☆ 4.7 Review

Revisiting Regulated Cell Death Responses in Viral Infections

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis

Brienne A. McKenzie et al.

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Necroptosis and neutrophil-associated disorders

Xiaoliang Wang et al.

CELL DEATH & DISEASE (2018)

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Epstein-Barr virus encoded latent membrane protein 1 suppresses necroptosis through targeting RIPK1/3 ubiquitination

Xiaolan Liu et al.

CELL DEATH & DISEASE (2018)

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CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism

Jomnarong Lertsuwan et al.

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Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

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Cell-in-cell phenomena in cancer

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Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway

Cathleen Holze et al.

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Plasma membrane changes during programmed cell deaths

Yingying Zhang et al.

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Differences in T cell cytotoxicity and cell death mechanisms between progressive multifocal leukoencephalopathy, herpes simplex virus encephalitis and cytomegalovirus encephalitis

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Alarmins and Their Receptors as Modulators and Indicators of Alloimmune Responses

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Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

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Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

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Mouse cytomegalovirus M36 and M45 death suppressors cooperate to prevent inflammation resulting from antiviral programmed cell death pathways

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Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3

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Poxviruses Utilize Multiple Strategies to Inhibit Apoptosis

Daniel Brian Nichols et al.

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Induction of Apoptosis and Subsequent Phagocytosis of Virus-Infected Cells As an Antiviral Mechanism

Firzan Nainu et al.

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Gasdermin: A new player to the inflammasome game

Erivan S. Ramos et al.

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Entosis: The emerging face of non-cell-autonomous type IV programmed death

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Differential roles of caspase-1 and caspase-11 in infection and inflammation

Si Ming Man et al.

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Murine cytomegalovirus IE3-dependent transcription is required for DAI/ZBP1-mediated necroptosis

Haripriya Sridharan et al.

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Programmed cell death as a defence against infection

Ine Jorgensen et al.

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Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer

Anthony J. Berdis

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Targeting the lysosome in cancer

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Molecular mechanisms regulating NLRP3 inflammasome activation

Eun-Kyeong Jo et al.

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Inflammasome Complexes: Emerging Mechanisms and Effector Functions

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Dissecting How CD4 T Cells Are Lost During HIV Infection

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DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death

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Ferroptosis is an autophagic cell death process

Minghui Gao et al.

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GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

Lorenzo Sborgi et al.

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Inflammasomes and its importance in viral infections

Gaurav Shrivastava et al.

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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Xing Liu et al.

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Herpes Simplex Virus-1 Encephalitis in Adults: Pathophysiology, Diagnosis, and Management

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The interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathways

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Pranav Danthi

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Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death

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Herpes Simplex Virus Suppresses Necroptosis in Human Cells

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RIP1/RIP3 Binding to HSV-1 ICP6 Initiates Necroptosis to Restrict Virus Propagation in Mice

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In-cell infection: a novel pathway for Epstein-Barr virus infection mediated by cell-in-cell structures

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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

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Programmed Cell Death in Neurodevelopment

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Inflammasome signaling pathways exert antiviral effect against Chikungunya virus in human dermal fibroblasts

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Suppression of RIP3-dependent Necroptosis by Human Cytomegalovirus

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Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture

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Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice

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Necroptosis and its role in inflammation

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RIG-I in RNA virus recognition

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Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells

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Inflammasome control of viral infection

Christopher Lupfer et al.

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Methuosis Nonapoptotic Cell Death Associated with Vacuolization of Macropinosome and Endosome Compartments

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Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities

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RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction

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Necrosis-dependent and independent signaling of the RIP kinases in inflammation

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Staying Alive: Cell Death in Antiviral Immunity

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Inflammatory caspases are innate immune receptors for intracellular LPS

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Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

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Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Jose Pedro Friedmann Angeli et al.

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Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense

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IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV

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Recognition of Bacteria by Inflammasomes

Jakob von Moltke et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)

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Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

Jianfeng Wu et al.

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Targeting the viral Achilles' heel: recognition of 5′-triphosphate RNA in innate anti-viral defence

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The expanding role of NLRs in antiviral immunity

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Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

William J. Kaiser et al.

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Lysosomal cell death at a glance

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Epstein-Barr Virus-Encoded MicroRNA BART15-3p Promotes Cell Apoptosis Partially by Targeting BRUCE

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Reprogramming cellular events by poly(ADP-ribose)-binding proteins

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Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

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Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

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Reovirus Activates a Caspase-Independent Cell Death Pathway

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The lysosome: from waste bag to potential therapeutic target

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Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs)

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Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

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Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

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DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA

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Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1

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Plasmacytoid Dendritic Cells (pDCs) From HIV Controllers Produce Interferon-α and Differentiate Into Functional Killer pDCs Under HIV Activation

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Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

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Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein

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Fueling the Flames: Mammalian Programmed Necrosis in Inflammatory Diseases

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The ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 protect cells against TNFα- and FasL-induced apoptosis by interacting with caspase-8

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APOPTOSIS (2011)

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Activation of Cell Death Mediated by Apoptosis-Inducing Factor Due to the Absence of Poly(ADP-ribose) Glycohydrolase

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Programmed Cell Death in Animal Development and Disease

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Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis

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IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection

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Molecular mechanisms of inflammasome activation during microbial infections

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Coordinated Host Responses during Pyroptosis: Caspase-1-Dependent Lysosome Exocytosis and Inflammatory Cytokine Maturation

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A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells

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Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis

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Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

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Interplay between Innate Immunity and Negative-Strand RNA Viruses: towards a Rational Model

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PAD4-Mediated Neutrophil Extracellular Trap Formation Is Not Required for Immunity against Influenza Infection

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The inflammasomes: molecular effectors of host resistance against bacterial, viral, parasitic, and fungal infections

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Endonuclease G does not play an obligatory role in poly(ADP-ribose) polymerase-dependent cell death after transient focal cerebral ischemia

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Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

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Virus Inhibition of RIP3-Dependent Necrosis

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Characterization of neutrophil extracellular traps in cats naturally infected with feline leukemia virus

Amanda B. Wardini et al.

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The Rubella Virus Capsid Protein Inhibits Mitochondrial Import

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Induction of Nonapoptotic Cell Death by Activated Ras Requires Inverse Regulation of Rac1 and Arf6

Haymanti Bhanot et al.

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The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

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Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

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Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry

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Parthanatos, a messenger of death

Karen Kate David et al.

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The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

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Reduced serum hepcidin levels in patients with chronic hepatitis C

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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

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Pyroptosis: host cell death and inflammation

Tessa Bergsbaken et al.

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Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

Paul Saftig et al.

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HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

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Mitochondrial and Nuclear Cross Talk in Cell Death Parthanatos

Shaida A. Andrabi et al.

MITOCHONDRIA AND OXIDATIVE STRESS IN NEURODEGENERATIVE DISORDERS (2008)

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Cytomegalovirus m45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1

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Active Ras triggers death in glioblastoma cells through hyperstimulation of macropinocytosis

Jean H. Overmeyer et al.

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The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

Daniel A. Muruve et al.

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Viral infection and iron metabolism

Hal Drakesmith et al.

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Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

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Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

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Advances in neuronal cell death 2007

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A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion

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Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members

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Hepatic iron accumulation is associated with disease progression and resistance to interferon/ribavirin combination therapy in chronic hepatitis C

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Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia

Changlian Zhu et al.

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Cardiolipin switch in mitochondria:: Shutting off the reduction of cytochrome c and turning on the peroxidase activity

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Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

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Hepcidin expression in the liver: Relatively low level in patients with chronic hepatitis C

Naoki Fujita et al.

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Apoptosis: A review of programmed cell death

Susan Elmore

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Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

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Poly(ADP-ribose) (PAR) polymer is a death signal

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

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Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

Susan L. Fink et al.

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Mitochondrial membrane permeability transition and cell death

Yoshihide Tsujimoto et al.

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Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

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EndoG is dispensable in embryogenesis and apoptosis

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CELL DEATH AND DIFFERENTIATION (2006)

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Differential expression of IFN-α and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

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Anti-immunology: Evasion of the host immune system by bacterial and viral pathogens

BB Finlay et al.

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Mechanisms of cytochrome c release from mitochondria

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A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection

JB Johnston et al.

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Another way to die: autophagic programmed cell death

Y Tsujimoto et al.

CELL DEATH AND DIFFERENTIATION (2005)

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Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells

SL Fink et al.

INFECTION AND IMMUNITY (2005)

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Influenza A mutant viruses with altered NS1 protein function provoke caspase-1 activation in primary human macrophages, resulting in fast apoptosis and release of high levels of interleukins 1 beta and 18

J Stasakova et al.

JOURNAL OF GENERAL VIROLOGY (2005)

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Article Biochemistry & Molecular Biology

AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis

C Candé et al.

ONCOGENE (2004)

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Article Immunology

HIV-1 cell to cell transfer across an env-induced, actin-dependent synapse

C Jolly et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2004)

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Article Immunology

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

M Yoneyama et al.

NATURE IMMUNOLOGY (2004)

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Article Virology

Differential function and expression of the viral inhibitor of caspase 8-induced apoptosis (vICA) and the viral mitochondria-localized inhibitor of apoptosis (vMIA) cell death suppressors conserved in primate and rodent cytomegaloviruses

AL McCormick et al.

VIROLOGY (2003)

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Article Cell Biology

Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli

D Arnoult et al.

JOURNAL OF CELL BIOLOGY (2002)

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Article Biochemistry & Molecular Biology

Initiator caspases in apoptosis signaling pathways

M Chen et al.

APOPTOSIS (2002)

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Article Biochemistry & Molecular Biology

The inflammasome:: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β

F Martinon et al.

MOLECULAR CELL (2002)

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Article Multidisciplinary Sciences

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

SW Yu et al.

SCIENCE (2002)

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Article Biochemistry & Molecular Biology

Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3

XQ Sun et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

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Review Pathology

Viruses and apoptosis

BJ Thomson

INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2001)

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Article Biochemistry & Molecular Biology

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

JL Poyet et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

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Article Biochemistry & Molecular Biology

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

A Krueger et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

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Review Biochemistry & Molecular Biology

The world according to PARP

S Smith

TRENDS IN BIOCHEMICAL SCIENCES (2001)

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Article Multidisciplinary Sciences

A ribonucleotide reductase homolog of cytomegalovirus and endothelial cell tropism

W Brune et al.

SCIENCE (2001)

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Review Cardiac & Cardiovascular Systems

Morphologic and biochemical hallmarks of apoptosis

A Saraste et al.

CARDIOVASCULAR RESEARCH (2000)

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