4.4 Article

1,3,5,8-Tetrahydroxyxanthone suppressed adipogenesis via activating Hedgehog signaling in 3T3-L1 adipocytes

Related references

Note: Only part of the references are listed.
Review Genetics & Heredity

The genetics of obesity: from discovery to biology

Ruth J. F. Loos et al.

Summary: In this review, Loos and Yeo summarize our current understanding of the genetic underpinnings of monogenic and polygenic obesity, highlighting shared genetic and biological underpinnings between the two forms of obesity. Genome-wide association studies with increasing sample sizes have driven recent discoveries, with post-GWAS collaborations facilitating translation of genetic loci into meaningful biology and new treatment avenues.

NATURE REVIEWS GENETICS (2022)

Article Endocrinology & Metabolism

Gli1 Defines a Subset of Fibro-adipogenic Progenitors that Promote Skeletal Muscle Regeneration With Less Fat Accumulation

Lutian Yao et al.

Summary: Gli1+ FAPs play a crucial role in skeletal muscle repair by relying on Hh signaling to promote the growth of regenerating myofibers. These cells demonstrate superior clonogenicity and reduced adipogenic differentiation ability, enhancing myogenesis and reducing adipogenesis after injury.

JOURNAL OF BONE AND MINERAL RESEARCH (2021)

Article Plant Sciences

Caudatin suppresses adipogenesis in 3T3-L1 adipocytes and reduces body weight gain in high-fat diet-fed mice through activation of hedgehog signaling

Shuai Qiu et al.

Summary: The study demonstrated that the C-21 steroid caudatin inhibits adipogenesis and obesity by activating the Hh signaling pathway, reducing lipid accumulation and body weight gain.

PHYTOMEDICINE (2021)

Article Food Science & Technology

Anti-obesity activity of Heracleum moellendorffii root extracts in 3T3-L1 adipocytes

Na Gyeong Geum et al.

Summary: HMR inhibited lipid accumulation in 3T3-L1 cells by suppressing the expression of proteins related to lipid accumulation and inducing proteasomal degradation of CEBP alpha via JNK and GSK3 beta activation.

FOOD SCIENCE & NUTRITION (2021)

Article Endocrinology & Metabolism

Harnessing adipogenesis to prevent obesity

Nida Haider et al.

ADIPOCYTE (2019)

Article Food Science & Technology

Anti-adipogenic Effect of β-Carboline Alkaloids from Garlic (Allium sativum)

Su Cheol Baek et al.

FOODS (2019)

Article Agriculture, Multidisciplinary

Sulforaphene Inhibition of Adipogenesis via Hedgehog Signaling in 3T3-L1 Adipocytes

Jing Chen et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)

Review Medicine, Research & Experimental

The role of the Hedgehog signaling pathway in cancer: A comprehensive review

Ana Marija Skoda et al.

BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES (2018)

Article Biochemistry & Molecular Biology

Bioactive Constituents from the Whole Plants of Gentianella acuta (Michx.) Hulten

Zhijuan Ding et al.

MOLECULES (2017)

Article Cell Biology

Cilia and Obesity

Christian Vaisse et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)

Article Agriculture, Multidisciplinary

α-Mangostin Regulates Hepatic Steatosis and Obesity through SirT1-AMPK and PPARγ Pathways in High-Fat Diet-Induced Obese Mice

Young Hee Choi et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2015)

Article Chemistry, Medicinal

Xanthones from Swertia mussotii as Multitarget-Directed Antidiabetic Agents

Huan-Huan Zheng et al.

CHEMMEDCHEM (2014)

Article Biochemistry & Molecular Biology

Peroxisome Proliferator-Activated Receptor γ and C/EBPα Synergistically Activate Key Metabolic Adipocyte Genes by Assisted Loading

Maria Stahl Madsen et al.

MOLECULAR AND CELLULAR BIOLOGY (2014)

Article Cell Biology

Adipocyte and adipogenesis

Aus Tariq Ali et al.

EUROPEAN JOURNAL OF CELL BIOLOGY (2013)

Review Cell Biology

The mechanisms of Hedgehog signalling and its roles in development and disease

James Briscoe et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Article Pharmacology & Pharmacy

1,3,5,8-Tetrahydroxyxanthone regulates ANGPTL3-LPL pathway to lessen the ketosis in mice

Hong-Bo Xiao et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2012)

Review Endocrinology & Metabolism

New developments in adipogenesis

Martina I. Lefterova et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)

Article Biochemistry & Molecular Biology

Disruption of intraflagellar in adult mice leads to transport obesity and slow-onset cystic kidney disease

James R. Davenport et al.

CURRENT BIOLOGY (2007)

Review Multidisciplinary Sciences

Adipocytes as regulators of energy balance and glucose homeostasis

Evan D. Rosen et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Sequential gene promoter interactions by C/EBPβ, C/EBPα, and PPARγ during adipogenesis

QQ Tang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Medicine, General & Internal

Obesity and the risk of heart failure

S Kenchaiah et al.

NEW ENGLAND JOURNAL OF MEDICINE (2002)

Article Cell Biology

C/EBP alpha induces adipogenesis through PPAR gamma: a unified pathway

ED Rosen et al.

GENES & DEVELOPMENT (2002)

Article Multidisciplinary Sciences

C/EBPα is required for differentiation of white, but not brown, adipose tissue

HG Linhart et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Medicine, General & Internal

Impact of overweight on the risk of developing common chronic diseases during a 10-year period

AE Field et al.

ARCHIVES OF INTERNAL MEDICINE (2001)