingival metastasis after liver surgery. Treatment options, pathological results, and disease prognosis are discussed, and the importance of considering metastatic tumors in the differential diagnosis of mandibular gingival masses is emphasized.
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide; however, cases with metastasis to the oral cavity are extremely rare. Herein, we report a 68-year-old man who was diagnosed with HCC. Ten months after surgical removal of the right half of his liver, the patient developed gingival metastasis. Unfortunately, the patient died 4 months after the diagnosis. We discuss treatment options, pathological results, and disease prognosis. When a mandibular gingival mass is found, metastatic tumors should be considered in the differential diagnosis. In this regard, the patient's medical history and physical examination are valuable indicators for the diagnosis of mandibular gingival metastasis. This case provides a basis for the clinical diagnosis of metastatic HCC involving the oral cavity.

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