Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 237, Issue -, Pages -Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2022.114397
Keywords
2-(2-Phenylethyl)chromone; Occurrence; Synthesis; Biological activities
Categories
Funding
- One Thousand Talents Program of Guizhou Province, China [[2019] 4]
- Guizhou Provincial Natural Science Foundation, China [ZK [2021] 027]
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This review mainly focuses on the natural occurrence, chemical synthesis, and biological activities of 2-(2-phenylethyl)chromones (PECs) published up until 2020.
2-(2-Phenylethyl)chromones (PECs) are a group of naturally occurring compounds, which are characterized as phenylethyl substituent at the C2 position of chromone. They have been isolated mainly from Aquilaria sinensis (Lour.) Gilg. This type of natural compound is correlative with anti-diabetes, anticancer, antioxidant, antibacterial, anticancer, and anti-inflammatory activities. Due to the versatile activities of PECs, more and more researchers use different improved methods to synthesize them and their derivatives. This review mainly focuses on the natural occurrence, chemical synthesis, and biological activities of PECs, which were published up until 2020.
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