Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2022, Issue 37, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.202200588
Keywords
Al3+; Fluorescent bioimaging; Fluorescent sensor; Mechanism; Multidentate ligands
Categories
Funding
- PAICYT [252-CE-2022]
- Facultad de Ciencias Quimicas-UANL
- Ph.D. Program in Molecular Physical Chemistry from University Andres Bello, ANID [3210271]
- FONDECYT [1180565, 1180017, 1201880]
- ANID-Millennium Science Initiative Program [NCN17_040 ANID/FONDAP/15110019]
- Anillos de ciencia y tecnologia [ACT210057]
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This review summarizes the recent advances in multidentate organic compounds as Al3+ fluorescent sensors from an analytical perspective (sensitivity, selectivity), including their applications in fluorescent bioimaging in vitro and in vivo, and photophysical mechanisms.
Aluminium is the most abundant metal in the earth crust and so far, there is no evidence on an important role in the human body. However, the relation of aluminium exposure on human health and aluminium-related diseases is well known. The aim of this review is to summarize the most recent advances on multidentate organic compounds such as naphthalene, coumarin, quinoline, Schiff bases, benzothiazole, benzimidazole, rhodamine, pyrene carbazole, and julolidine derivatives as Al3+ fluorescent sensor starting from an analytical viewpoint (sensibility, selectivity), their application in fluorescent bioimaging in vitro or/and in vivo, and photophysical mechanisms.
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