Antioxidative, Anti-Inflammatory, Anti-Obesogenic, and Antidiabetic Properties of Tea Polyphenols-The Positive Impact of Regular Tea Consumption as an Element of Prophylaxis and Pharmacotherapy Support in Endometrial Cancer

Endometrial cancer (EC) is second only to cervical carcinoma among the most commonly diagnosed malignant tumours of the female reproductive system. The available literature provides evidence for the involvement of 32 genes in the hereditary incidence of EC. The physiological markers of EC and coexisting diet-dependent maladies include antioxidative system disorders but also progressing inflammation; hence, the main forms of prophylaxis and pharmacotherapy ought to include a diet rich in substances aiding the organism's response to this type of disorder, with a particular focus on ones suitable for lifelong consumption. Tea polyphenols satisfy those requirements due to their proven antioxidative, anti-inflammatory, anti-obesogenic, and antidiabetic properties. Practitioners ought to consider promoting tea consumption among individuals genetically predisposed for EC, particularly given its low cost, accessibility, confirmed health benefits, and above all, suitability for long-term consumption regardless of the patient's age. The aim of this paper is to analyse the potential usability of tea as an element of prophylaxis and pharmacotherapy support in EC patients. The analysis is based on information available from worldwide literature published in the last 15 years.

Automated summary

Endometrial cancer (EC) is a commonly diagnosed malignant tumor in the female reproductive system. Literature suggests that 32 genes are involved in the hereditary incidence of EC. The physiological markers of EC include disorders in the antioxidative system and inflammation. A diet rich in substances aiding the response to this disorder, particularly those suitable for lifelong consumption, is important for prophylaxis and pharmacotherapy. Tea polyphenols have proven antioxidative, anti-inflammatory, anti-obesogenic, and antidiabetic properties, making tea consumption beneficial for individuals genetically predisposed for EC.