4.7 Review

A Guide to Polysaccharide-Based Hydrogel Bioinks for 3D Bioprinting Applications

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

A New Printable Alginate/Hyaluronic Acid/Gelatin Hydrogel Suitable for Biofabrication of In Vitro and In Vivo Metastatic Melanoma Models

Rafael Schmid et al.

Summary: In recent years, 3D cancer models have shown greater application potential in drug development, especially in simulating the tumor microenvironment and studying melanoma progression.

ADVANCED FUNCTIONAL MATERIALS (2022)

Review Chemistry, Multidisciplinary

Chitosan-based inks for 3D printing and bioprinting

Mohsen Taghizadeh et al.

Summary: The introduction of 3D printing/bioprinting techniques in the biomedical engineering field has revolutionized the preparation of biomimetic structures and accelerated progress in regenerative medicine. Smart bio-inks are being developed to facilitate the creation of complex and homogeneous living-cell-containing 3D constructs. Challenges and restrictions of chitosan bio-inks are highlighted, along with potential for 4D bioprinting of engineered tissues and artificial organs using smart inks based on chitosan.

GREEN CHEMISTRY (2022)

Article Biochemistry & Molecular Biology

An osteogenic bioink composed of alginate, cellulose nanofibrils, and polydopamine nanoparticles for 3D bioprinting and bone tissue engineering

Seunghyun Im et al.

Summary: Bioprinting is an emerging technology for manufacturing cell-laden 3D scaffolds to support cell growth and differentiation. This study formulated various nanocomposite hydrogel-based bioinks using natural and biocompatible biomaterials and found that a bioink containing 1.5% alginate and 1.5% TOCNF, with or without 0.5% PDANP, demonstrated suitable printability for 3D printing and induced significant osteogenesis in vitro.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Review Biochemistry & Molecular Biology

Advance research in biomedical applications on marine sulfated polysaccharide

Mary Shamya Arokiarajan et al.

Summary: Marine ecosystem associated organisms are a rich source of bioactive compounds, particularly polysaccharides, which have gained significant interest in the biomedical field. Seaweeds are particularly noted for their natural bioactive sulfated polysaccharides, with a wide range of therapeutic applications including antitumor and immunomodulatory properties.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Article Biochemistry & Molecular Biology

Tethered TGF-β1 in a Hyaluronic Acid-Based Bioink for Bioprinting Cartilaginous Tissues

Julia Hauptstein et al.

Summary: In this study, a hyaluronic acid-based bioink was developed that allowed for the covalent tethering of TGF-beta 1, a growth factor important for cartilage regeneration. The functionality of the tethered TGF-beta 1 was successfully demonstrated in promoting chondrogenesis and maintaining its activity after 3D printing.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Biochemistry & Molecular Biology

3D Bioprinting of Gelatin-Xanthan Gum Composite Hydrogels for Growth of Human Skin Cells

Beatrice Piola et al.

Summary: In this study, a crosslinked 3D printable hydrogel based on gelatin and xanthan gum was developed for use as a scaffold for cell growth and as a wound dressing. These hydrogels showed different porosity and degradation time and exhibited biocompatibility.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Biochemistry & Molecular Biology

Bioink Platform Utilizing Dual-Stage Crosslinking of Hyaluronic Acid Tailored for Chondrogenic Differentiation of Mesenchymal Stromal Cells

Julia Hauptstein et al.

Summary: A new bioink platform using thiolated hyaluronic acid (HA-SH) enables effective 3D printing and chondrogenesis. By utilizing a dual-stage crosslinking approach with HA-SH of varying molecular weights, the bioink not only maintains printability but also significantly enhances the quality and stiffness of cultured constructs.

MACROMOLECULAR BIOSCIENCE (2022)

Review Materials Science, Biomaterials

3D bioprinting and photocrosslinking: emerging strategies & future perspectives

Allen Zennifer et al.

Summary: 3D bioprinting technology enables the creation of biomimetic tissue constructs and in vitro model systems, and photo-crosslinking is an elegant technique for precise control of gelation during bioprinting. This article summarizes the application of photo-crosslinking agents and methods in optimizing 3D constructs, and discusses the challenges and new directions in 3D bioprinting.

BIOMATERIALS ADVANCES (2022)

Review Biochemistry & Molecular Biology

Natural Polymers-Based Materials: A Contribution to a Greener Future

Ana C. Q. Silva et al.

Summary: This review highlights the research efforts conducted by the BioPol4fun research team at the CICECO-Aveiro Institute of Materials, University of Aveiro, on the exploitation of natural polymers and their derivatives for the development of sustainable biobased materials. The focus is on the use of polysaccharides and proteins for various applications.

MOLECULES (2022)

Review Chemistry, Applied

Carrageenans for tissue engineering and regenerative medicine applications: A review

Arman Jafari et al.

Summary: Biomaterials play a crucial role in tissue engineering, regenerative medicine, and drug delivery, with polymeric biomaterials being the most promising candidates. Carrageenan, derived from red seaweed, possesses unique properties and various biological activities, making it highly attractive for tissue engineering and drug delivery research.

CARBOHYDRATE POLYMERS (2022)

Article Cell & Tissue Engineering

Myoblast 3D bioprinting to burst in vitro skeletal muscle differentiation

Flavio L. Ronzoni et al.

Summary: This study compares the effects of different hydrogels on the viability, proliferation, and differentiation of myoblasts in 3D bioprinted constructs and finds that using NFC/alginate-fibrinogen-based hydrogel yields the best results after 7-14 days of culture.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2022)

Article Polymer Science

Characterization of κ-carrageenan/methylcellulose/cellulose nanocrystal hydrogels for 3D bioprinting

Wannisa Boonlai et al.

Summary: Bioinks composed of KC and MC were used for extrusion-based bioprinting, with enhanced physical and mechanical properties achieved through ionic crosslinking and the addition of CNC nanocrystals. The presence of CNC improved shear thinning and thixotropic behavior, leading to better printability and higher compressive mechanical properties. Good cell viability was observed for 3D bioprinted constructs, indicating the potential of the novel hydrogel for bioprinting applications.

POLYMER INTERNATIONAL (2022)

Article Materials Science, Multidisciplinary

Geometrical control of degradation and cell delivery in 3D printed nanocellulose hydrogels

Rupambika Das et al.

Summary: Hydrogels based on cellulose nanofibers have gained attention in biomedical applications for their mechanical toughness, shear thinning behavior, and ability to support stem cell growth while preserving pluripotency. Bioprinting these hydrogels without additives enables geometry-controlled degradation and cell retrieval, providing a new approach for the encapsulation, storage, and delivery of mammalian cells.

MATERIALS TODAY COMMUNICATIONS (2022)

Review Polymer Science

A Comprehensive Assessment on the Pivotal Role of Hydrogels in Scaffold-Based Bioprinting

Matangi Parimala Chelvi Ratnamani et al.

Summary: Regenerative medicine has experienced exponential growth in the past few decades, evolving from complete tissue removal to fabricating engineered tissues using personalized living cells and customized matrices. Biofabrication through 3D printing enables precise and controlled assemblies of cells and biomaterials, mimicking the heterogenous microenvironment of living tissue. This review provides a concise framework for the bio-manufacturing process and explores the versatile applications of hydrogels in bioprinting and tissue formation.
Review Materials Science, Biomaterials

Hydrogels for 3D embedded bioprinting: a focused review on bioinks and support baths

Ke Zhou et al.

Summary: Three-dimensional (3D) bioprinting plays a crucial role in tissue engineering. The emerging solution of embedded bioprinting addresses the challenges faced in traditional bioprinting by depositing bioinks into a support bath. This review focuses on the progress of hydrogels used as bioinks and support baths.

JOURNAL OF MATERIALS CHEMISTRY B (2022)

Article Materials Science, Multidisciplinary

Investigation of rheology, printability, and biocompatibility of N,O-carboxymethyl chitosan and agarose bioinks for 3D bioprinting of neuron cells

Haley M. Butler et al.

Summary: This study found that a balanced mixture of 40% agarose and 60% NOOC is the most suitable bioink for 3D bioprinting, ensuring both cell viability and printability.

MATERIALIA (2021)

Article Biophysics

Three dimensional bioprinting technology: Applications in pharmaceutical and biomedical area

Esen Kocak et al.

Summary: 3D bioprinting is a technology that prints designed biological materials in three dimensions, with applications in producing tissues, organs, cells, and blood vessels for transplantation. It also finds uses in modeling, drug delivery systems, and drug screening. Despite limitations, this technology is of great significance in the medical field.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

Article Biochemistry & Molecular Biology

Biofabrication of skin tissue constructs using alginate, gelatin and diethylaminoethyl cellulose bioink

Lakshmi T. Somasekharan et al.

Summary: Utilizing alginate, gelatin, and diethylaminoethyl cellulose as the base, a bioink formulation for 3D bioprinting and biofabrication of skin tissue equivalents was successfully developed. The bioink proved to be printable and stable, with cell-laden 3D bioprinted constructs demonstrating excellent cell viability and biomimetic tissue histology.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Review Biochemistry & Molecular Biology

Glycosaminoglycans in Tissue Engineering: A Review

Harkanwalpreet Sodhi et al.

Summary: Glycosaminoglycans play a crucial role in tissue engineering by driving stem cell fate and promoting cell proliferation, and recent studies have explored their use in tissue constructs. The research trends in this area are evaluated, providing insights into future directions.

BIOMOLECULES (2021)

Review Chemistry, Applied

Key advances of carboxymethyl cellulose in tissue engineering & 3D bioprinting applications

Allen Zennifer et al.

Summary: This review discusses the properties of CMC and its current advances in physical and chemical modifications, as well as its potential applications in tissue engineering. Furthermore, it elaborates on the unique features of CMC in 3D bioprinting applications and highlights future prospects for broader applications in tissue engineering and 3D/4D bioprinting.

CARBOHYDRATE POLYMERS (2021)

Review Chemistry, Multidisciplinary

Recent advances in three-dimensional bioprinted nanocellulose-based hydrogel scaffolds for biomedical applications

Anam Saddique et al.

Summary: Cellulose, the most abundant biopolymer on earth, has become a promising material for biomedical applications due to its excellent physical and biological traits. Cellulose-based hydrogels, particularly those prepared using 3D bioprinting, offer customizability for complex morphology in drug delivery, tissue engineering, and scaffold applications. Despite an increasing amount of research, various issues exist that prevent the advanced applications of cellulose-based hydrogels.

KOREAN JOURNAL OF CHEMICAL ENGINEERING (2021)

Article Materials Science, Biomaterials

Biocompatibility evaluation of a 3D-bioprinted alginate-GelMA-bacteria nanocellulose (BNC) scaffold laden with oriented-growth RSC96 cells

Zongxi Wu et al.

Summary: Peripheral nerve injury can cause damage to the structure and function of peripheral nerves, and tissue engineering shows potential for regeneration but faces challenges in achieving oriented guidance. A 3D-bioprinted nerve scaffold can improve cell-oriented growth and the expression of related factors, indicating good biocompatibility and potential as a new scaffold material in neural tissue engineering.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Article Materials Science, Biomaterials

Preparation of a recombinant collagen-peptide (RHC)-conjugated chitosan thermosensitive hydrogel for wound healing

Aipeng Deng et al.

Summary: Thermoresponsive hydrogels formed by conjugating recombinant human collagen-peptide (RHC) with chitosan exhibit lower gelation temperature and superior mechanical strength, showing good biocompatibility with cells and promoting cell infiltration, vessel formation, and wound healing. Overall, the use of RHC-chitosan hydrogels is a promising and effective therapeutic approach for burn wound treatment.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Article Materials Science, Biomaterials

An immune regulatory 3D-printed alginate-pectin construct for immunoisolation of insulin producing ?-cells

Shuxian Hu et al.

Summary: New alginate-based bioinks were developed to produce cell-laden grid-shaped hydrogel constructs with stable integrity and immunomodulating capacity. Addition of pectin improved cell survival under inflammatory stress.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Review Engineering, Biomedical

Engineering bioinks for 3D bioprinting

Guy Decante et al.

Summary: Three-dimensional (3D) bioprinting technology has gained significant attention in biomedical engineering and clinical applications, with advancements in bioink development allowing for more precise mimicry of native tissue characteristics and support for biofunctionality.

BIOFABRICATION (2021)

Article Polymer Science

Three-Dimensional Printable Hydrogel Using a Hyaluronic Acid/Sodium Alginate Bio-Ink

Su Jeong Lee et al.

Summary: The study developed a method to synthesize bio-ink using HA and SA, without chemical crosslinking agents, for 3D bio-printing applications. The printed hydrogels maintained their integrity with no significant shrinkage and exhibited higher cell proliferation rates compared to SA-only bio-ink, showing promise for tissue engineering applications.

POLYMERS (2021)

Review Biotechnology & Applied Microbiology

Chitosan-Based Functional Materials for Skin Wound Repair: Mechanisms and Applications

Peipei Feng et al.

Summary: Hydrogels are effective wound dressings with unique properties, while chitosan is a polymeric biomaterial obtained by the deacetylation of chitin. Hydrogel-like functional wound dressings made from chitosan and its derivatives have received extensive attention for their effectiveness in promoting skin wound repair.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

Article Biochemistry & Molecular Biology

Silk Fibroin Enhances Cytocompatibilty and Dimensional Stability of Alginate Hydrogels for Light-Based Three-Dimensional Bioprinting

Eunu Kim et al.

Summary: The study synthesized alginate derivatives and silk fibroin to prepare bioinks, enhancing cell compatibility, and pregelated them by ionic cross-linking to increase viscosity for 3D printing. The results showed that the new bioink had improved cytocompatibility compared to traditional bioinks, making it a promising material for tissue engineering.

BIOMACROMOLECULES (2021)

Review Pharmacology & Pharmacy

Bioink: a 3D-bioprinting tool for anticancer drug discovery and cancer management

Arpita P. Tiwari et al.

Summary: Bioinks are crucial for the fabrication of artificial living-tissue constructs using 3D bioprinting technologies, with a significant application in cancer management. The ability to recreate tumor microenvironments using 3D bioprinting is a promising approach for drug development and in vitro cancer modeling.

DRUG DISCOVERY TODAY (2021)

Review Chemistry, Multidisciplinary

Chitosan as an Underrated Polymer in Modern Tissue Engineering

Marta Kolodziejska et al.

Summary: Chitosan, with its unique chemical, biological, and physical properties, is extensively used in tissue engineering as a main component in biomaterials. It can be modified and blended to meet specific requirements, making it versatile for various applications such as membranes, scaffolds, drug carriers, and hydrogels.

NANOMATERIALS (2021)

Article Biotechnology & Applied Microbiology

TEMPO-Oxidized Cellulose Nanofiber-Alginate Hydrogel as a Bioink for Human Meniscus Tissue Engineering

Xiaoyi Lan et al.

Summary: The study aimed to generate artificial menisci through 3D bioprinting technology, using cellulose nanofiber-alginate precursors and human meniscus fibrochondrocytes. The constructs produced with this combination showed characteristics more similar to the inner meniscus in terms of phenotype and gene expression.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

Review Biotechnology & Applied Microbiology

Candidate Bioinks for Extrusion 3D Bioprinting-A Systematic Review of the Literature

Sam P. Tarassoli et al.

Summary: Bioprinting is increasingly using natural biomaterials and there is no established tissue specific bioinks or bioprinting techniques. Further research and standardization of biomechanical assessment types and timing are needed.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

Review Chemistry, Physical

Recent advancements in 3D bioprinting technology of carboxymethyl cellulose-based hydrogels: Utilization in tissue engineering

Shadpour Mallakpour et al.

Summary: 3D printing technology has experienced exponential growth due to its ability to quickly print complex structures. Researchers have developed hydrogel-based inks, with CMC being a qualified candidate due to its good solubility in water and multiple carboxyl groups. Bioprinting offers high throughput and precise control of scaffolding and cells, making it valuable for tissue engineering applications.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2021)

Article Biotechnology & Applied Microbiology

3D bioprinting and microscale organization of vascularized tissue constructs using collagen-based bioink

Senthilkumar Muthusamy et al.

Summary: Bioprinting technology has made significant progress over the past decade, particularly in developing larger and more physiologic tissues. By precisely combining biological scaffold materials and cells in three-dimensional space, bioprinting has the potential to assist in locating endothelial cells in specific spatial positions to promote vessel formation in predefined areas.

BIOTECHNOLOGY AND BIOENGINEERING (2021)

Review Biochemistry & Molecular Biology

Pectin in biomedical and drug delivery applications: A review

De-qiang Li et al.

Summary: Natural macromolecules, such as pectin, are attracting attention for their biocompatibility, low toxicity, and biodegradability in biomedical and drug delivery applications. Components like rhamnogalacturonan-II in pectin play a crucial role in biomedical activities. The presence of hydroxyl and carboxyl groups in pectin contributes to its favorable properties for these applications.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Review Biochemistry & Molecular Biology

Recent trends in natural polysaccharide based bioinks for multiscale 3D printing in tissue regeneration: A review

Balaji Mahendiran et al.

Summary: Biofabrication using 3D printing technology allows for the printing of anatomically shaped native tissues, while plant-based biomaterials can mimic the characteristics of natural tissues. The focus is currently on the applications of plant-based bioinks in 3D printing.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Engineering, Biomedical

Human iPSC-derived mesodermal progenitor cells preserve their vasculogenesis potential after extrusion and form hierarchically organized blood vessels

Leyla Dogan et al.

Summary: Post-fabrication formation of proper vasculature in bioprinting remains a challenge. Human induced pluripotent stem cell-derived mesodermal progenitor cells (hiMPCs) have shown the ability to form complex vessels in vitro, and demonstrate potential in printing vascular structures in vivo.

BIOFABRICATION (2021)

Article Engineering, Biomedical

Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Produce Distinct Neural 3D In Vitro Models Depending on Alginate/Gellan Gum/Laminin Hydrogel Blend Properties

Julia Kapr et al.

Summary: The study introduces two alginate/gellan gum/laminin (ALG/GG/LAM) hydrogel blends for creating 3D neural models using human induced pluripotent stem cells (hiPSCs). The stiffness, stress relaxation of the gel blends, as well as the cell differentiation strategy, were found to influence the development of the 3D models. The embedded hiNPCs differentiated into neurons and astrocytes within the gel blends, showing potential for various applications in disease modeling and substance screenings.

ADVANCED HEALTHCARE MATERIALS (2021)

Article Polymer Science

Optimization of Polysaccharide Hydrocolloid for the Development of Bioink with High Printability/Biocompatibility for Coextrusion 3D Bioprinting

Wonseop Lim et al.

Summary: Bioink is a critical component in 3D bioprinting with characteristics that support good printability and biocompatibility. The research aimed to develop a bioink utilizing hydrocolloid materials to satisfy both printability and biocompatibility needs, and demonstrated that the mechanical properties and printability could be improved by controlling the ratio of CMC and XG in the bioink.

POLYMERS (2021)

Review Engineering, Biomedical

Natural and Synthetic Bioinks for 3D Bioprinting

Roghayeh Khoeini et al.

Summary: Bioprinting technology offers precise control over the geometric and compositional attributes of tissue constructs, using an automated approach to fabricate functional and mechanically stable structures. Bioinks, consisting of hydrogel materials and living cells, play a critical role in encapsulating appropriate cells to create functional tissue structures.

ADVANCED NANOBIOMED RESEARCH (2021)

Review Biotechnology & Applied Microbiology

Natural Biomaterials and Their Use as Bioinks for Printing Tissues

Claire Benwood et al.

Summary: Extrusion bioprinting, the most common form of bioprinting, can create personalized tissues for drug testing and cancer research using various materials. This paper reviews the properties and functions of natural bioinks in hard and soft tissue engineering, highlighting the importance of multi-component bioinks and potential future research directions.

BIOENGINEERING-BASEL (2021)

Review Pharmacology & Pharmacy

Cellulose Bio-ink on 3D Printing Applications

Ramesh Ganpisetti et al.

Summary: Nanocellulose polymers, particularly CNF and CNC, have played a crucial role in biomedical applications and have facilitated advancements in skin grafting, organ transplants, and cancer screening and treatment. This paper explores the use of various cellulose polymers in these applications, highlighting advancements in modification for enhanced effectiveness in the medical field. Additionally, it reviews the journey of 3D bio-ink printing of cellulose polymers and its influence on the application of 4D bioprinting.

JOURNAL OF YOUNG PHARMACISTS (2021)

Article Engineering, Biomedical

Bioprinting and In Vitro Characterization of an Eggwhite-Based Cell-Laden Patch for Endothelialized Tissue Engineering Applications

Yasaman Delkash et al.

Summary: This study developed a novel bioink by combining chicken eggwhite and sodium alginate for 3D bioprinting, resulting in patches with good mechanical properties and cell bioactivity.

JOURNAL OF FUNCTIONAL BIOMATERIALS (2021)

Review Nanoscience & Nanotechnology

Review of Bioprinting in Regenerative Medicine: Naturally Derived Bioinks and Stem Cells

Abolfazl Salehi Moghaddam et al.

Summary: Regenerative medicine utilizes bioprinting techniques to create active tissues for transplantation, offering the potential to repair or substitute defective tissues. 3D bioprinting of stem cells allows for the recreation of tissues, organs, and microenvironments, showcasing promising results in tissue regeneration.

ACS APPLIED BIO MATERIALS (2021)

Article Engineering, Biomedical

Bioinks for 3D Bioprinting: A Scientometric Analysis of Two Decades of Progress

Sara Cristina Pedroza-Gonzalez et al.

Summary: This scientometric analysis examines the development and use of bioinks for 3D bioprinting in the period from January 2000 to June 2019. The main considerations for bioink applications include cost, availability, practicality, and basic biological factors. Extrusion bioprinting is currently the most popular technique, with bioinks commonly used for generic characterization and cartilage bioprinting applications. Despite advancements in functional bioinks, the field is still in early stages with alginate and gelatin methacryloyl being the most commonly used hydrogels.

INTERNATIONAL JOURNAL OF BIOPRINTING (2021)

Article Nanoscience & Nanotechnology

Cell-Laden Nanocellulose/Chitosan-Based Bioinks for 3D Bioprinting and Enhanced Osteogenic Cell Differentiation

Panita Maturavongsadit et al.

Summary: 3D bioprinting using nanocellulose/chitosan-based bioink shows promising potential for bone tissue engineering and regeneration. By optimizing bioink formulations, fast gelation kinetics and shape integrity of constructs post 3D bioprinting can be achieved. The incorporation of CNCs and pre-osteoblast cells enhances the rheological and mechanical properties of the bioinks, as well as promotes osteogenesis in chitosan scaffolds.

ACS APPLIED BIO MATERIALS (2021)

Article Chemistry, Multidisciplinary

Fabrication and characterization of 3D-printed gellan gum/starch composite scaffold for Schwann cells growth

Liling Zhang et al.

Summary: In this study, new three-dimensional gellan gum/starch scaffolds were prepared by 3D printing technology to promote Schwann cells growth for peripheral nerve regeneration. The scaffolds exhibited good physiochemical properties and biocompatibility, indicating a potential application in nerve regeneration.

NANOTECHNOLOGY REVIEWS (2021)

Article Engineering, Biomedical

Human platelet lysate-based nanocomposite bioink for bioprinting hierarchical fibrillar structures

Barbara B. Mendes et al.

BIOFABRICATION (2020)

Article Chemistry, Applied

Applications of chitin and chitosan nanofibers in bone regenerative engineering

Fenghua Tao et al.

CARBOHYDRATE POLYMERS (2020)

Review Materials Science, Multidisciplinary

Hydrogel-based 3D bioprinting: A comprehensive review on cell-laden hydrogels, bioink formulations, and future perspectives

Janitha M. Unagolla et al.

APPLIED MATERIALS TODAY (2020)

Article Nanoscience & Nanotechnology

Nanoengineered Osteoinductive Bioink for 3D Bioprinting Bone Tissue

David Chimene et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Review Engineering, Biomedical

Progress in 3D bioprinting technology for tissue/organ regenerative engineering

Ishita Matai et al.

BIOMATERIALS (2020)

Review Chemistry, Applied

Dynamic plant-derived polysaccharide-based hydrogels

Pejman Heidarian et al.

CARBOHYDRATE POLYMERS (2020)

Review Chemistry, Multidisciplinary

Drug delivery applications of chitin and chitosan: a review

Rabinarayan Parhi

ENVIRONMENTAL CHEMISTRY LETTERS (2020)

Article Biochemistry & Molecular Biology

Engineering gelatin-based alginate/carbon nanotubes blend bioink for direct 3D printing of vessel constructs

Liying Li et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Chemistry, Multidisciplinary

Inorganic Sol-Gel Polymerization for Hydrogel Bioprinting

Titouan Montheil et al.

ACS OMEGA (2020)

Article Chemistry, Applied

DLP printing photocurable chitosan to build bio-constructs for tissue engineering

Yi Shen et al.

CARBOHYDRATE POLYMERS (2020)

Article Engineering, Biomedical

Preliminary investigation on a new natural based poly(gamma-glutamic acid)/Chitosan bioink

Silvia Pisani et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2020)

Article Polymer Science

A universal self-eroding sacrificial bioink that enables bioprinting at room temperature

Levent Aydin et al.

POLYMERS FOR ADVANCED TECHNOLOGIES (2020)

Review Engineering, Biomedical

Advances in Extrusion 3D Bioprinting: A Focus on Multicomponent Hydrogel-Based Bioinks

Xiaolin Cui et al.

ADVANCED HEALTHCARE MATERIALS (2020)

Article Engineering, Biomedical

Designing vascular supportive albumen-rich composite bioink for organ 3D printing

Suihong Liu et al.

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2020)

Article Chemistry, Multidisciplinary

Polysaccharide-Based Bioink Formulation for 3D Bioprinting of an In Vitro Model of the Human Dermis

Tanja Zidaric et al.

NANOMATERIALS (2020)

Article Chemistry, Multidisciplinary

Cell-Laden Thermosensitive Chitosan Hydrogel Bioinks for 3D Bioprinting Applications

Jongbeom Ku et al.

APPLIED SCIENCES-BASEL (2020)

Article Nanoscience & Nanotechnology

Peptide Chitosan/Dextran Core/Shell Vascularized 3D Constructs for Wound Healing

Paul R. Turner et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Review Education, Scientific Disciplines

Biomaterials in 3D Printing: A Special Emphasis on Nanocellulose

Ravindra Vijay Badhe et al.

INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH (2020)

Article Chemistry, Multidisciplinary

Design and Synthesis of Chitosan-Gelatin Hybrid Hydrogels for 3D Printablein vitroModels

Sofia Magli et al.

FRONTIERS IN CHEMISTRY (2020)

Article Food Science & Technology

Microbial exopolysaccharides for immune enhancement: Fermentation, modifications and bioactivities

Worraprat Chaisuwan et al.

FOOD BIOSCIENCE (2020)

Review Biotechnology & Applied Microbiology

Hydrogels for Bioprinting: A Systematic Review of Hydrogels Synthesis, Bioprinting Parameters, and Bioprinted Structures Behavior

Enrique Mancha Sanchez et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Article Chemistry, Physical

3D Bioprinted Highly Elastic Hybrid Constructs for Advanced Fibrocartilaginous Tissue Regeneration

Joao B. Costa et al.

CHEMISTRY OF MATERIALS (2020)

Article Polymer Science

Light Processable Starch Hydrogels

Camilla Noe et al.

POLYMERS (2020)

Review Chemistry, Physical

Recent Trends in Three-Dimensional Bioinks Based on Alginate for Biomedical Applications

Farnoosh Pahlevanzadeh et al.

MATERIALS (2020)

Article Polymer Science

3D Printing of a Reactive Hydrogel Bio-Ink Using a Static Mixing Tool

Maria Puertas-Bartolome et al.

POLYMERS (2020)

Article Engineering, Biomedical

Hybrid Printing Using Cellulose Nanocrystals Reinforced GelMA/HAMA Hydrogels for Improved Structural Integration

Yuchao Fan et al.

ADVANCED HEALTHCARE MATERIALS (2020)

Review Materials Science, Biomaterials

Multicomponent polysaccharide alginate-based bioinks

Carmen C. Piras et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Review Engineering, Biomedical

Hyaluronic acid as a bioink for extrusion-based 3D printing

D. Petta et al.

BIOFABRICATION (2020)

Article Engineering, Biomedical

3D bioprinted hyaluronic acid-based cell-laden scaffold for brain microenvironment simulation

Liang Ma et al.

BIO-DESIGN AND MANUFACTURING (2020)

Article Engineering, Biomedical

3D bioprinted breast tumor model for structure-activity relationship study

Xiaorui Li et al.

BIO-DESIGN AND MANUFACTURING (2020)

Article Thermodynamics

THERMOKINETICS AND RHEOLOGY OF AGAROSE GEL APPLIED TO BIOPRINTING TECHNOLOGY

Boris Pokusaev et al.

THERMAL SCIENCE (2020)

Article Engineering, Biomedical

Extrusion-Based Bioprinting through Glucose-Mediated Enzymatic Hydrogelation

Enkhtuul Gantumur et al.

INTERNATIONAL JOURNAL OF BIOPRINTING (2020)

Review Chemistry, Applied

Thermoresponsive polysaccharides and their thermoreversible physical hydrogel networks

Sarah Graham et al.

CARBOHYDRATE POLYMERS (2019)

Article Chemistry, Physical

Engineering nanocellulose hydrogels for biomedical applications

Rodrigo Curvello et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2019)

Article Biochemistry & Molecular Biology

Hydrogels based on ozonated cassava starch: Effect of ozone processing and gelatinization conditions on enhancing 3D-printing applications

Bianca C. Maniglia et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Review Engineering, Biomedical

Review of alginate-based hydrogel bioprinting for application in tissue engineering

Prasansha Rastogi et al.

BIOFABRICATION (2019)

Article Chemistry, Multidisciplinary

Fabrication of Complex Hydrogel Structures Using Suspended Layer Additive Manufacturing (SLAM)

Jessica J. Senior et al.

ADVANCED FUNCTIONAL MATERIALS (2019)

Article Biochemistry & Molecular Biology

Extrusion-based 3D printing of photo-crosslinkable gelatin and κ-carrageenan hydrogel blends for adipose tissue regeneration

Liesbeth Tytgat et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Engineering, Biomedical

Enhanced rheological behaviors of alginate hydrogels with carrageenan for extrusion-based bioprinting

Myoung Hwan Kim et al.

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2019)

Article Multidisciplinary Sciences

Immobilization of planktonic algal spores by inkjet printing

Hwa-Rim Lee et al.

SCIENTIFIC REPORTS (2019)

Article Multidisciplinary Sciences

Study of 3D-printed chitosan scaffold features after different post-printing gelation processes

Carlo Bergonzi et al.

SCIENTIFIC REPORTS (2019)

Article Materials Science, Multidisciplinary

Polysaccharide hydrogels for multiscale 3D printing of pullulan scaffolds

Gioia Della Giustina et al.

MATERIALS & DESIGN (2019)

Article Engineering, Biomedical

Printing bone in a gel: using nanocomposite bioink to print functionalised bone scaffolds

G. Cidonio et al.

MATERIALS TODAY BIO (2019)

Review Engineering, Mechanical

Plant-Derived Biomaterials: A Review of 3D Bioprinting and Biomedical Applications

Thomas H. Jovic et al.

FRONTIERS IN MECHANICAL ENGINEERING-SWITZERLAND (2019)

Review Engineering, Biomedical

3D bioprinting and its in vivo applications

Nhayoung Hong et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2018)

Article Nanoscience & Nanotechnology

Three-Dimensional Bioprinting of Oppositely Charged Hydrogels with Super Strong Interface Bonding

Huijun Li et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Article Nanoscience & Nanotechnology

Nanoengineered Ionic-Covalent Entanglement (NICE) Bioinks for 3D Bioprinting

David Chimene et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Review Pharmacology & Pharmacy

3D bioprinting of tissues and organs for regenerative medicine

Sanjairaj Vijayavenkataraman et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

Review Chemistry, Applied

Agarose-based biomaterials for tissue engineering

Payam Zarrintaj et al.

CARBOHYDRATE POLYMERS (2018)

Review Chemistry, Applied

Carrageenan based hydrogels for drug delivery, tissue engineering and wound healing

Ramanathan Yegappan et al.

CARBOHYDRATE POLYMERS (2018)

Review Chemistry, Applied

Application of xanthan gum as polysaccharide in tissue engineering: A review

Anuj Kumar et al.

CARBOHYDRATE POLYMERS (2018)

Review Materials Science, Paper & Wood

3D printing with cellulose materials

Qianqian Wang et al.

CELLULOSE (2018)

Review Biochemical Research Methods

The road to animal-free glycosaminoglycan production: current efforts and bottlenecks

Abinaya Badri et al.

CURRENT OPINION IN BIOTECHNOLOGY (2018)

Review Biochemistry & Molecular Biology

Bioprinting and its applications in tissue engineering and regenerative medicine

Waeljumah Aljohani et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Materials Science, Multidisciplinary

3D bioprinting of cell-laden scaffolds for intervertebral disc regeneration

Duo Hu et al.

MATERIALS LETTERS (2018)

Article Materials Science, Biomaterials

Collagen-alginate as bioink for three-dimensional (3D) cell printing based cartilage tissue engineering

Xingchen Yang et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2018)

Review Biotechnology & Applied Microbiology

Discovering Cell-Adhesion Peptides in Tissue Engineering: Beyond RGD

Nick Huettner et al.

TRENDS IN BIOTECHNOLOGY (2018)

Article Chemistry, Physical

3D Printability of Alginate-Carboxymethyl Cellulose Hydrogel

Ahasan Habib et al.

MATERIALS (2018)

Review Polymer Science

Review of Recent Development on Preparation, Properties, and Applications of Cellulose-Based Functional Materials

Ya-Yu Li et al.

INTERNATIONAL JOURNAL OF POLYMER SCIENCE (2018)

Article Materials Science, Multidisciplinary

3D printing of concentrated alginate/gelatin scaffolds with homogeneous nano apatite coating for bone tissue engineering

Yongxiang Luo et al.

MATERIALS & DESIGN (2018)

Review Medicine, Research & Experimental

A review of natural polysaccharides for drug delivery applications: Special focus on cellulose, starch and glycogen

V. Gopinath et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Chemistry, Applied

Nanosilicate embedded agarose hydrogels with improved bioactivity

Fuat Topuz et al.

CARBOHYDRATE POLYMERS (2018)

Article Biochemistry & Molecular Biology

Composite Biomaterials as Long-Lasting Scaffolds for 3D Bioprinting of Highly Aligned Muscle Tissue

Andrea Garcia-Lizarribar et al.

MACROMOLECULAR BIOSCIENCE (2018)

Review Polymer Science

Hydrogel Biomaterials for Stem Cell Microencapsulation

Goeun Choe et al.

POLYMERS (2018)

Article Chemistry, Multidisciplinary

A single-component hydrogel bioink for bioprinting of bioengineered 3D constructs for dermal tissue engineering

Ruben F. Pereira et al.

MATERIALS HORIZONS (2018)

Article Materials Science, Biomaterials

Agarose-Based Hydrogels as Suitable Bioprinting Materials for Tissue Engineering

Gabriel R. Lopez-Marcial et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2018)

Review Biochemistry & Molecular Biology

Chitosan-Based Nanomaterials for Drug Delivery

Jianghua Li et al.

MOLECULES (2018)

Review Chemistry, Multidisciplinary

Hydrogels as intelligent materials: A brief review of synthesis, properties and applications

Mostafa Mahinroosta et al.

MATERIALS TODAY CHEMISTRY (2018)

Review Polymer Science

Cellulose modification and shaping - a review

Kerstin Jedvert et al.

JOURNAL OF POLYMER ENGINEERING (2017)

Review Materials Science, Biomaterials

Naturally derived proteins and glycosaminoglycan scaffolds for tissue engineering applications

Nehar Celikkin et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

Review Materials Science, Biomaterials

Nanocellulosic materials as bioinks for 3D bioprinting

Carmen C. Piras et al.

BIOMATERIALS SCIENCE (2017)

Article Nanoscience & Nanotechnology

Shear-Thinning and Thermo-Reversible Nanoengineered Inks for 3D Bioprinting

Scott A. Wilson et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Review Engineering, Biomedical

Polysaccharide matrices used in 3D in vitro cell culture systems

Dorina Diekjurgen et al.

BIOMATERIALS (2017)

Article Engineering, Biomedical

Roles of support materials in 3D bioprinting - Present and future

Ratima Suntornnond et al.

INTERNATIONAL JOURNAL OF BIOPRINTING (2017)

Review Engineering, Biomedical

3D printing of nano-cellulosic biomaterials for medical applications

Sahar Sultan et al.

CURRENT OPINION IN BIOMEDICAL ENGINEERING (2017)

Review Engineering, Biomedical

Bioprinting for vascular and vascularized tissue biofabrication

Pallab Datta et al.

ACTA BIOMATERIALIA (2017)

Review Biotechnology & Applied Microbiology

The bioink: A comprehensive review on bioprintable materials

Monika Hospodiuk et al.

BIOTECHNOLOGY ADVANCES (2017)

Review Pharmacology & Pharmacy

Application areas of 3D bioprinting

Ibrahim T. Ozbolat et al.

DRUG DISCOVERY TODAY (2016)

Review Materials Science, Biomaterials

Tissue engineering with gellan gum

L. R. Stevens et al.

BIOMATERIALS SCIENCE (2016)

Review Biotechnology & Applied Microbiology

Biotechnological production of hyaluronic acid: a mini review

Jun Hui Sze et al.

3 BIOTECH (2016)

Review Biotechnology & Applied Microbiology

Biotechnological production of hyaluronic acid: a mini review

Jun Hui Sze et al.

3 BIOTECH (2016)

Review Biochemistry & Molecular Biology

Applications of Alginate-Based Bioinks in 3D Bioprinting

Eneko Axpe et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Review Engineering, Biomedical

Bioink properties before, during and after 3D bioprinting

Katja Hoelzl et al.

BIOFABRICATION (2016)

Article Engineering, Biomedical

3D printing of layered brain-like structures using peptide modified gellan gum substrates

Rodrigo Lozano et al.

BIOMATERIALS (2015)

Article Biochemical Research Methods

Bioprinting of 3D hydrogels

M. M. Stanton et al.

LAB ON A CHIP (2015)

Review Biotechnology & Applied Microbiology

Crosslinking biopolymers for biomedical applications

Narendra Reddy et al.

TRENDS IN BIOTECHNOLOGY (2015)

Article Engineering, Biomedical

Biomaterials for Integration with 3-D Bioprinting

Aleksander Skardal et al.

ANNALS OF BIOMEDICAL ENGINEERING (2015)

Article Engineering, Biomedical

Biofabrication of tissue constructs by 3D bioprinting of cell-laden microcarriers

Riccardo Levato et al.

BIOFABRICATION (2014)

Article Materials Science, Biomaterials

Protein-based materials: from sources to innovative sustainable materials for biomedical applications

Nuno H. C. S. Silva et al.

JOURNAL OF MATERIALS CHEMISTRY B (2014)

Article Engineering, Biomedical

Photocrosslinkable Kappa-Carrageenan Hydrogels for Tissue Engineering Applications

Silvia M. Mihaila et al.

ADVANCED HEALTHCARE MATERIALS (2013)

Review Food Science & Technology

Food Gels: Gelling Process and New Applications

Soumya Banerjee et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2012)

Review Biochemistry & Molecular Biology

Advances in biomedical applications of pectin gels

F. Munarin et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2012)

Review Chemistry, Multidisciplinary

Nanocelluloses: A New Family of Nature-Based Materials

Dieter Klemm et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Review Biotechnology & Applied Microbiology

Pullulan: biosynthesis, production, and applications

Kuan-Chen Cheng et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2011)

Article Engineering, Biomedical

Scaffold-free vascular tissue engineering using bioprinting

Cyrille Norotte et al.

BIOMATERIALS (2009)

Review Chemistry, Applied

Carrageenans: Biological properties, chemical modifications and structural analysis - A review

Vanessa Leiria Campo et al.

CARBOHYDRATE POLYMERS (2009)

Article Microbiology

Role of Intracellular Polysaccharide in Persistence of Streptococcus mutans

Monica Busuioc et al.

JOURNAL OF BACTERIOLOGY (2009)

Review Chemistry, Applied

Pullulan: Microbial sources, production and applications

Ram S. Singh et al.

CARBOHYDRATE POLYMERS (2008)

Review Polymer Science

Chitin and chitosan: Properties and applications

Marguerite Rinaudo

PROGRESS IN POLYMER SCIENCE (2006)

Article Food Science & Technology

Pectin: new insights into an old polymer are starting to gel

WGT Willats et al.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2006)

Review Biotechnology & Applied Microbiology

Leuconostoc dextransucrase and dextran:: production, properties and applications

M Naessens et al.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY (2005)

Review Chemistry, Multidisciplinary

Cellulose: Fascinating biopolymer and sustainable raw material

D Klemm et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)

Review Food Science & Technology

Starch - composition, fine structure and architecture

RF Tester et al.

JOURNAL OF CEREAL SCIENCE (2004)

Review Biotechnology & Applied Microbiology

Xanthan gum:: production, recovery, and properties

F García-Ochoa et al.

BIOTECHNOLOGY ADVANCES (2000)