Solubility Determination and Thermodynamic Modeling of Methanesulfonamide in 13 Pure Solvents at Temperatures of 283.15-323.15 K

In this paper, the solubility of methanesulfonamide (MSAM) in selected 13 pure solvents including 9 alcohols (methanol, ethanol, n-propanol, iso-propanol, n-butanol, sec-butanol, iso-butanol, n-pentanol, and iso-pentanol) and 4 esters (ethyl acetate, propyl acetate, iso-propyl acetate, and methyl propionate) at atmospheric pressure and temperatures from 283.15 to 323.15 K was determined. The solubility as a function of temperature was regressed using modified Apelblat, Van't Hoff, lambda h, Wilson, and nonrandom two-liquid (NRTL) models. Based on the experimental and the simulation results, the thermodynamic mixing properties of the solutions, mixing Gibbs energy, enthalpy, and entropy were evaluated.

Automated summary

This paper investigates the solubility of methanesulfonamide (MSAM) in 13 selected pure solvents, and regression analysis is performed to determine the relationship between solubility and temperature. The thermodynamic mixing properties of the solutions are evaluated based on experimental and simulation results.