4.7 Review

Purinergic Signaling in Oral Tissues

Related references

Note: Only part of the references are listed.
Article Nanoscience & Nanotechnology

Periodontal Ligament Stem Cell-Derived Small Extracellular Vesicles Embedded in Matrigel Enhance Bone Repair Through the Adenosine Receptor Signaling Pathway

Bingjiao Zhao et al.

Summary: This study demonstrates for the first time that P-EVs accelerate bone defect repair through promoting cell proliferation and migration. The combination of local EV implantation and extracellular matrix scaffolds, known as P-EV/Matrigel, provides a novel cell-free strategy for bone tissue repair.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2022)

Review Pharmacology & Pharmacy

Adenosine and inflammation: it's time to (re)solve the problem

Luca Antonioli et al.

Summary: The adenosine system plays a crucial role in resolving inflammation by regulating inflammatory cell activity for an effective transition. Pharmacological strategies based on the adenosine system have opened up a new area of research in resolving inflammation.

TRENDS IN PHARMACOLOGICAL SCIENCES (2022)

Article Biology

The Role of Connexin Hemichannels in Inflammatory Diseases

Bo Peng et al.

Summary: This article provides an updated view of the role of connexin hemichannels in inflammatory diseases, as well as the progress in developing selective blockers for these channels. Opening of connexin hemichannels promotes inflammation, while blockade of these channels leads to reduced inflammation, tissue injury and improved organ function.

BIOLOGY-BASEL (2022)

Article Biochemistry & Molecular Biology

Signalling by extracellular nucleotides in health and disease

Valentina Vultaggio-Poma et al.

Summary: Nucleotides play crucial roles in cell biology, particularly in the nervous system and disease pathogenesis.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2022)

Review Biochemistry & Molecular Biology

Mesenchymal Stem Cells Based Treatment in Dental Medicine: A Narrative Review

Igor Smojver et al.

Summary: The application of mesenchymal stem cells (MSC) in regenerative dentistry is gaining importance. Dental tissue-derived MSCs have characteristics such as multidifferentiation potential, self-renewal capacity, and easy accessibility, making them key players in stem cell-based therapy. Different types of dental stem cells have been discovered and their potential usage is found in various branches of dentistry as well as other medical fields. This review focuses on dental MSC sources and their treatment modalities, with a specific emphasis on temporomandibular joint osteoarthritis (TMJ OA).

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Review Pharmacology & Pharmacy

International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update

Adriaan P. IJzerman et al.

Summary: This review provides an update on the nomenclature and classification of adenosine receptors, with a focus on emerging developments in protein structure, diversity, and modulation by small molecules. It also explores novel concepts such as target binding kinetics and biased signaling, as well as discusses the clinical trials and pharmacology of adenosine receptor ligands.

PHARMACOLOGICAL REVIEWS (2022)

Review Biochemistry & Molecular Biology

Structure-activity features of purines and their receptors: implications in cell physiopathology

Mauricio Diaz-Munoz et al.

Summary: The purine molecular structure plays important roles in nucleic acids, cell communication, metabolism, immune response, and energy homeostasis. It functions as chemical messengers, antioxidants, and anti-inflammatory agents. Imbalances in purine levels can compromise cellular stability and survival.

MOLECULAR BIOMEDICINE (2022)

Review Dentistry, Oral Surgery & Medicine

Dental nerves: a neglected mediator of pulpitis

C. Zhan et al.

Summary: Dental nerves play crucial roles in tooth pain induction, sensitization, and maintenance, as well as regulating non-neuronal cells and immune responses. They are also involved in the repair of dental soft and hard tissues, highlighting their importance in pulpitis and potential implications for endodontic treatment.

INTERNATIONAL ENDODONTIC JOURNAL (2021)

Review Physiology

Taste transduction and channel synapses in taste buds

Akiyuki Taruno et al.

Summary: Recent research has made significant progress in understanding the molecular mechanisms behind taste transduction, including the identification of specific taste sensors and components for each taste sensation. The discovery of unconventional chemical synapses and insights into the structures of ion channels have provided new perspectives in the field of taste sensation and neurotransmission.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2021)

Review Pharmacology & Pharmacy

Purinergic receptors in airway hydration

Eduardo R. Lazarowski et al.

Summary: In healthy airways, purinergic receptors in airway epithelial cells regulate mucociliary clearance by controlling mucus hydration, and abnormal hydration can lead to mucus accumulation, which is a major contributing factor to the progression of chronic lung diseases.

BIOCHEMICAL PHARMACOLOGY (2021)

Review Pharmacology & Pharmacy

Purinergic signalling in the kidney: In physiology and disease

Marie-Louise T. Monaghan et al.

Summary: Historically, renal vascular and tubular function has been mainly controlled through neural and endocrine regulation. However, it is now acknowledged that complex humoral control systems exist within the kidney, complementing neuroendocrine regulation by fine-tuning renal function in response to rapid changes. The extracellular nucleotide/P2 receptor system plays a central role in intrinsic regulatory feedback loops within the kidney, contributing to the understanding and potential treatment of kidney disease.

BIOCHEMICAL PHARMACOLOGY (2021)

Review Pharmacology & Pharmacy

Purinergic signaling in diabetes and metabolism

Shanu Jain et al.

Summary: Purinergic signaling, originally proposed by Geoffrey Burnstock, plays a crucial role in modulating pathways in various physiological systems. Adenosine receptors and P2 nucleotide receptors are involved in metabolic disorders, affecting specific cell types like adipocytes, skeletal muscle, liver cells, and immune cells. Selective ligands for adenosine and P2 receptors may have therapeutic potential for diabetes and obesity, but conflicting conclusions exist in drug discovery related to this topic.

BIOCHEMICAL PHARMACOLOGY (2021)

Article Neurosciences

Purinergic neurotransmission in the gustatory system

T. Finger et al.

Summary: Taste buds are made up of specialized epithelial cells that detect specific tastants and release ATP as a neurotransmitter onto nerve fibers. Despite recent discoveries, there are still several aspects of purinergic transmission in the taste system that need further elucidation.

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2021)

Review Pharmacology & Pharmacy

Update of P2X receptor properties and their pharmacology: IUPHAR Review 30

Peter Illes et al.

Summary: P2X receptors are cationic channels consisting of seven different subunits, with researchers having determined their structure and function. In addition, primitive ligand-gated counterparts related to P2X receptors have been cloned, and various selective antagonists have been discovered.

BRITISH JOURNAL OF PHARMACOLOGY (2021)

Review Chemistry, Multidisciplinary

Toward a Molecular Basis of Cellular Nucleoside Transport in Humans

Nicholas J. Wright et al.

Summary: Nucleosides, essential in various life processes, rely on specific transport systems to cross biological membranes. Humans have two unrelated protein families mediating nucleoside membrane transport. This review provides an overview of nucleoside transport research, focusing on their roles in human health, recent structural advancements, and pharmacological features.

CHEMICAL REVIEWS (2021)

Review Microbiology

P2RX7 at the Host-Pathogen Interface of Infectious Diseases

Alexandra Y. Soare et al.

Summary: P2X7 receptors play important roles in immune response to various pathogens, mediating and modulating immune responses in different cell types. Their signaling is critical in perceiving damage-associated molecular patterns released by infected cells and facilitating immune responses.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2021)

Review Biochemistry & Molecular Biology

Release mechanisms of major DAMPs

Atsushi Murao et al.

Summary: Damage-associated molecular patterns (DAMPs) are endogenous molecules associated with inflammation and diseases, and studying their release mechanisms and therapeutic strategies is crucial.

APOPTOSIS (2021)

Review Neurosciences

Purinergic signaling in peripheral nervous system glial cells

Jennifer Patritti-Cram et al.

Summary: Purinergic receptor activation plays a crucial role in peripheral nerve development and disease, regulating SC proliferation and differentiation, as well as the development of nerve tumors and neuropathies.
Article Dentistry, Oral Surgery & Medicine

P2Y2 receptor antagonism resolves sialadenitis and improves salivary flow in a Sjogren's syndrome mouse model

Kimberly J. Jasmer et al.

Summary: The P2Y(2)R antagonist AR-C118925 significantly enhances salivation and reduces lymphocytic foci and immune cell markers in SMGs of NOD.H-2(h4) DKO mice with SS. B cells are the primary immune cell population in inflamed SMGs expressing elevated levels of P2Y(2)R.

ARCHIVES OF ORAL BIOLOGY (2021)

Review Cardiac & Cardiovascular Systems

Adenosine and adenosine receptor-mediated action in coronary microcirculation

Ying Zhang et al.

Summary: Adenosine is a crucial extracellular signaling molecule that regulates coronary microcirculation through activation of adenosine receptors. Its balance between intra- and extracellular compartments is maintained by various enzymes and nucleoside transporters. Adenosine-mediated coronary microvascular tone and reactive hyperemia mainly involve A(2A)R activation and downstream stimulation of channels, contributing to coronary vasodilation.

BASIC RESEARCH IN CARDIOLOGY (2021)

Article Physiology

Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation

Aya Yamada et al.

Summary: Connexin 43 (Cx43) is an integral membrane protein that plays a crucial role in tooth development, regulating intercellular communication through gap junction activity by modulating TGF-beta 1-mediated ERK signaling and enamel formation.

FRONTIERS IN PHYSIOLOGY (2021)

Review Endocrinology & Metabolism

Purine metabolites and complex diseases: role of genes and nutrients

Kendra L. Nelson et al.

Summary: Purines play important roles in complex diseases and their impact is still being uncovered. Uric acid, as the most studied purine metabolite, has dual roles in disease pathogenesis. Other purines like adenosine and inosine have neuroprotective properties valuable in neurodegenerative diseases. Further studies are needed to fully understand the relevance of purines in complex diseases.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2021)

Review Dentistry, Oral Surgery & Medicine

Disease-Induced Changes in Salivary Gland Function and the Composition of Saliva

G. B. Proctor et al.

Summary: Although the physiological control of salivary secretion has been well studied, the impact of disease on salivary gland function and how this changes the composition and function of saliva is less well understood. Longer-term changes in saliva secretion have been found to occur in response to dietary change and aging, and these physiological influences can alter the composition and function of saliva in the mouth.

JOURNAL OF DENTAL RESEARCH (2021)

Review Cell Biology

Salivary Biomarkers of Oxidative Stress and Inflammation in Stroke Patients: From Basic Research to Clinical Practice

Mateusz Maciejczyk et al.

Summary: Cerebral stroke is a global health issue. Diagnosis is currently based on neurological examination and medical history. Oxidative stress and inflammation play key roles in stroke pathogenesis, and saliva could be a new method for diagnosis and prognosis.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)

Article Biochemistry & Molecular Biology

Control Release of Adenosine Potentiate Osteogenic Differentiation within a Bone Integrative EGCG-g-NOCC/Collagen Composite Scaffold toward Guided Bone Regeneration in a Critical-Sized Calvarial Defect

Neeraj K. Verma et al.

Summary: This study developed an optimized osteogenic scaffold, AD/EGCG-g-NOCC@clgn I, which stimulated MSCs towards osteoblast differentiation and promoted swift bone regeneration in calvarial defects in mice. The 3D matrix provided a favorable microenvironment and structural support for accelerated bone formation and union.

BIOMACROMOLECULES (2021)

Review Endocrinology & Metabolism

Purinergic Signaling in Liver Pathophysiology

Shanu Jain et al.

Summary: Research has shown that purinergic receptors play a vital role in regulating liver function and the development of liver diseases, suggesting potential therapeutic strategies by targeting adenosine, P2Y, and P2X receptors.

FRONTIERS IN ENDOCRINOLOGY (2021)

Review Biochemistry & Molecular Biology

Exocytosis in Astrocytes

Aleksandra Mielnicka et al.

Summary: Astrocytes, once considered simple brain glue, have been found to be dynamic partners involved in brain metabolism and influencing communication between neurons. Their communication with neurons is diverse, with regulated exocytosis receiving the most attention. Astrocytes possess complex vesicular organelles and molecular mechanisms that regulate exocytosis.

BIOMOLECULES (2021)

Article Microbiology

Differential involvement of the canonical and noncanonical inflammasomes in the immune response against infection by the periodontal bacteria Porphyromonas gingivalis and Fusobacterium nucleatum

Kivia Queiroz De Andrade et al.

Summary: This study demonstrated the involvement of the P2 x7-caspase-1 and caspase-11 pathways in the immune response against infection by periodontal bacteria, Porphyromonas gingivalis and Fusobacterium nucleatum, respectively.

CURRENT RESEARCH IN MICROBIAL SCIENCES (2021)

Review Biochemistry & Molecular Biology

From purines to purinergic signalling: molecular functions and human diseases

Zhao Huang et al.

Summary: Purines, such as adenosine and ATP, play crucial roles in controlling intracellular energy homeostasis and nucleotide synthesis, as well as regulating cell behavior through purinergic signaling. Pathological deregulation of purinergic signaling is associated with various diseases, making purinoceptors potential therapeutic targets.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

Article Dentistry, Oral Surgery & Medicine

Association of P2RX7 functional variants with localized aggressive periodontitis

Theodore H. Harris et al.

JOURNAL OF PERIODONTAL RESEARCH (2020)

Article Pharmacology & Pharmacy

Update of P2Y Receptor Pharmacology: IUPHAR Review:27

Kenneth A. Jacobson et al.

BRITISH JOURNAL OF PHARMACOLOGY (2020)

Review Pharmacology & Pharmacy

Approaches for designing and discovering purinergic drugs for gastrointestinal diseases

Diego Dal Ben et al.

EXPERT OPINION ON DRUG DISCOVERY (2020)

Review Pharmacology & Pharmacy

P2 Receptors as Therapeutic Targets in the Salivary Gland: From Physiology to Dysfunction

Mahmoud G. Khalafalla et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Biochemistry & Molecular Biology

Extracellular ATP as an Inter-Kingdom Signaling Molecule: Release Mechanisms by Bacteria and Its Implication on the Host

Daniel Spari et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Cell Biology

Insight into Salivary Gland Aquaporins

Claudia D'Agostino et al.

CELLS (2020)

Review Medicine, General & Internal

Radiation-Induced Salivary Gland Dysfunction: Mechanisms, Therapeutics and Future Directions

Kimberly J. Jasmer et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Review Cell Biology

Extracellular ATP: A Feasible Target for Cancer Therapy

Valentina Vultaggio-Poma et al.

CELLS (2020)

Review Biochemistry & Molecular Biology

Hedgehog Signaling Regulates Taste Organs and Oral Sensation: Distinctive Roles in the Epithelium, Stroma, and Innervation

Charlotte M. Mistretta et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Dentistry, Oral Surgery & Medicine

Purinergic Signaling Modulates Survival/Proliferation of Human Dental Pulp Stem Cells

S. Zhang et al.

JOURNAL OF DENTAL RESEARCH (2019)

Article Physiology

P2X7 receptor deletion suppresses γ-radiation-induced hyposalivation

Kristy E. Gilman et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2019)

Article Anatomy & Morphology

Periostin, dentin matrix protein 1 and P2rx7 ion channel in human teeth and periodontal ligament

I. Menendez-Diaz et al.

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER (2018)

Article Dentistry, Oral Surgery & Medicine

Histamine stimulates secretion of extracellular vesicles with nucleotidase activity in rat submandibular gland

Debora Alejandra Gonzalez et al.

ARCHIVES OF ORAL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Adenosine receptors enhance the ATP-induced odontoblastic differentiation of human dental pulp cells

Xiaosong Yi et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Article Medicine, Research & Experimental

Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement

Elaine Emmerson et al.

EMBO MOLECULAR MEDICINE (2018)

Article Biochemistry & Molecular Biology

Autoantibodies against muscarinic acetylcholine receptor M3 in Sjogren's syndrome and corresponding mouse models

Xinhua Yu et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2018)

Review Biochemistry & Molecular Biology

Unfolding Role of a Danger Molecule Adenosine Signaling in Modulation of Microbial Infection and Host Cell Response

Jaden S. Lee et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Dentistry, Oral Surgery & Medicine

P2Y2R deletion ameliorates sialadenitis in IL-14-transgenic mice

L. T. Woods et al.

ORAL DISEASES (2018)

Article Dentistry, Oral Surgery & Medicine

Extracellular ATP Induces Calcium Signaling in Odontoblasts

B. M. Lee et al.

JOURNAL OF DENTAL RESEARCH (2017)

Article Dentistry, Oral Surgery & Medicine

Genetic determinants and postorthodontic external apical root resorption in Czech children

P. Borilova Linhartova et al.

ORAL DISEASES (2017)

Article Dentistry, Oral Surgery & Medicine

CD73 Controls Extracellular Adenosine Generation in the Trigeminal Nociceptive Nerves

X. Liu et al.

JOURNAL OF DENTAL RESEARCH (2017)

Article Dentistry, Oral Surgery & Medicine

Role of Piezo Channels in Ultrasound-stimulated Dental Stem Cells

Qianhua Gao et al.

JOURNAL OF ENDODONTICS (2017)

Review Biochemistry & Molecular Biology

Vesicular nucleotide transporter (VNUT): appearance of an actress on the stage of purinergic signaling

Yoshinori Moriyama et al.

PURINERGIC SIGNALLING (2017)

Article Dentistry, Oral Surgery & Medicine

Theophylline increases saliva sonic hedgehog and improves taste dysfunction

Robert I. Henkin et al.

ARCHIVES OF ORAL BIOLOGY (2017)

Review Dentistry, Oral Surgery & Medicine

Extracellular ATP is a key modulator of alveolar bone loss in periodontitis

Itzhak Binderman et al.

ARCHIVES OF ORAL BIOLOGY (2017)

Review Dentistry, Oral Surgery & Medicine

The physiology of salivary secretion

Gordon B. Proctor

PERIODONTOLOGY 2000 (2016)

Article Cell Biology

Expression of Vesicular Nucleotide Transporter in Rat Odontoblasts

Erina Ikeda et al.

ACTA HISTOCHEMICA ET CYTOCHEMICA (2016)

Article Medicine, Research & Experimental

P2Y purinoceptors mediate ATP-induced changes in intracellular calcium and amylase release in acinar cells of mouse parotid glands

Kasumi Moriguchi-Mori et al.

BIOMEDICAL RESEARCH-TOKYO (2016)

Article Dentistry, Oral Surgery & Medicine

Effects of Adenosine Triphosphate on Proliferation and Odontoblastic Differentiation of Human Dental Pulp Cells

Wei Wang et al.

JOURNAL OF ENDODONTICS (2016)

Review Neurosciences

ADENOSINE RECEPTOR TARGETS FOR PAIN

J. Sawynok

NEUROSCIENCE (2016)

Review Immunology

Purinergic Signaling During Immune Cell Trafficking

Davide Ferrari et al.

TRENDS IN IMMUNOLOGY (2016)

Article Dentistry, Oral Surgery & Medicine

Growth characteristics and expression of CD73 and CD146 in cells cultured from dental pulp

Vaishnavi Sivasankar et al.

JOURNAL OF INVESTIGATIVE AND CLINICAL DENTISTRY (2016)

Article Dentistry, Oral Surgery & Medicine

A Dual Role for P2X7 Receptor during Porphyromonas gingivalis Infection

E. S. Ramos-Junior et al.

JOURNAL OF DENTAL RESEARCH (2015)

Article Neurosciences

Expression and function of purinergic P2Y12 receptors in rat trigeminal ganglion neurons

Aya Kawaguchi et al.

NEUROSCIENCE RESEARCH (2015)

Review Biochemistry & Molecular Biology

The role of purinergic receptors in stem cell differentiation

Constanze Kaebisch et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2015)

Article Biochemistry & Molecular Biology

Rat submandibular glands secrete nanovesicles with NTPDase and 5'-nucleotidase activities

Debora A. Gonzalez et al.

PURINERGIC SIGNALLING (2015)

Review Biochemistry & Molecular Biology

Enzymes involved in metabolism of extracellular nucleotides and nucleosides: Functional implications and measurement of activities

Gennady G. Yegutkin

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2014)

Review Physiology

Purinergic signalling: from discovery to current developments

Geoffrey Burnstock

EXPERIMENTAL PHYSIOLOGY (2014)

Article Cell Biology

Expression of adenosine A2b receptor in rat type II and III taste cells

Kentaro Nishida et al.

HISTOCHEMISTRY AND CELL BIOLOGY (2014)

Article Dentistry, Oral Surgery & Medicine

Polymorphisms of genes encoding P2X7R, IL-1B, OPG and RANK in orthodontic-induced apical root resorption

S. Pereira et al.

ORAL DISEASES (2014)

Article Dentistry, Oral Surgery & Medicine

Gravity loading induces adenosine triphosphate release and phosphorylation of extracellular signal-regulated kinases in human periodontal ligament cells

Mai Ito et al.

JOURNAL OF INVESTIGATIVE AND CLINICAL DENTISTRY (2014)

Review Pharmacology & Pharmacy

Purinergic Signaling and Blood Vessels in Health and Disease

Geoffrey Burnstock et al.

PHARMACOLOGICAL REVIEWS (2014)

Article Multidisciplinary Sciences

Role of the ectonucleotidase NTPDase2 in taste bud function

Aurelie Vandenbeuch et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Cell Biology

P2X7 receptor activation induces inflammatory responses in salivary gland epithelium

Lucas T. Woods et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2012)

Article Biochemistry & Molecular Biology

Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids

Mikko Helenius et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)

Article Dentistry, Oral Surgery & Medicine

Expression of Ecto-ATPase NTPDase2 in Human Dental Pulp

X. Liu et al.

JOURNAL OF DENTAL RESEARCH (2012)

Review Dentistry, Oral Surgery & Medicine

Inflammation, Pain, and Pressure-Purinergic Signaling in Oral Tissues

J. C. Lim et al.

JOURNAL OF DENTAL RESEARCH (2012)

Review Biochemistry & Molecular Biology

Vesicular and conductive mechanisms of nucleotide release

Eduardo R. Lazarowski

PURINERGIC SIGNALLING (2012)

Article Gastroenterology & Hepatology

Ectonucleotidases in the digestive system: focus on NTPDase3 localization

Elise G. Lavoie et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2011)

Article Dentistry, Oral Surgery & Medicine

Purine nucleoside phosphorylase activity and expression are upregulated in sites affected by periodontal disease

E. L. Batista et al.

JOURNAL OF PERIODONTAL RESEARCH (2010)

Article Biochemistry & Molecular Biology

Identification of the vesicular nucleotide transporter (VNUT) in taste cells

Ken Iwatsuki et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Article Biochemistry & Molecular Biology

Purinergic P2X7 Receptors Mediate ATP-induced Saliva Secretion by the Mouse Submandibular Gland

Tetsuji Nakamoto et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Prostatic acid phosphatase, a neglected ectonucleotidase

Herbert Zimmermann

PURINERGIC SIGNALLING (2009)

Article Physiology

Involvement of apical P2Y2 receptor-regulated CFTR activity in muscarinic stimulation of Cl- reabsorption in rat submandibular gland

Kazunari Ishibashi et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2008)

Review Biochemistry & Molecular Biology

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

Gennady G. Yegutkin

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)

Review Biochemistry & Molecular Biology

Purine and pyrimidine receptors

G. Burnstock

CELLULAR AND MOLECULAR LIFE SCIENCES (2007)

Article Dentistry, Oral Surgery & Medicine

P2X4 is up-regulated in gingival fibroblasts after periodontal surgery

I. Binderman et al.

JOURNAL OF DENTAL RESEARCH (2007)

Article Neurosciences

Nucleoside triphosphate diphosphohydrolase-2 is the ecto-ATPase of type I cells in taste buds

Dianna L. Bartel et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2006)

Article Dentistry, Oral Surgery & Medicine

Differential coupling of the P2Y1 receptor to Gα14 and Gαq/11 proteins during the development of the rat salivary gland

Olga J. Baker et al.

ARCHIVES OF ORAL BIOLOGY (2006)

Article Multidisciplinary Sciences

ATP signaling is crucial for communication from taste buds to gustatory nerves

TE Finger et al.

SCIENCE (2005)

Article Dentistry, Oral Surgery & Medicine

P2Y2 nucleotide receptor up-regulation in submandibular gland cells from the NOD.B10 mouse model of Sjogren's syndrome

AM Schrader et al.

ARCHIVES OF ORAL BIOLOGY (2005)

Review Developmental Biology

Friedrich Miescher and the discovery of DNA

R Dahm

DEVELOPMENTAL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

CAMP potentiates ATP-evoked calcium signaling in human parotid acinar cells

DA Brown et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Physiology

Molecular physiology of P2X receptors

RA North

PHYSIOLOGICAL REVIEWS (2002)

Article Chemistry, Medicinal

Ectonucleotidases: Some recent developments and a note on nomenclature

H Zimmermann

DRUG DEVELOPMENT RESEARCH (2001)

Article Cell Biology

Reversible regulation of P2Y2 nucleotide receptor expression in the duct-ligated rat submandibular gland

JS Ahn et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2000)