☆ 4.7 Article

Mechanistic insight into premature atherosclerosis and cardiovascular complications in systemic lupus erythematosus

JOURNAL OF AUTOIMMUNITY (2022)

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Increased visceral adipose tissue and altered adiposity distribution in premenopausal lupus patients: correlation with cardiovascular risk factors

L. P. C. Seguro et al.

LUPUS (2018)

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Atherogenic dyslipidemia promotes autoimmune follicular helper T cell responses via IL-27

Heeju Ryu et al.

NATURE IMMUNOLOGY (2018)

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The non-haemostatic role of platelets in systemic lupus erythematosus

Petrus Linge et al.

NATURE REVIEWS RHEUMATOLOGY (2018)

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Disease trends over time and CD4+CCR5+ T-cells expansion predict carotid atherosclerosis development in patients with systemic lupus erythematosus

A. Baragetti et al.

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2018)

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Myeloid-Specific Deletion of Peptidylarginine Deiminase 4 Mitigates Atherosclerosis

Yudong Liu et al.

FRONTIERS IN IMMUNOLOGY (2018)

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Elevation of serum proprotein convertase subtilisin/kexin type 9 (PCSK9) concentrations and its possible atherogenic role in patients with systemic lupus erythematosus

Chenglong Fang et al.

ANNALS OF TRANSLATIONAL MEDICINE (2018)

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QRISK3 improves detection of cardiovascular disease risk in patients with systemic lupus erythematosus

Nicola Edwards et al.

LUPUS SCIENCE & MEDICINE (2018)

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Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus

Philip M. Carlucci et al.

JCI INSIGHT (2018)

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Lupus high-density lipoprotein induces proinflammatory responses in macrophages by binding lectin-like oxidised low-density lipoprotein receptor 1 and failing to promote activating transcription factor 3 activity

Carolyne K. Smith et al.

ANNALS OF THE RHEUMATIC DISEASES (2017)

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Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction

Yasuko Furumoto et al.

ARTHRITIS & RHEUMATOLOGY (2017)

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Dyslipidemia in systemic lupus erythematosus

Melinda Zsuzsanna Szabo et al.

IMMUNOLOGIC RESEARCH (2017)

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IFN-α Negatively Regulates the Expression of Endothelial Nitric Oxide Synthase and Nitric Oxide Production: Implications for Systemic Lupus Erythematosus

Joy Jones Buie et al.

JOURNAL OF IMMUNOLOGY (2017)

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Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9

Jillian P. Rhoads et al.

JOURNAL OF IMMUNOLOGY (2017)

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Longterm Hydroxychloroquine Therapy and Low-dose Aspirin May Have an Additive Effectiveness in the Primary Prevention of Cardiovascular Events in Patients with Systemic Lupus Erythematosus

Serena Fasano et al.

JOURNAL OF RHEUMATOLOGY (2017)

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LOX-1 in Atherosclerosis and Myocardial Ischemia Biology, Genetics, and Modulation

Naga Venkata K. Pothineni et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2017)

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IRF3 and type I interferons fuel a fatal response to myocardial infarction

Kevin R. King et al.

NATURE MEDICINE (2017)

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Effect of long-term hydroxychloroquine on vascular events in patients with systemic lupus erythematosus: a database prospective cohort study

Chung-Yuan Hsu et al.

RHEUMATOLOGY (2017)

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Serum Levels of Anti-PON1 and Anti-HDL Antibodies as Potential Biomarkers of Premature Atherosclerosis in Systemic Lupus Erythematosus

Patricia Lopez et al.

THROMBOSIS AND HAEMOSTASIS (2017)

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Risk of Myocardial Infarction and Stroke in Newly Diagnosed Systemic Lupus Erythematosus: A General Population-Based Study

J. Antonio Avina-Zubieta et al.

ARTHRITIS CARE & RESEARCH (2017)

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The gut microbiome in atherosclerotic cardiovascular disease

Zhuye Jie et al.

NATURE COMMUNICATIONS (2017)

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Race/Ethnicity and Cardiovascular Events Among Patients With Systemic Lupus Erythematosus

Medha Barbhaiya et al.

ARTHRITIS & RHEUMATOLOGY (2017)

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Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus

Richard Furie et al.

ARTHRITIS & RHEUMATOLOGY (2017)

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Excess atherosclerosis in systemic lupus erythematosus,-A matter of renal involvement: Case control study of 281 SLE patients and 281 individually matched population controls

Johanna T. Gustafsson et al.

PLOS ONE (2017)

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Cardiovascular risk profiles in a lupus cohort: what do different calculators tell us?

Daniel Boulos et al.

LUPUS SCIENCE & MEDICINE (2017)

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Osteopontin is associated with disease severity and antiphospholipid syndrome in well characterised Swedish cases of SLE

Lina Wirestam et al.

LUPUS SCIENCE & MEDICINE (2017)

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Pattern of risks of systemic lupus erythematosus among statin users: a population-based cohort study

Hilda J. I. De Jong et al.

ANNALS OF THE RHEUMATIC DISEASES (2017)

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Stroke in systemic lupus erythematosus: a Swedish population-based cohort study

Elizabeth V. Arkema et al.

ANNALS OF THE RHEUMATIC DISEASES (2017)

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High-sensitivity cardiac troponin T is a biomarker for atherosclerosis in systemic lupus erythematous patients: a crosssectional controlled study

Gillian Divard et al.

ARTHRITIS RESEARCH & THERAPY (2017)

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Association of aortic perivascular adipose tissue density with aortic calcification in women with systemic lupus erythematosus

Kelly J. Shields et al.

ATHEROSCLEROSIS (2017)

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Neutrophil Extracellular Traps Drive Endothelial-to-Mesenchymal Transition

Elmar Pieterse et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)

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Activated Platelets Induce Endothelial Cell Activation via an Interleukin-1 Pathway in Systemic Lupus Erythematosus

Sokha Nhek et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)

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Effects of Long-Term Type I Interferon on the Arterial Wall and Smooth Muscle Progenitor Cells Differentiation

Yanpeng Diao et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)

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Senescent profile of angiogenic T cells from systemic lupus erythematosus patients

Patricia Lopez et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2016)

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Metabolic syndrome is associated with decreased circulating endothelial progenitor cells and increased arterial stiffness in systemic lupus erythematosus

R. Castejon et al.

LUPUS (2016)

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Sifalimumab, an anti-interferon-α monoclonal antibody, in moderate to severe systemic lupus erythematosus: a randomised, double-blind, placebo-controlled study

Munther Khamashta et al.

ANNALS OF THE RHEUMATIC DISEASES (2016)

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CCR5+T-bet+FoxP3+ Effector CD4 T Cells Drive Atherosclerosis

Jie Li et al.

CIRCULATION RESEARCH (2016)

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IgM antibodies against malondialdehyde and phosphorylcholine are together strong protection markers for atherosclerosis in systemic lupus erythematosus: Regulation and underlying mechanisms

Mizanur Rahman et al.

CLINICAL IMMUNOLOGY (2016)

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Modified Framingham Risk Factor Score for Systemic Lupus Erythematosus

Murray B. Urowitz et al.

JOURNAL OF RHEUMATOLOGY (2016)

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Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus

Jing He et al.

NATURE MEDICINE (2016)

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Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

Christian Lood et al.

NATURE MEDICINE (2016)

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Brief Report: Trends in Hospitalizations Due to Acute Coronary Syndromes and Stroke in Patients With Systemic Lupus Erythematosus, 1996 to 2012

Maria G. Tektonidou et al.

ARTHRITIS & RHEUMATOLOGY (2016)

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Vitamin D Deficiency Is Associated With Endothelial Dysfunction and Increases Type I Interferon Gene Expression in a Murine Model of Systemic Lupus Erythematosus

John A. Reynolds et al.

Arthritis & Rheumatology (2016)

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Dynamics of pulse wave velocity and vascular augmentation index in association with endothelial progenitor cells in SLE

Peter Korsten et al.

LUPUS SCIENCE & MEDICINE (2016)

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Cross-talk between iNKT cells and monocytes triggers an atheroprotective immune response in SLE patients with asymptomatic plaque

Edward Smith et al.

SCIENCE IMMUNOLOGY (2016)

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Statin reduces mortality and morbidity in systemic lupus erythematosus patients with hyperlipidemia: A nationwide population-based cohort study

Hsin-Hui Yu et al.

ATHEROSCLEROSIS (2015)

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How HDL protects LDL against atherogenic modification: paraoxonase 1 and other dramatis personae

Handrean Soran et al.

CURRENT OPINION IN LIPIDOLOGY (2015)

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CD4+CXCR3+T cells and plasmacytoid dendritic cells drive accelerated atherosclerosis associated with systemic lupus erythematosus

Marc Clement et al.

JOURNAL OF AUTOIMMUNITY (2015)

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Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

Annika Warnatsch et al.

SCIENCE (2015)

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Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice

Jason S. Knight et al.

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Dysregulated CD4+ T cells from SLE-susceptible mice are sufficient to accelerate atherosclerosis in LDLr-/- mice

Ashley J. Wilhelm et al.

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Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2

Carmelo Carmona-Rivera et al.

ANNALS OF THE RHEUMATIC DISEASES (2015)

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Interleukin 10 hampers endothelial cell differentiation and enhances the effects of interferon α on lupus endothelial cell progenitors

Alyssa M. Cates et al.

RHEUMATOLOGY (2015)

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Impaired serum cholesterol efflux capacity in rheumatoid arthritis and systemic lupus erythematosus

Nicoletta Ronda et al.

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Subclinical Atherosclerosis in Systemic Lupus Erythematosus and Antiphospholipid Syndrome Focus on β2GPI-Specific T Cell Response

Fabrizio Conti et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2014)

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Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis

Jason S. Knight et al.

CIRCULATION RESEARCH (2014)

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The association of serum parathyroid hormone and severity of coronary artery diseases

Shadi Shekarkhar et al.

CORONARY ARTERY DISEASE (2014)

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Peroxisome proliferator-activated receptor gamma agonists in the prevention and treatment of murine systemic lupus erythematosus

Tamar R. Aprahamian et al.

IMMUNOLOGY (2014)

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Involvement of TLR4 in Oxidized LDL/β2GPI/Anti-β2GPI-Induced Transformation of Macrophages to Foam Cells

Xiaolei Zhang et al.

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2014)

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oxLDL/β2GPI/anti-β2GPI complex induced macrophage differentiation to foam cell involving TLR4/NF-kappa B signal transduction pathway

Ya Xu et al.

THROMBOSIS RESEARCH (2014)

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A Panel of Biomarkers Is Associated With Increased Risk of the Presence and Progression of Atherosclerosis in Women With Systemic Lupus Erythematosus

Maureen McMahon et al.

ARTHRITIS & RHEUMATOLOGY (2014)

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Neutrophil Extracellular Trap-Derived Enzymes Oxidize High-Density Lipoprotein An Additional Proatherogenic Mechanism in Systemic Lupus Erythematosus

Carolyne K. Smith et al.

ARTHRITIS & RHEUMATOLOGY (2014)

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Coronary Heart Disease in Systemic Lupus Erythematosus Is Associated With Interferon Regulatory Factor-8 Gene Variants

Dag Leonard et al.

CIRCULATION-CARDIOVASCULAR GENETICS (2013)

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Th17/Treg imbalance induced by increased incidence of atherosclerosis in patients with Systemic Lupus Erythematosus (SLE)

Zhu Mengya et al.

CLINICAL RHEUMATOLOGY (2013)

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Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus

Jason S. Knight et al.

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BAFF Receptor mAb Treatment Ameliorates Development and Progression of Atherosclerosis in Hyperlipidemic ApoE-/- Mice

Tin Kyaw et al.

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Mycophenolate mofetil but not atorvastatin attenuates atherosclerosis in lupus-prone LDLr-/- mice

Sander I. van Leuven et al.

ANNALS OF THE RHEUMATIC DISEASES (2012)

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Use of statins is associated with an increased risk of rheumatoid arthritis

H. J. I. de Jong et al.

ANNALS OF THE RHEUMATIC DISEASES (2012)

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Local delivery of IL-2 reduces atherosclerosis via expansion of regulatory T cells

Thore Dietrich et al.

ATHEROSCLEROSIS (2012)

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Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis

Yvonne Doering et al.

CIRCULATION (2012)

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IgM autoantibodies to distinct apoptosis-associated antigens correlate with protection from cardiovascular events and renal disease in patients with SLE

Caroline Groenwall et al.

CLINICAL IMMUNOLOGY (2012)

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Association between Serum Total Antioxidant Status and Coronary Microvascular Functions in Patients with SLE

Sema Yilmaz et al.

ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES (2012)

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Pioglitazone improves the cardiovascular profile in patients with uncomplicated systemic lupus erythematosus: a double-blind randomized clinical trial

J. G. Juarez-Rojas et al.

LUPUS (2012)

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Accelerated atherosclerosis in patients with SLE-mechanisms and management

Brian J. Skaggs et al.

NATURE REVIEWS RHEUMATOLOGY (2012)

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Type I Interferons Are Associated with Subclinical Markers of Cardiovascular Disease in a Cohort of Systemic Lupus Erythematosus Patients

Emily C. Somers et al.

PLOS ONE (2012)

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Lupus Atherosclerosis Prevention Study (LAPS)

M. A. Petri et al.

ANNALS OF THE RHEUMATIC DISEASES (2011)

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Interferon-α Priming Promotes Lipid Uptake and Macrophage-Derived Foam Cell Formation A Novel Link Between Interferon-α and Atherosclerosis in Lupus

Jia Li et al.

ARTHRITIS AND RHEUMATISM (2011)

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Cardiac Troponin T Measured by a Highly Sensitive Assay Predicts Coronary Heart Disease, Heart Failure, and Mortality in the Atherosclerosis Risk in Communities Study

Justin T. Saunders et al.

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Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

Eneida Villanueva et al.

JOURNAL OF IMMUNOLOGY (2011)

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Endothelium-dependent But Not Endothelium-independent Flow-mediated Dilation Is Significantly Reduced in Patients with Systemic Lupus Erythematosus without Vascular Events: A Metaanalysis and Metaregression

Anselm Mak et al.

JOURNAL OF RHEUMATOLOGY (2011)

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MECHANISMS OF DISEASE Systemic Lupus Erythematosus

George C. Tsokos

NEW ENGLAND JOURNAL OF MEDICINE (2011)

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Numerical and functional deficiencies of natural killer T cells in systemic lupus erythematosus: their deficiency related to disease activity

Young-Nan Cho et al.

RHEUMATOLOGY (2011)

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Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

Roberto Lande et al.

SCIENCE TRANSLATIONAL MEDICINE (2011)

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Association Between Statin Use and Lupus-Like Syndrome Using Spontaneous Reports

Hilda J. I. de Jong et al.

SEMINARS IN ARTHRITIS AND RHEUMATISM (2011)

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Macrophage Activation and Coronary Atherosclerosis in Systemic Lupus Erythematosus and Rheumatoid Arthritis

Young Hee Rho et al.

ARTHRITIS CARE & RESEARCH (2011)

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Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease

Christian Lood et al.

BLOOD (2010)

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Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions

Pieter Goossens et al.

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Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death

Anurag Kumar Gupta et al.

FEBS LETTERS (2010)

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Nuclear Magnetic Resonance Lipoprotein Subclasses and the APOE Genotype Influence Carotid Atherosclerosis in Patients with Systemic Lupus Erythematosus

Marta Gonzalez et al.

JOURNAL OF RHEUMATOLOGY (2010)

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Peter Duewell et al.

NATURE (2010)

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Long-term improvement of lipid profile in patients with refractory systemic lupus erythematosus treated with B-cell depletion therapy: a retrospective observational study

Jose M. Pego-Reigosa et al.

RHEUMATOLOGY (2010)

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Platelet CD154 Potentiates Interferon-α Secretion by Plasmacytoid Dendritic Cells in Systemic Lupus Erythematosus

Pierre Duffau et al.

SCIENCE TRANSLATIONAL MEDICINE (2010)

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oxLDL/β2GPI complex and anti-oxLDL/β2GPI in SLE: Prevalence and correlates

N. Bassi et al.

AUTOIMMUNITY (2009)

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Cardiorespiratory Fitness as a Quantitative Predictor of All-Cause Mortality and Cardiovascular Events in Healthy Men and Women A Meta-analysis

Satoru Kodama et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)

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The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Improves Cardiometabolic Risk and Renal Inflammation in Murine Lupus

Wenpu Zhao et al.

JOURNAL OF IMMUNOLOGY (2009)

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Progression of carotid intima-media thickness and plaque in women with systemic lupus erythematosus

Trina Thompson et al.

ARTHRITIS AND RHEUMATISM (2008)

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General cardiovascular risk profile for use in primary care - The Framingham Heart Study

Ralph B. D'Agostino et al.

CIRCULATION (2008)

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Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus

Pui Y. Lee et al.

ARTHRITIS AND RHEUMATISM (2007)

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Inteirferon-α promotes abnormal vasculogenesis in lupus:: a potential pathway for premature atherosclerosis

Michael F. Denny et al.

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Identification of a novel role of T cells in postnatal vasculogenesis - Characterization of endothelial progenitor cell colonies

Jin Hur et al.

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Atorvastatin therapy improves endothelial-dependent vasodilation in patients with systemic lupus erythematosus: an 8 weeks controlled trial

G. A. Ferreira et al.

RHEUMATOLOGY (2007)

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Proinflammatory high-density lipoprotein as a biomarker for atherosclerosis in patients with systemic lupus erythematosus and rheumatoid arthritis

Maureen McMahon et al.

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Vascular diseases and their risk factors in IgA nephropathy

Juhani Myllymaki et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2006)

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Osteoprotegerin and osteopontin are expressed at high concentrations within symptomatic carotid atherosclerosis

J Golledge et al.

STROKE (2004)

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Assessment of atherosclerotic risk factors and endothelial function in children and young adults with pediatric-onset systemic lupus erythematosus

JB Soep et al.

ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH (2004)

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Endothelial cell apoptosis in systemic lupus erythematosus: a common pathway for abnormal vascular function and thrombosis propensity

S Rajagopalan et al.

BLOOD (2004)

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Circulating oxidized LDL forms complexes with β2-glycoprotein I:: implication as an atherogenic autoantigen

K Kobayashi et al.

JOURNAL OF LIPID RESEARCH (2003)

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Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

EC Baechler et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

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Antibodies to high-density lipoprotein and β2-glycoprotein I are inversely correlated with paraoxonase activity in systemic lupus erythematosus and primary antiphospholipid syndrome

JD Alves et al.

ARTHRITIS AND RHEUMATISM (2002)

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