Related references
Note: Only part of the references are listed.Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control
Hannah P. Gideon et al.
IMMUNITY (2022)
Lysosomal gene Hexb displays haploinsufficiency in a knock-in mouse model of Alzheimer's disease
Lauren S. Whyte et al.
IBRO NEUROSCIENCE REPORTS (2022)
Schistosoma mansoni Eggs Modulate the Timing of Granuloma Formation to Promote Transmission
Kevin K. Takaki et al.
CELL HOST & MICROBE (2021)
Microglia and Central Nervous System-Associated Macrophages-From Origin to Disease Modulation
Marco Prinz et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 39 (2021)
Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease prevention
Kevin D. Rynearson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2021)
A non-canonical type 2 immune response coordinates tuberculous granuloma formation and epithelialization
Mark R. Cronan et al.
CELL (2021)
Microglia use TAM receptors to detect and engulf amyloid β plaques
Youtong Huang et al.
NATURE IMMUNOLOGY (2021)
US FDA defends approval of Alzheimer's disease drug
Susan Jaffe
LANCET (2021)
Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer's disease
Christel Claes et al.
MOLECULAR NEURODEGENERATION (2021)
Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer's disease
Samuel Morabito et al.
NATURE GENETICS (2021)
FDA approval for Biogen's aducanumab sparks Alzheimer disease firestorm
Asher Mullard
NATURE REVIEWS DRUG DISCOVERY (2021)
Controversy and Progress in Alzheimer's Disease - FDA Approval of Aducanumab
Gil D. Rabinovici
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Endosomal dysfunction impacts extracellular vesicle release: Central role in Aβ pathology
B. D. Arbo et al.
AGEING RESEARCH REVIEWS (2020)
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease
Yingyue Zhou et al.
NATURE MEDICINE (2020)
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Julia Marschallinger et al.
NATURE NEUROSCIENCE (2020)
Cerebral amyloid angiopathy and Alzheimer disease - one peptide, two pathways
Steven M. Greenberg et al.
NATURE REVIEWS NEUROLOGY (2020)
Mycobacterium tuberculosis pathogenicity viewed through the lens of molecular Koch's postulates
Lalita Ramakrishnan
CURRENT OPINION IN MICROBIOLOGY (2020)
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease
Ethan R. Roy et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Amyloid-β oligomers in cellular models of Alzheimer's disease
Igor C. Fontana et al.
JOURNAL OF NEUROCHEMISTRY (2020)
Microglia depletion rapidly and reversibly alters amyloid pathology by modification of plaque compaction and morphologies
Brad T. Casali et al.
NEUROBIOLOGY OF DISEASE (2020)
Mycobacterium tuberculosis Infection-Driven Foamy Macrophages and Their Implications in Tuberculosis Control as Targets for Host-Directed Therapy (vol 11, 910, 2020)
Dahee Shim et al.
FRONTIERS IN IMMUNOLOGY (2020)
Novel Hexb-based tools for studying microglia in the CNS
Takahiro Masuda et al.
NATURE IMMUNOLOGY (2020)
siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice
Wei Tao et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans
Nicola Thrupp et al.
CELL REPORTS (2020)
The Complexity of Microglial Interactions With Innate and Adaptive Immune Cells in Alzheimer's Disease
Season K. Wyatt-Johnson et al.
FRONTIERS IN AGING NEUROSCIENCE (2020)
The relationship between the morphological subtypes of microglia and Alzheimer's disease neuropathology
Patrick Jarmo Paasila et al.
BRAIN PATHOLOGY (2019)
A Close Look at BACE1 Inhibitors for Alzheimer's Disease Treatment
Brati Das et al.
CNS DRUGS (2019)
Sequential formation of different layers of dystrophic neurites in Alzheimer's brains
Md Golam Sharoar et al.
MOLECULAR PSYCHIATRY (2019)
Single-cell transcriptomic analysis of Alzheimer's disease
Hansruedi Mathys et al.
NATURE (2019)
Microglia in Brain Development, Homeostasis, and Neurodegeneration
Christopher J. Bohlen et al.
Annual Review of Genetics (2019)
The neuropathological diagnosis of Alzheimer's disease
Michael A. DeTure et al.
MOLECULAR NEURODEGENERATION (2019)
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
Justin M. Long et al.
CELL (2019)
A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation
Alexandra Grubman et al.
NATURE NEUROSCIENCE (2019)
Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model
Elizabeth Spangenberg et al.
NATURE COMMUNICATIONS (2019)
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Iris E. Jansen et al.
NATURE GENETICS (2019)
Genetic variation within endolysosomal system is associated with late-onset Alzheimer's disease
Song Gao et al.
BRAIN (2018)
The interstitial macrophage: A long-neglected piece in the puzzle of lung immunity
Maude Liegeois et al.
CELLULAR IMMUNOLOGY (2018)
Cutaneous Granulomatosis: a Comprehensive Review
Benedetta Terziroli Beretta-Piccoli et al.
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2018)
Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny
Lu Huang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
The Formation and Function of Granulomas
Antonio J. Pagan et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 36 (2018)
Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination
Sara B. Cohen et al.
CELL HOST & MICROBE (2018)
TREM2-a key player in microglial biology and Alzheimer disease
Tyler K. Ulland et al.
NATURE REVIEWS NEUROLOGY (2018)
Epitomic Characterization of the Specificity of the Anti-Amyloid A beta Monoclonal Antibodies 6E10 and 4G8
Ibtisam Baghallab et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Microglia and macrophages in brain homeostasis and disease
Qingyun Li et al.
NATURE REVIEWS IMMUNOLOGY (2018)
Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease
Ralph A. Nixon
FASEB JOURNAL (2017)
Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?
Lauren S. Whyte et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Immune hyperreactivity of Ab plaque-associated microglia in Alzheimer's disease
Zhuoran Yin et al.
NEUROBIOLOGY OF AGING (2017)
RTN1 and RTN3 protein are differentially associated with senile plaques in Alzheimer's brains
Qi Shi et al.
SCIENTIFIC REPORTS (2017)
Heterogeneity in tuberculosis
Anthony M. Cadena et al.
NATURE REVIEWS IMMUNOLOGY (2017)
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Hadas Keren-Shaul et al.
CELL (2017)
Is amyloid-beta harmful to the brain? Insights from human imaging studies
William Jagust
BRAIN (2016)
Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology
Adrian Olmos-Alonso et al.
BRAIN (2016)
The amyloid hypothesis of Alzheimer's disease at 25years
Dennis J. Selkoe et al.
EMBO MOLECULAR MEDICINE (2016)
Microglia Contributes to Plaque Growth by Cell Death Due to Uptake of Amyloid β in the Brain of Alzheimer's Disease Mouse Model
Sung Hoon Baik et al.
GLIA (2016)
TAM receptors regulate multiple features of microglial physiology
Lawrence Fourgeaud et al.
NATURE (2016)
The antibody aducanumab reduces Aβ plaques in Alzheimer's disease
Jeff Sevigny et al.
NATURE (2016)
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy (vol 90, pg 724, 2016)
Peng Yuan et al.
NEURON (2016)
The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function
Samuel E. Marsh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke
Gergely Szalay et al.
NATURE COMMUNICATIONS (2016)
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer's Disease Model
Yaming Wang et al.
CELL (2015)
Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice
Nabil N. Dagher et al.
JOURNAL OF NEUROINFLAMMATION (2015)
Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease
Julie C. Savage et al.
JOURNAL OF NEUROSCIENCE (2015)
Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
Carlo Condello et al.
NATURE COMMUNICATIONS (2015)
Targeting Prodromal Alzheimer Disease With Avagacestat A Randomized Clinical Trial
Vladimir Coric et al.
JAMA NEUROLOGY (2015)
Neuropathology and biochemistry of Aβ and its aggregates in Alzheimer's disease
Dietmar Rudolf Thal et al.
ACTA NEUROPATHOLOGICA (2015)
Immunity and Immunopathology in the Tuberculous Granuloma
Antonio J. Pagan et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2015)
Host Evasion and Exploitation Schemes of Mycobacterium tuberculosis
C. J. Cambier et al.
CELL (2014)
Genetic Heterogeneity in Alzheimer Disease and Implications for Treatment Strategies
John M. Ringman et al.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2014)
T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases
Hugo Gonzalez et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Single App knock-in mouse models of Alzheimer's disease
Takashi Saito et al.
NATURE NEUROSCIENCE (2014)
Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
Monica R. P. Elmore et al.
NEURON (2014)
Fluorine-18 Radiolabeled Heterocycles as PET Tracers for Imaging β-Amyloid Plaques in Alzheimer's Disease
Fanxing Zeng et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)
Amyloid-β Positron Emission Tomography Imaging Probes: A Critical Review
Vladimir Kepe et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2013)
Biology of the TAM Receptors
Greg Lemke
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis
Ida Annunziata et al.
NATURE COMMUNICATIONS (2013)
Correlation of Amyloid PET Ligand Florbetapir F 18 Binding With Aβ Aggregation and Neuritic Plaque Deposition in Postmortem Brain Tissue
Seok Rye Choi et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2012)
Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia
Hongjun Fu et al.
GLIA (2012)
Lysosomal storage disorders: The cellular impact of lysosomal dysfunction
Frances M. Platt et al.
JOURNAL OF CELL BIOLOGY (2012)
Lysosomal Dysfunction in a Mouse Model of Sandhoff Disease Leads to Accumulation of Ganglioside-Bound Amyloid-β Peptide
Serene Keilani et al.
JOURNAL OF NEUROSCIENCE (2012)
Revisiting the role of the granuloma in tuberculosis
Lalita Ramakrishnan
NATURE REVIEWS IMMUNOLOGY (2012)
Amyloid Precursor Protein Processing and Alzheimer's Disease
Richard J. O'Brien et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 (2011)
Linking lipids to Alzheimer's disease: cholesterol and beyond
Gilbert Di Paolo et al.
NATURE REVIEWS NEUROSCIENCE (2011)
Neuropathological Alterations in Alzheimer Disease
Alberto Serrano-Pozo et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2011)
Amyloid oligomers: formation and toxicity of A beta oligomers
Masafumi Sakono et al.
FEBS JOURNAL (2010)
Cell-Mediated Immune Responses in Tuberculosis
Andrea M. Cooper
ANNUAL REVIEW OF IMMUNOLOGY (2009)
The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection
J. Muse Davis et al.
CELL (2009)
Astroglia in dementia and Alzheimer's disease
J. J. Rodriguez et al.
CELL DEATH AND DIFFERENTIATION (2009)
Macrophage heterogeneity in atherosclerotic plaques
Jason L. Johnson et al.
CURRENT OPINION IN LIPIDOLOGY (2009)
Preclinical Properties of 18F-AV-45: A PET Agent for Aβ Plaques in the Brain
Seok Rye Choi et al.
JOURNAL OF NUCLEAR MEDICINE (2009)
Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin
Karel Otero et al.
NATURE IMMUNOLOGY (2009)
Foamy macrophages and the progression of the human tuberculosis granuloma
David G. Russell et al.
NATURE IMMUNOLOGY (2009)
Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia
Stefan A. Grathwohl et al.
NATURE NEUROSCIENCE (2009)
Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide
Xiaoyan Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Foreign body reaction to biomaterials
James M. Anderson et al.
SEMINARS IN IMMUNOLOGY (2008)
Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations:: Potential factors in amyloid plaque formation
Holly Oakley et al.
JOURNAL OF NEUROSCIENCE (2006)
Aβ42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
Rebecca Radde et al.
EMBO REPORTS (2006)
Neuropathology of older persons without cognitive impairment from two community-based studies
D. A. Bennett et al.
NEUROLOGY (2006)
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
A Nimmerjahn et al.
SCIENCE (2005)
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
WE Klunk et al.
ANNALS OF NEUROLOGY (2004)
Cell biology of Mycobacterium tuberculosis phagosome
I Vergne et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2004)
Amyloid binding ligands as Alzheimer's disease therapies
VMY Lee
NEUROBIOLOGY OF AGING (2002)
Imaging Aβ plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative
WE Klunk et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)
Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APPsw mice
T Mori et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)
Alzheimer's disease: Genes, proteins, and therapy
DJ Selkoe
PHYSIOLOGICAL REVIEWS (2001)