4.7 Article

The effective components of herbal medicines used for prevention and control of fish diseases

Journal

FISH & SHELLFISH IMMUNOLOGY
Volume 126, Issue -, Pages 73-83

Publisher

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fsi.2022.05.036

Keywords

Herbal medicine; Immunostimulant; Antioxidation; Anti-pathogenic activity; Prevention and control of fish diseases

Funding

  1. National Natural Science Foundation of China [31802333]
  2. China Agricultural Research System of MOF and MARA [CARS-47]
  3. Fujian Science and Technology Department [2021N5008]
  4. Institute of Oceanology of Fuzhou [2021F02]

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The increasing demand for fish consumption has led to the rapid growth of fish aquaculture. However, the use of antibiotics and chemicals for disease prevention and control in fish farming is restricted due to issues such as drug residues, pathogen resistance, and environmental pollution. Herbs and their extracts have emerged as promising alternatives because they are effective, safe, environmentally friendly, and have lower drug resistance. This paper comprehensively summarizes the research progress of herbal ingredients used for disease prevention and control in fish, particularly focusing on their mechanisms of action, and highlights the potential application of herbal medicines in fish aquaculture.
The increasing demand for fish consumption has promoted the rapid development of fish aquaculture. With the continuous expansion of culture scale and the deterioration of culture environment, various diseases have broken out frequently, leading to huge economic losses to fish farming. Antibiotics and chemicals are common options to prevent and control of fish diseases, but their use is now restricted or even banned due to serious problems such as drug residues, pathogen resistance, and environmental pollution. Herbs and their extracts have increasingly become promising supplements and alternatives, because of their effectiveness, safety, environmental friendliness and less drug resistance. The application of herbal medicines in prevention and control of fish diseases is mainly attributed to the powerful immune enhancement, antioxidation or direct anti-pathogenic efficacies of their effective components, including mainly polyphenols, polysaccharides, saponins, flavonoids, alkaloids, and essential oils. Recently these herbal active ingredients have been extensively studied for their efficacies in prevention and control of viral, bacterial, parasitic, and fungal diseases in fish. In the present paper, we comprehensively summarize the research progress of the active ingredients of herbal medicines used for prevention and control of fish diseases, especially of their action mechanisms, and highlight the potential application of the herbal medicines in fish aquaculture.

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