4.5 Article

MHC class II genotype-by-pathogen genotype interaction for infection prevalence in a natural rodent-Borrelia system

Related references

Note: Only part of the references are listed.
Article Ecology

Contemporary selection on MHC genes in a free-living ruminant population

Wei Huang et al.

Summary: This study examines the role of MHC variation in fitness measurements of wild Soay sheep. The results show that MHC genes are associated with lifetime breeding success, juvenile survival, and adult fitness components. The study also suggests that the mode of selection on specific fitness components may differ from selection on total fitness.

ECOLOGY LETTERS (2022)

Review Ecology

Coevolutionary theory of hosts and parasites

Lydia J. Buckingham et al.

Summary: This review examines the role of theoretical models in understanding host-parasite coevolution and discusses the important features and results of these models. It also discusses the recent trends in the field and suggests future research directions.

JOURNAL OF EVOLUTIONARY BIOLOGY (2022)

Article Multidisciplinary Sciences

Malaria protection due to sickle haemoglobin depends on parasite genotype

Gavin Band et al.

Summary: This study found a strong association between host sickle haemoglobin (HbS) and three regions of the parasite genome, which is replicated in additional samples. The protective effect of HbS against severe malaria varies greatly according to the parasite genotype at these three loci, suggesting an evolutionary adaptation of parasite populations to host genetic factors.

NATURE (2022)

Article Immunology

Borrelia Infection in Bank Voles Myodes glareolus Is Associated With Specific DQB Haplotypes Which Affect Allelic Divergence Within Individuals

Kristin Scherman et al.

Summary: Pathogen-mediated balancing selection can promote the polymorphism of Major Histocompatibility Complex (MHC) genes through heterozygote advantage, negative frequency-dependent selection (NFDS), and fluctuating selection, potentially involving divergent allele advantage. A study in wild bank voles revealed that individuals with a resistance haplotype had higher allelic divergence, while individuals with a susceptibility haplotype had lower allelic divergence, consistent with selection where divergent allele advantage works in concert with NFDS.

FRONTIERS IN IMMUNOLOGY (2021)

Review Genetics & Heredity

Advances in the Evolutionary Understanding of MHC Polymorphism

Jacek Radwan et al.

TRENDS IN GENETICS (2020)

Review Genetics & Heredity

Host-parasite co-evolution and its genomic signature

Dieter Ebert et al.

NATURE REVIEWS GENETICS (2020)

Article Multidisciplinary Sciences

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

John A. Lees et al.

NATURE COMMUNICATIONS (2019)

Article Ecology

rptR: repeatability estimation and variance decomposition by generalized linear mixed-effects models

Martin A. Stoffel et al.

METHODS IN ECOLOGY AND EVOLUTION (2017)

Article Infectious Diseases

Cross-reactive acquired immunity influences transmission success of the Lyme disease pathogen, Borrelia afzelii

Maxime Jacquet et al.

INFECTION GENETICS AND EVOLUTION (2015)

Article Biology

Within-host competition between Borrelia afzelii ospC strains in wild hosts as revealed by massively parallel amplicon sequencing

Maria Strandh et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2015)

Article Biochemistry & Molecular Biology

Positive Selection on MHC Class II DRB and DQB Genes in the Bank Vole (Myodes glareolus)

Kristin Scherman et al.

JOURNAL OF MOLECULAR EVOLUTION (2014)

Article Biology

Specificity of resistance to dengue virus isolates is associated with genotypes of the mosquito antiviral gene Dicer-2

Louis Lambrechts et al.

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2013)

Article Biology

Polymorphisms at the innate immune receptor TLR2 are associated with Borrelia infection in a wild rodent population

Barbara Tschirren et al.

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2013)

Article Multidisciplinary Sciences

Experimental viral evolution to specific host MHC genotypes reveals fitness and virulence trade-offs in alternative MHC types

Jason L. Kubinak et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Ecology

Distance-based multivariate analyses confound location and dispersion effects

David I. Warton et al.

METHODS IN ECOLOGY AND EVOLUTION (2012)

Review Biology

How pathogens drive genetic diversity: MHC, mechanisms and misunderstandings

Lewis G. Spurgin et al.

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2010)

Article Ecology

Inverse-Gene-for-Gene Infection Genetics and Coevolutionary Dynamics

Andrew Fenton et al.

AMERICAN NATURALIST (2009)

Review Ecology

Generalized linear mixed models: a practical guide for ecology and evolution

Benjamin M. Bolker et al.

TRENDS IN ECOLOGY & EVOLUTION (2009)

Article Evolutionary Biology

Genotype-specific interactions and the trade-off between host and parasite fitness

Lucie Salvaudon et al.

BMC EVOLUTIONARY BIOLOGY (2007)

Article Ecology

Multivariate dispersion as a measure of beta diversity

MJ Anderson et al.

ECOLOGY LETTERS (2006)

Review Microbiology

Fundamental processes in the evolutionary ecology of Lyme borreliosis

Klaus Kurtenbach et al.

NATURE REVIEWS MICROBIOLOGY (2006)

Review Genetics & Heredity

Biological and biomedical implications of the co-evolution of pathogens and their hosts

MEJ Woolhouse et al.

NATURE GENETICS (2002)