From Classic to Modern Prognostic Biomarkers in Patients with Acute Myocardial Infarction

Article Medicine, General & Internal

Uric acid associated with acute heart failure presentation in Acute Coronary Syndrome patients

Paola Rebora et al.

Summary: The study demonstrated a significant association between uric acid levels and acute heart failure, cardiogenic shock, non-invasive ventilation use, and left ventricular ejection fraction in patients with acute coronary syndromes.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2022)

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Review Biochemistry & Molecular Biology

The Role of Matrix Proteins in Cardiac Pathology

Katie Trinh et al.

Summary: The extracellular matrix and ECM-regulatory proteins play crucial roles in cardiac development, organ remodeling, and injury repair. They possess diverse functionality regulated by multiple structural domains and interactions with extracellular substrates and/or cell surface receptors. Various cell types within the myocardium produce ECM proteins, and their importance in cardiovascular physiology and pathology has been increasingly recognized. Understanding the contribution of ECM to cardiovascular disease provides potential pharmacological targets for cardiac diseases and beyond.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Article Cardiac & Cardiovascular Systems

Novel multi-marker proteomics in phenotypically matched patients with ST-segment myocardial infarction: association with clinical outcomes

Jay S. Shavadia et al.

Summary: The study suggests significant heterogeneity in early proteomic responses among acutely reperfused STEMI patients who develop death, heart failure, or shock within 90 days. It recommends considering synergistic multi-biomarker strategies for risk stratification and guiding future development of novel post-myocardial infarction therapies.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2022)

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Article Cardiac & Cardiovascular Systems

Relationship between plasma Neuregulin-1 and cardiac function in patients with ST-elevation myocardial infarction

Paul M. Haller et al.

Summary: The level of NRG-1 is affected in patients with acute myocardial infarction (MI). Further large clinical trials are needed to confirm this hypothesis.

REVIEWS IN CARDIOVASCULAR MEDICINE (2022)

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Article Cardiac & Cardiovascular Systems

Elevated Cystatin-C Levels Are Associated with Increased Mortality in Acute Coronary Syndrome Patients: An HIJ-PROPER Sub-Analysis

Takashi Saito et al.

Summary: This study investigated the association between serum cystatin-C (Cys-C) levels and cardiovascular events in patients with acute coronary syndrome (ACS). The results showed that elevated Cys-C levels were associated with increased all-cause mortality but not with other cardiovascular events in ACS patients.

CARDIORENAL MEDICINE (2022)

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Article Medicine, General & Internal

Procalcitonin Predicts Bacterial Infection, but Not Long-Term Occurrence of Adverse Events in Patients with Acute Coronary Syndrome

Rita Pavasini et al.

Summary: This study investigates the predictive value of procalcitonin (PCT) levels for bacterial infection and long-term outcomes in patients with acute coronary syndromes (ACS). Results suggest that PCT levels can predict bacterial infections but not all-cause mortality, stroke, or myocardial infarction in ACS patients.

JOURNAL OF CLINICAL MEDICINE (2022)

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Article Health Care Sciences & Services

Analysis of correlation between heart failure in the early stage of acute myocardial infarction and serum pregnancy associated plasma protein-A, prealbumin, C-reactive protein, and brain natriuretic peptide levels

Yang Yang et al.

Summary: The study showed that PAPP-A, PAB, CRP, and BNP are independent influencing factors of HF after AMI, and comprehensive tests of these indicators are more accurate in predicting and evaluating HF.

ANNALS OF PALLIATIVE MEDICINE (2022)

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Review Cardiac & Cardiovascular Systems

Endocan: A Key Player of Cardiovascular Disease

Jinzhi Chen et al.

Summary: Endocan, also known as endothelial cell specific molecule-1, is a soluble proteoglycan mainly secreted by endothelial cells. Increased plasma levels of endocan may reflect endothelial activation and dysfunction, and are considered a potential immuno-inflammatory marker related to cardiovascular disease. Endocan shows promise as a prognostic biomarker for cardiovascular disease, but further research into its mechanisms of action is needed.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

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Review Cardiac & Cardiovascular Systems

Serum cystatin C is associated with the prognosis in acute myocardial infarction patients after coronary revascularization: a systematic review and meta-analysis

Jun Chen et al.

Summary: There is an association between serum cystatin C levels and higher risk of major cardiovascular events (MACEs) and mortality in AMI patients after PCI.

BMC CARDIOVASCULAR DISORDERS (2022)

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Review Biotechnology & Applied Microbiology

High-Sensitivity Troponin: A Review on Characteristics, Assessment, and Clinical Implications

Diana Raluca Lazar et al.

Summary: High-sensitivity cardiac troponin assays play a crucial role in diagnosing myocardial infarctions and have the potential to reduce diagnostic time. They are also valuable prognostic markers for long-term events and mortality in various cardiovascular and non-cardiovascular conditions. However, challenges still exist in interpreting the results, especially in patients with basal elevation and regarding various analytical characteristics.

DISEASE MARKERS (2022)

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Article Biotechnology & Applied Microbiology

Association between Cystatin C and Cardiac Function in Acute Myocardial Infarction Patients: A Real-World Analysis

Bowen Lou et al.

Summary: The study explores the relationship between in-hospital Cystatin C (CysC) and cardiac function and subsequent prognosis among patients with acute myocardial infarction (AMI). The findings suggest that admission CysC is negatively correlated with cardiac function in AMI patients and acts as a novel predictor for major adverse cardiovascular events (MACE) in the whole population.

DISEASE MARKERS (2022)

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Article Cell Biology

A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk

Stephen A. Williams et al.

Summary: Using a combination of proteins can be a reliable predictor of cardiovascular risk, improving drug development and patient outcomes.

SCIENCE TRANSLATIONAL MEDICINE (2022)

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Article Endocrinology & Metabolism

Hyperuricemia is Associated With 2-and 5-Year Adverse Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention

Xiao-Fang Tang et al.

Summary: The study found that hyperuricemia is associated with higher risks of 2- and 5-year all-cause deaths in patients with STEMI undergoing PCI. However, no correlation was found between hyperuricemia and inflammatory responses in newly admitted STEMI patients.

FRONTIERS IN ENDOCRINOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Neuropeptide-Y Levels in ST-Segment-Elevation Myocardial Infarction: Relationship With Coronary Microvascular Function, Heart Failure, and Mortality

Thomas Gibbs et al.

Summary: The study found that peripheral venous NPY levels in patients with ST-segment-elevation myocardial infarction are associated with microvascular function and infarct size. High NPY levels are also associated with an increased incidence of heart failure and mortality.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2022)

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Article Cardiac & Cardiovascular Systems

Serum microRNAs are key predictors of long-term heart failure and cardiovascular death after myocardial infarction

Luis M. Rincon et al.

Summary: This study evaluated the prognostic value of circulating miRNAs for heart failure-related events among MI patients. It found that several miRNAs reliably predicted HF hospitalizations, cardiovascular mortality, and poor long-term NYHA status, improving current risk prediction methods.

ESC HEART FAILURE (2022)

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Article Medicine, General & Internal

Trend of Galectin-3 Levels in Patients with Non-ST-Elevation and ST-Elevation Myocardial Infarction

Branka Mitic et al.

Summary: In the early post-MI period, plasma galectin-3 levels mainly correlate with atherosclerosis factors, while on day 30, it correlates with diastolic dysfunction and left ventricular remodeling.

MEDICINA-LITHUANIA (2022)

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Article Medicine, General & Internal

Mid -regional pro -adrenomedullin and lactate dehydrogenase as predictors of left ventricular remodeling in patients with myocardial infarction treated with percutaneous coronary intervention

Michal Wegiel et al.

Summary: This study assessed the relationship between circulating biomarkers and left ventricular function after myocardial infarction (MI). The results indicate that LDH and MR-pro ADM may be promising biomarkers of adverse remodeling, and higher levels of these biomarkers are associated with a reduced chance of favorable reverse remodeling occurrence in MI patients.

POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ (2022)

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Article Peripheral Vascular Disease

Serum Endocan Levels Predict Angiographic No-Reflow Phenomenon in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Coronary Intervention

Mustafa Dogdus et al.

Summary: The study revealed a relationship between Endocan levels and NRP in STEMI patients, with Endocan >2.7 ng/mL serving as a sensitive and specific predictor for NRP. Endocan levels may assist in identifying patients at higher risk of inadequate myocardial perfusion and worse clinical outcomes.

ANGIOLOGY (2021)

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Article Cardiac & Cardiovascular Systems

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

Jean-Philippe Collet et al.

EUROPEAN HEART JOURNAL (2021)

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Review Cardiac & Cardiovascular Systems

Diagnostic Value of sST2 in Cardiovascular Diseases: A Systematic Review and Meta-Analysis

Tianyi Zhang et al.

Summary: This study investigated soluble ST2 levels in patients with ischemic heart disease, myocardial infarction, and heart failure, and found that soluble ST2 levels are significantly associated with heart failure but not with ischemic heart disease or myocardial infarction.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)

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Article Emergency Medicine

The additive value of copeptin for early diagnosis and prognosis of acute coronary syndromes

Tarek A. N. Ahmed et al.

Summary: This study assessed the value of copeptin for the early diagnosis and prognosis of non-ST segment acute coronary syndromes, finding that high copeptin levels on admission were associated with a higher risk of major adverse cardiac events (MACEs). The combination of copeptin and conventional troponin I showed a higher sensitivity and negative predictive value for ruling out NSTEMI, with excellent prognostic value for risk stratification and prediction of MACEs.

AMERICAN JOURNAL OF EMERGENCY MEDICINE (2021)

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Article Cardiac & Cardiovascular Systems

Association of atrial arrhythmias with thrombospondin-1 in patients with acute myocardial infarction

Wenkai Liao et al.

Summary: The study found that elevated TSP-1 levels were an independent risk factor for atrial arrhythmias in AMI patients, along with old age, high Hs-CRP levels, and poor heart function.

BMC CARDIOVASCULAR DISORDERS (2021)

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Article Medicine, General & Internal

Higher serum level of Cystatin C An additional risk factor of CAD

Zhenfei Chen et al.

Summary: The study revealed a positive correlation between serum Cystatin C levels and the severity of coronary artery lesions, Gensini score (GS), and the risk of coronary artery disease (CAD). Cystatin C can be a promising clinical biomarker for evaluating CAD risk and severity of coronary artery lesions.

MEDICINE (2021)

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Article Multidisciplinary Sciences

Mid-regional pro-adrenomedullin is a novel biomarker for arterial stiffness as the criterion for vascular failure in a cross-sectional study

Teruhide Koyama et al.

Summary: This study suggests that MR-proADM may be a more suitable biomarker for arterial stiffness as the criterion for vascular failure compared to hsCRP. MR-proADM showed higher accuracy in the index of vascular failure and was significantly associated with baPWV.

SCIENTIFIC REPORTS (2021)

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Article Medicine, General & Internal

Copeptin is associated with mortality in elderly people

Maria Isabel Smaradottir et al.

Summary: Elevated copeptin, a marker for vasopressin release, is associated with impaired prognosis in acute myocardial infarction. This study found that copeptin levels were higher in individuals with previous MI, regardless of whether it was recognized or not. Copeptin showed weak correlation with cortisol and NTproBNP, and remained independently associated with total mortality in a multiple model analysis.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2021)

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Editorial Material Cardiac & Cardiovascular Systems

Cardiac myosin-binding protein C as a candidate biomarker in heart failure: rational but not revolutionary

A. Mark Richards

EUROPEAN JOURNAL OF HEART FAILURE (2021)

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Article Medicine, Research & Experimental

Clinical diagnostic value of combined detection of IMA, D-D and MCP-1 in acute myocardial infarction

Mei Ding et al.

Summary: The levels of IMA, D-D, and MCP-1 in AMI patients are significantly higher than those in the control group, and they are positively correlated with CTnT and hs-CRP levels. Combined detection of IMA, D-D, and MCP-1 can improve the accuracy of AMI diagnosis.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2021)

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Article Biochemistry & Molecular Biology

C-Reactive Protein as a Risk Marker for Post-Infarct Heart Failure over a Multi-Year Period

Iwona Swiatkiewicz et al.

Summary: Elevated high-sensitivity C-reactive protein concentration is associated with heart failure development post-STEMI, indicating a potential role in long-term risk prediction for heart failure.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Review Medicine, General & Internal

The Role of Uric Acid in Acute and Chronic Coronary Syndromes

Alessandro Maloberti et al.

Summary: Uric acid is not only associated with articular gout and kidney disease, but also with cardiovascular diseases. It has been linked to various outcomes such as mortality, cardiovascular events, heart failure, atrial fibrillation, and strokes. The potential impact of pharmacologically reducing uric acid on lowering the incidence of cardiovascular events remains a topic of discussion.

JOURNAL OF CLINICAL MEDICINE (2021)

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Article Medicine, General & Internal

Mean platelet volume/platelet count ratio as a predictor of stent thrombosis in patients with ST-segment-elevation myocardial infarction

Altug Osken et al.

Summary: This study aimed to investigate the association between the mean platelet volume (MPV) to platelet count (PC) ratio and long-term stent thrombosis (ST) and mortality in patients with ST-segment-elevation myocardial infarction (STEMI) treated successfully by primary percutaneous coronary intervention (pPCI). The results showed that higher MPV/PC ratios were associated with long-term ST and mortality, suggesting that this ratio may be a valuable parameter for identifying high-risk patients who have undergone pPCI.

IRISH JOURNAL OF MEDICAL SCIENCE (2021)

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Editorial Material Cardiac & Cardiovascular Systems

Cardiac myosin-binding protein C as a biomarker of acute myocardial infarction

Michael S. Marber et al.

EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE (2021)

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Article Medicine, Research & Experimental

Predicting long-term cardiovascular outcomes in myocardial infarction survivors using multiple biomarkers

Mustafa U. Somuncu et al.

Summary: This study analyzed biomarkers of 259 myocardial infarction patients and found that high myocardial stress and inflammation markers were associated with major cardiovascular adverse events, while myonecrosis markers were not clearly related.

BIOMARKERS IN MEDICINE (2021)

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Article Cardiac & Cardiovascular Systems

Predictive value of creatine kinase MB for contrast-induced acute kidney injury among myocardial infarction patients

Wen Wei et al.

Summary: This study evaluated the predictive value of CK-MB for CI-AKI among MI patients, finding that CK-MB was independently associated with CI-AKI. Additionally, integrating CK-MB with ACEF score, Mehran score A, and Mehran score B resulted in increased C-statistics. Internal validation showed consistent results, and external validation demonstrated good discrimination and calibration.

BMC CARDIOVASCULAR DISORDERS (2021)

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Article Cardiac & Cardiovascular Systems

Predictive value of CHADS2 and CHA2DS2-VASc scores for coronary artery lesions and in-hospital prognosis of patients with acute ST-segment elevation myocardial infarction

Xiaoli Li et al.

Summary: The CHADS(2) score is useful in predicting the severity of coronary lesions and the presence of left main coronary artery in STEMI patients, while the CHA(2)DS(2)-VASc score lacks predictive ability in these aspects. Both scores are predictive of patient hospitalization time and adverse events during hospitalization, but not for the number of coronary lesions and the location of target lesions in STEMI patients.

BMC CARDIOVASCULAR DISORDERS (2021)

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Article Medicine, Research & Experimental

Circulating LIPCAR is a potential biomarker of heart failure in patients post-acute myocardial infarction

Li Yan et al.

Summary: The study found that LIPCAR levels were elevated in HF patients post-AMI and had a high predictive value for the diagnosis of HF, suggesting that LIPCAR may serve as a marker for early HF after AMI.

EXPERIMENTAL BIOLOGY AND MEDICINE (2021)

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Article Cardiac & Cardiovascular Systems

Implications of Periprocedural Myocardial Biomarker Elevations and Commonly Used MI Definitions After Left Main PCI

Hao-Yu Wang et al.

Summary: This study found that in patients undergoing LM PCI, high levels of peak postprocedural CK-MB were independently associated with 3-year CV mortality, while elevated post-PCI cTnI did not predict mortality. The SCAI definition of PMI was significantly associated with mortality after LM PCI, while ARC-2 and UDMI definitions were not.

JACC-CARDIOVASCULAR INTERVENTIONS (2021)

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Article Medicine, Research & Experimental

Factors associated with microvascular occlusion in patients with ST elevation myocardial infarction after primary percutaneous coronary intervention

Yinhao Huang et al.

Summary: This study aimed to determine predictors of microvascular occlusion in patients with STEMI after pPCI, finding that CRP, TnT, and syndecan-1 levels can be used as serum biomarkers for MVO in these patients. These factors were independently associated with the occurrence of MVO.

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2021)

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Article Respiratory System

Prognostic value of copeptin in patients with acute myocardial infarction treated with percutaneous coronary intervention: a prospective cohort study

Marta Roczek-Janowska et al.

Summary: The study found that elevated copeptin concentration on the 4th/5th day of hospitalisation was associated with major adverse cardiovascular events in patients with first acute myocardial infarction. Additionally, copeptin concentration and left ventricular ejection fraction were identified as the only predictors for major adverse cardiac events during follow-up. These findings suggest that copeptin may serve as a prognostic marker in this patient population.

JOURNAL OF THORACIC DISEASE (2021)

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Article Cardiac & Cardiovascular Systems

Prognostic role of procalcitonin in ST-elevation myocardial infarction complicated by cardiogenic shock

Yash Paul Sharma et al.

Summary: This study aimed to evaluate the prognostic value of procalcitonin in ST-elevation myocardial infarction complicated by cardiogenic shock. While elevated procalcitonin was related to in-hospital mortality, it was not an independent predictor. Additional prospective studies are needed to assess the role of serial procalcitonin monitoring in these cases.

ASIAN CARDIOVASCULAR & THORACIC ANNALS (2021)

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Article Medicine, General & Internal

Prognostic value of the C-reactive protein to albumin ratio in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction

Ozgur Sogut et al.

Summary: The study indicated that the baseline CRP/albumin ratio is associated with infarct localization, number of vascular lesions, and in-hospital mortality in patients with STEMI undergoing primary PCI. Furthermore, the CRP/albumin ratio and number of coronary artery lesions were identified as independent predictors of mortality, with >_ 2 vessel lesions being the most important predictor of mortality in STEMI patients.

TURKISH JOURNAL OF MEDICAL SCIENCES (2021)

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Article Medicine, General & Internal

Predicting mortality with cardiac troponins: recent insights from meta-analyses

Giuseppe Lippi et al.

Summary: The introduction of cardiac troponin testing has been a crucial advancement in clinical practice, essential for diagnosing acute coronary syndrome. Studies have shown that cTn values can predict mortality risk in both healthy individuals and patients with a variety of cardiac and non-cardiac diseases.

DIAGNOSIS (2021)

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Article Medicine, General & Internal

Evaluation of Heart-type Fatty Acid-binding Protein in Early Diagnosis of Acute Myocardial Infarction

Mi-Gil Moon et al.

Summary: H-FABP is an effective early diagnostic marker for AMI with higher accuracy than other cardiac markers, especially within 4 hours of symptom onset. It is correlated with post-AMI LV dysfunction but not the extent of CAD.

JOURNAL OF KOREAN MEDICAL SCIENCE (2021)

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Article Medicine, Research & Experimental

The AMPK-mTOR axis requires increased MALAT1 expression for promoting granulosa cell proliferation in endometriosis

Xuejie Liu et al.

Summary: The study revealed that MALAT1 in granulosa cells of endometriosis plays a role in promoting cell proliferation, inhibiting apoptosis, and enhancing autophagy, possibly through regulating the AMPK-mTOR signaling pathway.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2021)

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Article Health Care Sciences & Services

Association between N-terminal pro-BNP and 12 months major adverse cardiac events among patients admitted with NSTEMI

Xiaowen Gong et al.

Summary: NT-proBNP is a robust long-term prognostic biomarker for NSTEMI patients, especially for older patients and those with impaired cardiac ejection function. Combined usage of NT-proBNP levels with the GRACE score might help identify a subset of NSTEMI patients at a particularly high risk of MACEs 12 months after discharge.

ANNALS OF PALLIATIVE MEDICINE (2021)

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Article Cardiac & Cardiovascular Systems

Evolution of renal function and predictive value of serial renal assessments among patients with acute coronary syndrome: BIOMArCS study

Milos Brankovic et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Predictive risk factors of early onset left ventricular aneurysm formation in patients with acute ST-elevation myocardial infarction

Zenghui Zhang et al.

HEART & LUNG (2020)

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Article Cardiac & Cardiovascular Systems

Predictive value of fibrinogen-to-albumin ratio in acute coronary syndrome

M. Cetin et al.

HERZ (2020)

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Article Cardiac & Cardiovascular Systems

Prognostic value of serum uric acid levels in patients with non-STEMI undergoing percutaneous coronary intervention

Yigit Canga et al.

HERZ (2020)

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Article Medicine, General & Internal

Predictive value of soluble suppression of tumourigenicity 2 on myocardial reperfusion

Shiru Bai et al.

INTERNAL MEDICINE JOURNAL (2020)

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Review Cardiac & Cardiovascular Systems

Value of Galectin-3 in Acute Myocardial Infarction

Mingxing Li et al.

AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS (2020)

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Article Oncology

Interleukin-37 is increased in peripheral blood mononuclear cells of coronary heart disease patients and inhibits the inflammatory reaction

Huimin Li et al.

MOLECULAR MEDICINE REPORTS (2020)

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Review Peripheral Vascular Disease

Inflammatory and Hematological Indices as Simple, Practical Severity Predictors of Microdysfunction Following Coronary Intervention: A Systematic Review and Meta-Analysis

Enyuan Zhang et al.

ANGIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Plasma BNP Levels and Diuretics Use as Predictors of Cardiovascular Events in Patients with Myocardial Infarction and Impaired Glucose Tolerance

Kazuhiro Shindo et al.

CARDIOVASCULAR DRUGS AND THERAPY (2020)

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Article Cardiac & Cardiovascular Systems

Comparison of prognostic significance between serum fibrinogen and Global Registry of Acute Coronary Events score for prognosis of patients with non-ST-elevation acute coronary syndromes undergoing percutaneous coronary intervention

Jia Song et al.

CORONARY ARTERY DISEASE (2020)

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Article Cardiac & Cardiovascular Systems

The cardiac sympathetic co-transmitter neuropeptide Y is pro-arrhythmic following ST-elevation myocardial infarction despite beta-blockade

Manish Kalla et al.

EUROPEAN HEART JOURNAL (2020)

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Article Medicine, General & Internal

Combining Novel Biomarkers for Risk Stratification of Two-Year Cardiovascular Mortality in Patients with ST-Elevation Myocardial Infarction

Naufal Zagidullin et al.

JOURNAL OF CLINICAL MEDICINE (2020)

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Article Cardiac & Cardiovascular Systems

Comparison of interleukin-6, C-reactive protein, and low-density lipoprotein cholesterol as biomarkers of residual risk in contemporary practice: secondary analyses from the Cardiovascular Inflammation Reduction Trial

Paul M. Ridker et al.

EUROPEAN HEART JOURNAL (2020)

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Article Medicine, Research & Experimental

The relation of endocan and galectin-3 with ST-segment resolution in patients with ST-segment elevation myocardial infarction

Yasar Turan et al.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE (2020)

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Article Medicine, General & Internal

Galectin-3 as the Prognostic Factor of Adverse Cardiovascular Events in Long-Term Follow up in Patients after Myocardial Infarction-A Pilot Study

Przemyslaw Swiecki et al.

JOURNAL OF CLINICAL MEDICINE (2020)

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Review Medicine, General & Internal

Heart-type fatty acid-binding protein: an overlooked cardiac biomarker

Harsh Goel et al.

ANNALS OF MEDICINE (2020)

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Review Medical Laboratory Technology

Soluble ST2: A complex and diverse role in several diseases

Evgenija Homsak et al.

CLINICA CHIMICA ACTA (2020)

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Review Biotechnology & Applied Microbiology

Adverse Cardiac Remodelling after Acute Myocardial Infarction: Old and New Biomarkers

Alexander E. Berezin et al.

DISEASE MARKERS (2020)

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Article Medicine, General & Internal

Impact of admission serum acid uric levels on in-hospital outcomes in patients with acute coronary syndrome

Marco Centola et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2020)

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Article Cardiac & Cardiovascular Systems

Growth differentiation factor-15 is associated with cardiovascular outcomes in patients with coronary artery disease

Man Li et al.

CARDIOVASCULAR DIABETOLOGY (2020)

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Review Medicine, Research & Experimental

Neuregulin-1, a microvascular endothelial-derived protein, protects against myocardial ischemia-reperfusion injury (Review)

Yuhao Lin et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2020)

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Article Medicine, General & Internal

Association of Myocardial Injury With Serum Procalcitonin Levels in Patients With ST-Elevation Myocardial Infarction

Martin Reindl et al.

JAMA NETWORK OPEN (2020)

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Article Medicine, General & Internal

Leukocyte Rho kinase activity and serum cystatin C affect cardiovascular events in acute coronary syndrome

Li Ma et al.

MEDICINE (2020)

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Article Cardiac & Cardiovascular Systems

Establishment and validation of a risk model for prediction of in-hospital mortality in patients with acute ST-elevation myocardial infarction after primary PCI

Nan Gao et al.

BMC CARDIOVASCULAR DISORDERS (2020)

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Article Medicine, General & Internal

Copeptin levels predict left ventricular systolic function in STEMI patients A 2D speckle tracking echocardiography-based prospective observational study

Hilal Erken Pamukcu et al.

MEDICINE (2020)

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Review Biochemistry & Molecular Biology

Post-Myocardial Infarction Ventricular Remodeling Biomarkers-The Key Link between Pathophysiology and Clinic

Maria-Madalina Bostan et al.

BIOMOLECULES (2020)

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Article Oncology

Heart-type fatty acid binding protein predicts cardiovascular events in patients with stable coronary artery disease: a prospective cohort study

Hui-Wen Zhang et al.

ANNALS OF TRANSLATIONAL MEDICINE (2020)

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Article Cardiac & Cardiovascular Systems

Usefulness of High Sensitivity Troponin T to Predict Long-Term Left Ventricular Dysfunction After ST-Elevation Myocardial Infarction

Moman A. Mohammad et al.

AMERICAN JOURNAL OF CARDIOLOGY (2020)

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Article Medicine, General & Internal

Liver parameters as part of a non-invasive model for prediction of all-cause mortality after myocardial infarction

Theodor Baars et al.

ARCHIVES OF MEDICAL SCIENCE (2020)

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Review Cardiac & Cardiovascular Systems

Remote ischaemic conditioning for myocardial infarction or elective PCI: systematic review and meta-analyses of randomised trials

Paul M. Haller et al.

EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE (2020)

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Article Cardiac & Cardiovascular Systems

Comparison of interteukin-6, C-reactive protein, and low-density lipoprotein cholesterol as biomarkers of residual risk in contemporary practice: secondary analyses from the Cardiovascular Inflammation Reduction Trial

Paul M. Ridker et al.

EUROPEAN HEART JOURNAL (2020)

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Review Cardiac & Cardiovascular Systems

Fourth universal definition of myocardial infarction (2018)

Kristian Thygesen et al.

EUROPEAN HEART JOURNAL (2019)

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Article Cardiac & Cardiovascular Systems

Copeptin as a prognostic biomarker in acute myocardial infarction

Benoit Lattuca et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2019)

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Article Cardiac & Cardiovascular Systems

High cystatin C levels predict long-term mortality in patients with ST-segment elevation myocardial infarction undergoing late percutaneous coronary intervention: A retrospective study

Yuewu Chen et al.

CLINICAL CARDIOLOGY (2019)

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Article Medical Laboratory Technology

Prognostic role of GDF-15 across the spectrum of clinical risk in patients with NSTE-ACS

Thomas A. Zelniker et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2019)

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Article Cardiac & Cardiovascular Systems

Neuropeptide-Y causes coronary microvascular constriction and is associated with reduced ejection fraction following ST-elevation myocardial infarction

Neil Herring et al.

EUROPEAN HEART JOURNAL (2019)

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Article Medicine, General & Internal

Biomarker assessment for early infarct size estimation in ST-elevation myocardial infarction

Christina Tiller et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2019)

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Article Cardiac & Cardiovascular Systems

Soluble ST2 for Prediction of Clinical Outcomes in Patients with ST-Segment Elevation Myocardial Infarction Receiving Primary PCI

Xintian Liu et al.

INTERNATIONAL HEART JOURNAL (2019)

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Article Cardiac & Cardiovascular Systems

Remote ischemic perconditioning attenuates adverse cardiac remodeling and preserves left ventricular function in a rat model of reperfused myocardial infarction

Patrick M. Pilz et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2019)

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Article Urology & Nephrology

C-reactive protein velocity and the risk of acute kidney injury among ST elevation myocardial infarction patients undergoing primary percutaneous intervention

David Zahler et al.

JOURNAL OF NEPHROLOGY (2019)

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Article Medicine, General & Internal

Galectin-3 in Acute Myocardial Infarction Patients with Atrial Fibrillation

Dragana Stanojevic et al.

MEDICAL PRINCIPLES AND PRACTICE (2019)

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Article Medicine, Research & Experimental

Pretreatment with neuregulin-1 improves cardiac electrophysiological properties in a rat model of myocardial infarction

Panpan Rao et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2019)

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Article Biotechnology & Applied Microbiology

Endocan Is an Independent Predictor of Heart Failure-Related Mortality and Hospitalizations in Patients with Chronic Stable Heart Failure

Gorazd Kosir et al.

DISEASE MARKERS (2019)

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Article Cardiac & Cardiovascular Systems

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Increased Cystatin C Level in ST-Elevation Myocardial nfarction Predisposes the Prognosis of Angioplasty

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Elevated Baseline Serum Fibrinogen: Effect on 2-Year Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention

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Interleukin-6 and the Risk of Adverse Outcomes in Patients After an Acute Coronary Syndrome: Observations From the SOLID-TIMI 52 (Stabilization of Plaque Using Darapladib-Thrombolysis in Myocardial Infarction 52) Trial

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Usefulness of Mean Platelet Volume-to-Lymphocyte Ratio for Predicting Angiographic No-Reflow and Short-Term Prognosis After Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction

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Prognostic Value of Soluble ST2 After Myocardial Infarction: A Community Perspective

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ERBB signaling attenuates proinflammatory activation of nonclassical monocytes

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Normal platelet function

Michael Holinstat

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Serum neutrophil gelatinase-associated lipocalin has an advantage over serum cystatin C and glomerular filtration rate in prediction of adverse cardiovascular outcome in patients with ST-segment elevation myocardial infarction

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Correlations of serum cystatin C and glomerular filtration rate with vascular lesions and severity in acute coronary syndrome

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Association of serum transaminases with short- and long-term outcomes in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention

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BMC CARDIOVASCULAR DISORDERS (2017)

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Usefulness of Mean Platelet Volume to Predict Significant Coronary Artery Disease in Patients With Non-ST-Elevation Acute Coronary Syndromes

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Evaluation of the endothelial glycocalyx damage in patients with acute coronary syndrome

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Elevated serum fibrinogen levels and risk of contrast-induced acute kidney injury in patients undergoing a percutaneous coronary intervention for the treatment of acute coronary syndrome

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Catheter-based Intramyocardial Injection of FGF1 or NRG1-loaded MPs Improves Cardiac Function in a Preclinical Model of Ischemia-Reperfusion

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Circulating MicroRNA-146a and MicroRNA-21 Predict Left Ventricular Remodeling after ST-Elevation Myocardial Infarction

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HEART LUNG AND CIRCULATION (2014)

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Circulating miR-208b and miR-34a Are Associated with Left Ventricular Remodeling after Acute Myocardial Infarction

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Anti-Remodeling and Anti-Fibrotic Effects of the Neuregulin-1β Glial Growth Factor 2 in a Large Animal Model of Heart Failure

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Circulating cardio-enriched microRNAs are associated with long-term prognosis following myocardial infarction

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BMC CARDIOVASCULAR DISORDERS (2013)

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Circulating p53-Responsive MicroRNAs Are Predictive Indicators of Heart Failure After Acute Myocardial Infarction Short Communication

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MicroRNA-150 A Novel Marker of Left Ventricular Remodeling After Acute Myocardial Infarction

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Relationship of plasma neuropeptide Y with angiographic, electrocardiographic and coronary physiology indices of reperfusion during ST elevation myocardial infarction

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Uric acid in-hospital changes predict mortality in patients with acute myocardial infarction

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Correction: A Panel of 4 microRNAs Facilitates the Prediction of Left Ventricular Contractility after Acute Myocardial Infarction

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EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE (2013)

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Relation of circulating MicroRNA-133a concentrations with myocardial damage and clinical prognosis in ST-elevation myocardial infarction

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Prognostic Value of Uric Acid in Patients With ST-Elevated Myocardial Infarction Undergoing Primary Coronary Intervention

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A subset of circulating microRNAs are predictive for cardiac death after discharge for acute myocardial infarction

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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

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Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses

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EUROPEAN JOURNAL OF HEART FAILURE (2011)

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BASIC RESEARCH IN CARDIOLOGY (2005)

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