Reduction in the infection fatality rate of Omicron variant compared with previous variants in South Africa

Editorial Material Public, Environmental & Occupational Health

Highly mutated SARS-CoV-2 Omicron variant sparks significant concern among global experts - What is known so far?

Sujan Poudel et al.

TRAVEL MEDICINE AND INFECTIOUS DISEASE (2022)

Article Environmental Sciences

Multiple COVID-19 Waves and Vaccination Effectiveness in the United States

Lixin Lin et al.

Summary: This study finds that the vaccination campaign in the US has significantly reduced the COVID-19 mortality rate and prevented a large number of deaths, as shown through modeling.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

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Article Infectious Diseases

Decreased severity of disease during the first global omicron variant covid-19 outbreak in a large hospital in tshwane, south africa

F. Abdullah et al.

Summary: This study analyzed the clinical data of COVID-19 patients admitted to a hospital in Tshwane during the Omicron wave, and found that the severity of the disease was decreased compared to previous waves, with lower death rates and ICU admissions.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2022)

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Article Mathematical & Computational Biology

Two waves of COIVD-19 in Brazilian cities and vaccination impact

Lixin Lin et al.

Summary: This study modifies the SEIR model to evaluate the effects of COVID-19 vaccination in Brazil using death data from 20 cities. The findings suggest that the vaccination effects vary across cities and reinfection is not crucial in the second wave. The relatively high infection fatality rate may be attributed to the breakdown of the healthcare system.

MATHEMATICAL BIOSCIENCES AND ENGINEERING (2022)

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Article Multidisciplinary Sciences

Detection of a SARS-CoV-2 variant of concern in South Africa

Houriiyah Tegally et al.

Summary: The article describes a newly emerged lineage of SARS-CoV-2, 501Y.V2, characterized by eight mutations in the spike protein, which may result in increased transmissibility or immune escape. This lineage originated in South Africa and quickly became dominant in Eastern Cape, Western Cape, and KwaZuluNatal provinces within weeks.

NATURE (2021)

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Article Psychology, Biological

A global database of COVID-19 vaccinations

Edouard Mathieu et al.

Summary: An effective rollout of COVID-19 vaccines is crucial in ending the pandemic, and Our World in Data's vaccination dataset tracks the progress and scale of vaccine distribution globally, aiding policymakers and researchers in understanding the global vaccination efforts.

NATURE HUMAN BEHAVIOUR (2021)

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Article Public, Environmental & Occupational Health

Using Proper Mean Generation Intervals in Modeling of COVID-19

Xiujuan Tang et al.

Summary: In SEIR epidemic models, the mean generation interval (GI) for COVID-19 is reported to be as short as 5 days, but discrepancies in parameter values lead to different results. Using suitable epidemiological parameter values is crucial for proper estimation and prediction. Assessment of COVID-19 transmission dynamics in Belgium, Israel, and the UAE revealed that Belgium has the highest infection attack rate.

FRONTIERS IN PUBLIC HEALTH (2021)

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Letter Biochemistry & Molecular Biology

SARS-CoV-2 Omicron strain exhibits potent capabilities for immune evasion and viral entrance

Xiantao Zhang et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

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Article Medicine, Research & Experimental

SARS-CoV-2 Omicron variant: Characteristics and prevention

Xuemei He et al.

Summary: The new SARS-CoV-2 variant B.1.1.529 named Omicron, reported in South Africa, has raised global concerns after being designated as a variant of concern by the WHO. With a high number of mutations, including 15 in the spike receptor-binding domain, the Omicron variant shares similarities with previous VOCs, sparking worries about its transmissibility and immune evasion.

MEDCOMM (2021)

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Article Health Care Sciences & Services