Journal
INFLAMMATORY BOWEL DISEASES
Volume 29, Issue 2, Pages 324-327Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/ibd/izac128
Keywords
ulcerative colitis; clinical trials; remission; outcome sensitivity; treatment efficacy
Categories
Ask authors/readers for more resources
This systematic review and quantitative analysis of placebo-controlled ulcerative colitis induction trials showed higher histologic remission rates compared to clinical and endoscopic remission rates at the same timepoint, and there were no significant differences in relative risks for these outcomes between treatment groups. This supports the concept that histologic remission is as sensitive as clinical or endoscopic remission.
Lay Summary This systemic review and quantitative analysis of placebo-controlled ulcerative colitis (UC) induction trials found higher pooled histologic remission rates compared with clinical and endoscopic remission rates at the same timepoint, and no significant differences in pooled relative risks for these outcomes between treatment groups; supporting the concept that histologic remission is not less sensitive than clinical or endoscopic remission.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available