4.7 Article

Assessment of the inhalation exposure and incremental lifetime cancer risk of PM2.5 bounded polycyclic aromatic hydrocarbons (PAHs) by different toxic equivalent factors and occupancy probability, in the case of Xi'an

Journal

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
Volume 29, Issue 50, Pages 76378-76393

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s11356-022-21061-9

Keywords

PAHs; Different TEFs; Occupancy probabilities; ILCR; Cancer risk

Funding

  1. National Natural Science Foundation of China [41603126]
  2. Natural Science Fundamental Research Plan of Shaanxi Province [2018JQ4004]
  3. Key Laboratory of Aerosol Chemistry and Physics, institute of Earth Environment, CAS [KLACP2003]
  4. Guangdong Provincial Key Laboratory of Utilization and Protection of Environmental Resources [KLEPRU-01]
  5. China Scholarship Council [201906875007]

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This study compared the health risks of Polycyclic aromatic hydrocarbons (PAHs) based on different toxic equivalent factors (TEFs) and focused on the occupancy probability (OP) in polluted areas. The results showed significant differences in calculations using different TEFs and also when considering OP or not. The sensitivity analysis revealed that the cancer slope factor had the greatest impact on health risk assessment during heating periods. The study highlights the importance of establishing correlations between pollution levels and health risks.
Polycyclic aromatic hydrocarbons (PAHs) are widespread toxic pollutants in the atmosphere and have attracted much attention for decades. In this study, we compared the health risks of PAHs based on different toxic equivalent factors (TEFs) in a heavily polluted area during heating and non-heating periods. We also pay attention to occupancy probability (OP) in different polluted areas. The results showed that there were big differences for calculations by different TEFs, and also by OP or not. Age groups except adults were all lower calculated by OP than not. The sensitivity analysis results on the incremental lifetime cancer risks (ILCR) for population groups by Monte Carlo simulation identified that the cancer slope factor extremely affected the health risk assessment in heating periods, followed by daily inhalation exposure levels. However, daily inhalation exposure levels have dominated the effect on the inhalation ILCR and then followed by the cancer slope factor in non-heating periods. The big differences by different calculations investigated that it is important to set up the correlations between the pollution level and health risks, especially for the longtime health assessment.

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