4.7 Article

Autophagy blockade potentiates cancer-associated immunosuppression through programmed death ligand-1 upregulation in bladder cancer

Related references

Note: Only part of the references are listed.
Review Oncology

Regulation of PD-L1 expression in the tumor microenvironment

Ming Yi et al.

Summary: PD-L1 expression is regulated by various factors, impacting the treatment effect and patient selection. Understanding the mechanisms of PD-L1 regulation helps enhance the efficacy of immunotherapy.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)

Article Oncology

MicroRNA-34a-5p serves as a tumor suppressor by regulating the cell motility of bladder cancer cells through matrix metalloproteinase-2 silencing

Kuang-Yu Chou et al.

Summary: hsa-miR-34a plays a role in inhibiting cell migration and invasion in bladder cancer by silencing matrix metalloproteinase-2 (MMP-2) expression, thus interrupting MMP-2-mediated cell motility.

ONCOLOGY REPORTS (2021)

Review Oncology

Immune Checkpoint Inhibitors for the Treatment of Bladder Cancer

Antonio Lopez-Beltran et al.

Summary: Several immune checkpoint inhibitors have been approved for the treatment of patients with metastatic urothelial carcinoma, showing promising efficacy in first-line or second-line therapy. PD-L1 expression may be a predictive factor for response to ICIs. Anti-PD-1 and PD-L1 antibodies have demonstrated durable responses in some mUC patients.

CANCERS (2021)

Article Environmental Sciences

Attenuation of chloroquine and hydroxychloroquine on the invasive potential of bladder cancer through targeting matrix metalloproteinase 2 expression

Kuang-Yu Chou et al.

Summary: The study demonstrated that chloroquine and hydroxychloroquine inhibit the migration and invasion of bladder cancer cells by modulating the expression of matrix metalloproteinase-2, and this effect is based on autophagy inhibition.

ENVIRONMENTAL TOXICOLOGY (2021)

Review Urology & Nephrology

The global burden of urinary bladder cancer: an update

Anke Richters et al.

WORLD JOURNAL OF UROLOGY (2020)

Article Multidisciplinary Sciences

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

Keisuke Yamamoto et al.

NATURE (2020)

Article Medicine, Research & Experimental

PD-L1 expression in liver metastasis: its clinical significance and discordance with primary tumor in colorectal cancer

Xiao-Li Wei et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2020)

Review Oncology

The Role of Autophagy in Tumor Immunology-Complex Mechanisms That May Be Explored Therapeutically

Alana Serrano Campelo de Souza et al.

FRONTIERS IN ONCOLOGY (2020)

Review Biochemistry & Molecular Biology

Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications

Francesca Nazio et al.

CELL DEATH AND DIFFERENTIATION (2019)

Article Oncology

Autophagy inhibition enhances PD-L1 expression in gastric cancer

Xiaojuan Wang et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Review Oncology

MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer

Lu Zhang et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Article Oncology

Cancer statistics, 2019

Rebecca L. Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2019)

Article Cell Biology

CCN2 promotes drug resistance in osteosarcoma by enhancing ABCG2 expression

Hsiao-Chi Tsai et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Review Biochemistry & Molecular Biology

The Roles of Autophagy in Cancer

Chul Won Yun et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Biochemistry & Molecular Biology

Autophagy in cancer metastasis

E. E. Mowers et al.

ONCOGENE (2017)

Article Medicine, Research & Experimental

Chloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosis

Yi-Chia Lin et al.

KAOHSIUNG JOURNAL OF MEDICAL SCIENCES (2017)

Review Oncology

De-novo and acquired resistance to immune checkpoint targeting

Nicholas L. Syn et al.

LANCET ONCOLOGY (2017)

Article Chemistry, Medicinal

Cisplatin induces protective autophagy through activation of BECNI in human bladder cancer cells

Ji-Fan Lin et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2017)

Article Urology & Nephrology

Inhibition of High Basal Level of Autophagy Induces Apoptosis in Human Bladder Cancer Cells

Yi-Chia Lin et al.

JOURNAL OF UROLOGY (2016)

Review Oncology

Predictive biomarkers for checkpoint inhibitor-based immunotherapy

Geoffrey T. Gibney et al.

LANCET ONCOLOGY (2016)

Article Oncology

Autophagy Inhibition Dysregulates TBK1 Signaling and Promotes Pancreatic Inflammation

Shenghong Yang et al.

CANCER IMMUNOLOGY RESEARCH (2016)

Review Biochemistry & Molecular Biology

The role of MicroRNAs in human cancer

Yong Peng et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2016)

Article Pharmacology & Pharmacy

PD-1/PD-L1 inhibitors

Joel Sunshine et al.

CURRENT OPINION IN PHARMACOLOGY (2015)

Review Immunology

Autophagy in inflammation, infection, neurodegeneration and cancer

Daniela S. Arroyo et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2014)

Editorial Material Multidisciplinary Sciences

Cancer Immunotherapy

Marcia McNutt

SCIENCE (2013)

Article Oncology

Cancer Statistics, 2012

Rebecca Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2012)

Article Cell Biology

Inhibition of autophagy impairs tumor cell invasion in an organotypic model

Robin L. Macintosh et al.

CELL CYCLE (2012)

Review Oncology

Autophagy: cellular and molecular mechanisms

Danielle Glick et al.

JOURNAL OF PATHOLOGY (2010)