4.5 Article

Bayesian Variable Selection on Model Spaces Constrained by Heredity Conditions

Journal

JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS
Volume 25, Issue 2, Pages 515-535

Publisher

AMER STATISTICAL ASSOC
DOI: 10.1080/10618600.2015.1056793

Keywords

Intrinsic prior; Markov chain Monte Carlo; Model priors; Multiple testing; Multiplicity penalization; Strong heredity; Weak heredity; Well-formulated models

Funding

  1. National Science Foundation [DMS-1105127, DMS-1127914]
  2. National Institutes of Health [U01GM070749, U54GM111274]

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This article investigates Bayesian variable selection when there is a hierarchical dependence structure on the inclusion of predictors in the model. In particular, we study the type of dependence found in polynomial response surfaces of orders two and higher, whose model spaces are required to satisfy weak or strong heredity conditions. These conditions restrict the inclusion of higher-order terms depending upon the inclusion of lower-order parent terms. We develop classes of priors on the model space, investigate their theoretical and finite sample properties, and provide a Metropolis Hastings algorithm for searching the space of models. The tools proposed allow fast and thorough exploration of model spaces that account for hierarchical polynomial structure in the predictors and provide control of the inclusion of false positives in high posterior probability models.

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