Related references
Note: Only part of the references are listed.Whole-genome sequencing of East Asian lung cancers reveals new germline pathogenic variants
Semanti Mukherjee et al.
CANCER CELL (2022)
Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications
Jamal Majidpoor et al.
BIOMEDICINE & PHARMACOTHERAPY (2022)
Crosstalk between cancer-associated fibroblasts and immune cells in peritoneal metastasis: inhibition in the migration of M2 macrophages and mast cells by Tranilast
Yusuke Nakamura et al.
GASTRIC CANCER (2022)
Key promoters of tumor hallmarks
Keywan Mortezaee et al.
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2022)
Aging disrupts circadian gene regulation and function in macrophages
Eran Blacher et al.
NATURE IMMUNOLOGY (2022)
(Im)maturity in Tumor Ecosystem
Keywan Mortezaee et al.
FRONTIERS IN ONCOLOGY (2022)
βig-h3-structured collagen alters macrophage phenotype and function in pancreatic cancer
Sophie Bachy et al.
ISCIENCE (2022)
Pigment epithelium-derived factor, an anti-VEGF factor, delays ovarian cancer progression by alleviating polarization of tumor-associated macrophages
Rui Ma et al.
CANCER GENE THERAPY (2022)
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
Marah C. Runtsch et al.
CELL METABOLISM (2022)
PERK is a critical metabolic hub for immunosuppressive function in macrophages
Lydia N. Raines et al.
NATURE IMMUNOLOGY (2022)
M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway
Huaili Jiang et al.
CELL DEATH & DISEASE (2022)
Zeb1-induced metabolic reprogramming of glycolysis is essential for macrophage polarization in breast cancer
Huimin Jiang et al.
CELL DEATH & DISEASE (2022)
STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming
Zhaowei Chu et al.
NATURE COMMUNICATIONS (2022)
Roles for macrophage-polarizing interleukins in cancer immunity and immunotherapy
Keywan Mortezaee et al.
CELLULAR ONCOLOGY (2022)
Checkpoint inhibitor/interleukin-based combination therapy of cancer
Keywan Mortezaee et al.
CANCER MEDICINE (2022)
CD8+ T Cells in SARS-CoV-2 Induced Disease and Cancer-Clinical Perspectives
Keywan Mortezaee et al.
FRONTIERS IN IMMUNOLOGY (2022)
NK and cells with NK-like activities in cancer immunotherapy-clinical perspectives
Keywan Mortezaee et al.
MEDICAL ONCOLOGY (2022)
Exploration and functionalization of M1-macrophage extracellular vesicles for effective accumulation in glioblastoma and strong synergistic therapeutic effects
Xiaojun Wang et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)
Exosome-mediated genetic reprogramming of tumor-associated macrophages by exoASO-STAT6 leads to potent monotherapy antitumor activity
Sushrut Kamerkar et al.
SCIENCE ADVANCES (2022)
GARP: A Key Target to Evaluate Tumor Immunosuppressive Microenvironment
Alexanne Bouchard et al.
BIOLOGY-BASEL (2021)
Targeting MARCO and IL37R on Immunosuppressive Macrophages in Lung Cancer Blocks Regulatory T Cells and Supports Cytotoxic Lymphocyte Function
Linnea La Fleur et al.
CANCER RESEARCH (2021)
Redox tolerance and metabolic reprogramming in solid tumors
Keywan Mortezaee
CELL BIOLOGY INTERNATIONAL (2021)
Immune system in cancer radiotherapy: Resistance mechanisms and therapy perspectives
Keywan Mortezaee et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2021)
Enriched cancer stem cells, dense stroma, and cold immunity: Interrelated events in pancreatic cancer
Keywan Mortezaee
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2021)
Steps in metastasis: an updated review
Jamal Majidpoor et al.
MEDICAL ONCOLOGY (2021)
Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles
Zhaohan Wei et al.
NATURE COMMUNICATIONS (2021)
The impact of hypoxia on immune state in cancer
Keywan Mortezaee et al.
LIFE SCIENCES (2021)
Tumor-derived exosomal microRNA-106b-5p activates EMT-cancer cell and M2-subtype TAM interaction to facilitate CRC metastasis
Chaogang Yang et al.
MOLECULAR THERAPY (2021)
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages
Jennifer K. Dowling et al.
NATURE COMMUNICATIONS (2021)
High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming
Guangan Hu et al.
NATURE COMMUNICATIONS (2021)
Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
Natalia Ochocka et al.
NATURE COMMUNICATIONS (2021)
MyD88 in myofibroblasts enhances colitis-associated tumorigenesis via promoting macrophage M2 polarization
Qi Yuan et al.
CELL REPORTS (2021)
lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration
Yanyun Zhao et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2021)
Macrophages are metabolically heterogeneous within the tumor microenvironment
Xenia Geeraerts et al.
CELL REPORTS (2021)
The efficacy of PD-1/PD-L1 blockade in cold cancers and future perspectives
Jamal Majidpoor et al.
CLINICAL IMMUNOLOGY (2021)
Single-Cell RNA Sequencing Reveals the Heterogeneity of Tumor-Associated Macrophage in Non-Small Cell Lung Cancer and Differences Between Sexes
Qi Yang et al.
FRONTIERS IN IMMUNOLOGY (2021)
Organ tropism in solid tumor metastasis: an updated review
Keywan Mortezaee
FUTURE ONCOLOGY (2021)
Sodium/glucose cotransporter 1-dependent metabolic alterations induce tamoxifen resistance in breast cancer by promoting macrophage M2 polarization
Xingjian Niu et al.
CELL DEATH & DISEASE (2021)
Angiogenesis as a hallmark of solid tumors-clinical perspectives
Jamal Majidpoor et al.
CELLULAR ONCOLOGY (2021)
Normalization in tumor ecosystem: Opportunities and challenges
Keywan Mortezaee
CELL BIOLOGY INTERNATIONAL (2021)
Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming
Samantha M. Morrissey et al.
CELL METABOLISM (2021)
Interleukin-2 therapy of cancer-clinical perspectives
Jamal Majidpoor et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2021)
The current knowledge concerning solid cancer and therapy
Masoud Najafi et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2021)
Myeloid-derived suppressor cells in cancer immunotherapy-clinical perspectives
Keywan Mortezaee
LIFE SCIENCES (2021)
Metabolic Anti-Cancer Effects of Melatonin: Clinically Relevant Prospects
Marek Samec et al.
CANCERS (2021)
Pancreatic cancer cells render tumor-associated macrophages metabolically reprogrammed by a GARP and DNA methylation-mediated mechanism
Mengwen Zhang et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)
Targeting tumor-associated macrophages to synergize tumor immunotherapy
Xiaonan Xiang et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)
The IL-33/ST2 axis affects tumor growth by regulating mitophagy in macrophages and reprogramming their polarization
Huadan Xu et al.
CANCER BIOLOGY & MEDICINE (2021)
Immune metabolism in PD-1 blockade-based cancer immunotherapy
Alok Kumar et al.
INTERNATIONAL IMMUNOLOGY (2021)
Resveratrol as an Adjuvant for Normal Tissues Protection and Tumor Sensitization
Keywan Mortezaee et al.
CURRENT CANCER DRUG TARGETS (2020)
Hypoxia induces core-to-edge transition of progressive tumoral cells: A critical review on differential yet corroborative roles for HIF-1α and HIF-2α
Keywan Mortezaee
LIFE SCIENCES (2020)
Combining microenvironment normalization strategies to improve cancer immunotherapy
Fotios Mpekris et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway
Caihong Wang et al.
CELL REPORTS (2020)
Lactic Acidosis Together with GM-CSF and M-CSF Induces Human Macrophages toward an Inflammatory Protumor Phenotype
Lea Paolini et al.
CANCER IMMUNOLOGY RESEARCH (2020)
Reprogramming of tumor-associated macrophages by targeting beta-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer
Poonam Sarode et al.
SCIENCE ADVANCES (2020)
CCL8 Promotes Postpartum Breast Cancer by Recruiting M2 Macrophages
Elena Farmaki et al.
ISCIENCE (2020)
ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages
Jinlong Yin et al.
NATURE COMMUNICATIONS (2020)
Multi-omics analysis identifies FoxO1 as a regulator of macrophage function through metabolic reprogramming
Kai Yan et al.
CELL DEATH & DISEASE (2020)
Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis
Lang Rao et al.
NATURE COMMUNICATIONS (2020)
Pyruvate Kinase M2 Coordinates Metabolism Switch between Glycolysis and Glutaminolysis in Cancer Cells
Liangwei Li et al.
ISCIENCE (2020)
Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer
Taekyoung Kwak et al.
CELL REPORTS (2020)
Disruption of the redox balance with either oxidative or anti-oxidative overloading as a promising target for cancer therapy
Bagher Farhood et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets
Luca Cassetta et al.
CANCER CELL (2019)
Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade
Ying Zhu et al.
GUT (2019)
Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response
Camilla Salvagno et al.
NATURE CELL BIOLOGY (2019)
Regulatory T cells in cancer immunosuppression - implications for anticancer therapy
Yosuke Togashi et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2019)
Cryo-thermal therapy induces macrophage polarization for durable anti-tumor immunity
Kun He et al.
CELL DEATH & DISEASE (2019)
Deciphering Macrophage and Monocyte Code to Stratify Human Breast Cancer Patients
Vincenzo Bronte
CANCER CELL (2019)
IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization
Moritz F. Eissmann et al.
NATURE COMMUNICATIONS (2019)
Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer
Asmaa El-Kenawi et al.
BRITISH JOURNAL OF CANCER (2019)
Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
Joseph L. Benci et al.
CELL (2019)
Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer
Pawel Bieniasz-Krzywiec et al.
CELL METABOLISM (2019)
Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial
E. Antonio Chiocca et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer
Diletta Di Mitri et al.
CELL REPORTS (2019)
Cancer-derived exosomes loaded with ultrathin palladium nanosheets for targeted bioorthogonal catalysis
Maria Sancho-Albero et al.
NATURE CATALYSIS (2019)
Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies
Yun-Chieh Sung et al.
NATURE NANOTECHNOLOGY (2019)
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
Kathrin Renner et al.
CELL REPORTS (2019)
Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches
Karen G. de la Cruz-Lopez et al.
FRONTIERS IN ONCOLOGY (2019)
Stromal reprogramming: A target for tumor therapy
Masoud Najafi et al.
LIFE SCIENCES (2019)
Metabolic Alterations in Aging Macrophages: Ingredients for Inflammaging?
Adriaan A. van Beek et al.
TRENDS IN IMMUNOLOGY (2019)
NADPH Oxidase as a Target for Modulation of Radiation Response; Implications to Carcinogenesis and Radiotherapy
Keywan Mortezaee et al.
CURRENT MOLECULAR PHARMACOLOGY (2019)
Metformin as a Radiation Modifier; Implications to Normal Tissue Protection and Tumor Sensitization
Keywan Mortezaee et al.
CURRENT CLINICAL PHARMACOLOGY (2019)
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) and liver fibrosis: A review
Keywan Mortezaee
CELL BIOCHEMISTRY AND FUNCTION (2018)
Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype (vol 9, 873, 2018)
Degao Chen et al.
NATURE COMMUNICATIONS (2018)
Macrophages orchestrate breast cancer early dissemination and metastasis
Nina Linde et al.
NATURE COMMUNICATIONS (2018)
Tumor-Associated CD204-Positive Macrophage Is a Prognostic Marker in Clinical Stage I Lung Adenocarcinoma
Yanbin Sun et al.
BIOMED RESEARCH INTERNATIONAL (2018)
Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity
Feilong Wang et al.
EBIOMEDICINE (2018)
Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation
Feilong Wang et al.
CELL METABOLISM (2018)
Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
Toszka Bohn et al.
NATURE IMMUNOLOGY (2018)
Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer
Marta Helena Kubala et al.
CELL REPORTS (2018)
Cancer-associated fibroblasts promote an immunosuppressive microenvironment through the induction and accumulation of protumoral macrophages
Hideyuki Takahashi et al.
ONCOTARGET (2017)
Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis
Erika M. Palmieri et al.
CELL REPORTS (2017)
Expression of GARP Is Increased in Tumor-Infiltrating Regulatory T Cells and Is Correlated to Clinicopathology of Lung Cancer Patient
Hao Jin et al.
FRONTIERS IN IMMUNOLOGY (2017)
Aerobic glycolysis and high level of lactate in cancer metabolism and microenvironment
Bo Jiang
GENES & DISEASES (2017)
Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
Vinit Kumar et al.
CANCER CELL (2017)
Preconditioning with melatonin improves therapeutic outcomes of bone marrow-derived mesenchymal stem cells in targeting liver fibrosis induced by CCl4
Keywan Mortezaee et al.
CELL AND TISSUE RESEARCH (2017)
Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer
Alexander Hamm et al.
GUT (2016)
Influence of Circulating Tumour Cells on Production of IL-1α, IL-1β and IL-12 in Sera of Patients with Primary Diagnosis of Breast Cancer Before Treatment
Theresa Vilsmaier et al.
ANTICANCER RESEARCH (2016)
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
Evanna L. Mills et al.
CELL (2016)
Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis
Mathias Wenes et al.
CELL METABOLISM (2016)
Tumor Associated Macrophages in Kidney Cancer
Olga V. Kovaleva et al.
ANALYTICAL CELLULAR PATHOLOGY (2016)
Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis
Anna-Maria Georgoudaki et al.
CELL REPORTS (2016)
Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
Eva M. Palsson-McDermott et al.
CELL METABOLISM (2015)
TNF Counterbalances the Emergence of M2 Tumor Macrophages
Franz Kratochvill et al.
CELL REPORTS (2015)
Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
Abhishek K. Jha et al.
IMMUNITY (2015)
A Positive Feedback Loop between Mesenchymal-like Cancer Cells and Macrophages Is Essential to Breast Cancer Metastasis
Shicheng Su et al.
CANCER CELL (2014)
Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy
Carola H. Ries et al.
CANCER CELL (2014)
Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population
Damya Laoui et al.
CANCER RESEARCH (2014)
CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models
Yu Zhu et al.
CANCER RESEARCH (2014)
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
Oscar R. Colegio et al.
NATURE (2014)
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
Stanley Ching-Cheng Huang et al.
NATURE IMMUNOLOGY (2014)
Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression
G. Comito et al.
ONCOGENE (2014)
mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity
Shih-Chin Cheng et al.
SCIENCE (2014)
Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy
Felix Klug et al.
CANCER CELL (2013)
Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity
Andrea Casazza et al.
CANCER CELL (2013)
Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages
Geethanjali Pickert et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
G. M. Tannahill et al.
NATURE (2013)
Therapeutically reeducating macrophages to treat GBM
Christopher Garris et al.
NATURE MEDICINE (2013)
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Stephanie M. Pyonteck et al.
NATURE MEDICINE (2013)
Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress
Gregory LaMonte et al.
CANCER & METABOLISM (2013)
Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity
Rodrigo Leite de Oliveira et al.
CANCER CELL (2012)
HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PIGF
Charlotte Rolny et al.
CANCER CELL (2011)
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
Weibo Luo et al.
CELL (2011)
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
Dimitrios Anastasiou et al.
SCIENCE (2011)
Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization
Massimiliano Mazzone et al.
CELL (2009)