Related references
Note: Only part of the references are listed.Neuronal lineages derived from the nerve-associated Schwann cell precursors
Polina Kameneva et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2021)
Cancer Statistics, 2021
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2021)
Neuroblastoma and the epigenome
Irfete S. Fetahu et al.
CANCER AND METASTASIS REVIEWS (2021)
Pitfalls of Applying Mouse Markers to Human Adrenal Medullary Cells
Gerda Kildisiute et al.
CANCER CELL (2021)
Association of high-risk neuroblastoma classification based on expression profiles with differentiation and metabolism
Shunsuke Kimura et al.
PLOS ONE (2021)
Single-cell atlas of developing murine adrenal gland reveals relation of Schwann cell precursor signature to neuroblastoma phenotype
Evelyn S. Hanemaaijer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Defining Pathological Activities of ALK in Neuroblastoma, a Neural Crest-Derived Cancer
Anna M. Wulf et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
MYCN Function in Neuroblastoma Development
Jorg Otte et al.
FRONTIERS IN ONCOLOGY (2021)
Modeling the developmental origins of pediatric cancer to improve patient outcomes
James F. Amatruda
DISEASE MODELS & MECHANISMS (2021)
Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions
Karin Schmelz et al.
NATURE COMMUNICATIONS (2021)
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell
Gerda Kildisiute et al.
SCIENCE ADVANCES (2021)
Anaplastic lymphoma kinase (alk), a neuroblastoma associated gene, is expressed in neural crest domains during embryonic development of Xenopus
Marcela M. Moreno et al.
GENE EXPRESSION PATTERNS (2021)
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin
Polina Kameneva et al.
NATURE GENETICS (2021)
Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma
Selina Jansky et al.
NATURE GENETICS (2021)
Group phenotypic composition in cancer
Jean-Pascal Capp et al.
ELIFE (2021)
Zebrafish Model of Neuroblastoma Metastasis
Zuag Paj Her et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2021)
Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells
Joachim T. Siaw et al.
CANCERS (2021)
Schwann cell precursors generate sympathoadrenal system during zebrafish development
Dmitrii Kamenev et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2021)
Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
O. C. Bedoya-Reina et al.
NATURE COMMUNICATIONS (2021)
Therapeutic Targeting of the Anaplastic Lymphoma Kinase (ALK) in Neuroblastoma-A Comprehensive Update
Annette K. Brenner et al.
PHARMACEUTICS (2021)
Neuroblastoma and DIPG Organoid Coculture System for Personalized Assessment of Novel Anticancer Immunotherapies
Waleed M. Kholosy et al.
JOURNAL OF PERSONALIZED MEDICINE (2021)
Adult tissue-derived neural crest-like stem cells: Sources, regulatory networks, and translational potential: Concise review
Pihu Mehrotra et al.
STEM CELLS TRANSLATIONAL MEDICINE (2020)
Target gene-independent functions of MYC oncoproteins
Apoorva Baluapuri et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
MYCN amplification and ATRX mutations are incompatible in neuroblastoma
Maged Zeineldin et al.
NATURE COMMUNICATIONS (2020)
Depicting the genetic architecture of pediatric cancers through an integrative gene network approach
Clara Savary et al.
SCIENTIFIC REPORTS (2020)
Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
Malkiel A. Cohen et al.
CELL STEM CELL (2020)
An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity
Camilla Calandrini et al.
NATURE COMMUNICATIONS (2020)
Prognostic significance of MYCN related genes in pediatric neuroblastoma: a study based on TARGET and GEO datasets
Haiwei Wang et al.
BMC PEDIATRICS (2020)
Single-Cell Characterization of Malignant Phenotypes and Developmental Trajectories of Adrenal Neuroblastoma
Rui Dong et al.
CANCER CELL (2020)
Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity
Chia-Lung Yang et al.
Oncotarget (2020)
Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine
Raquel Ferreira et al.
NATURE COMMUNICATIONS (2020)
Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma
Sally L. George et al.
EBIOMEDICINE (2020)
The Tumor Microenvironment in Neuroblastoma: New Players, New Mechanisms of Interaction and New Perspectives
Laurence Blavier et al.
CANCERS (2020)
Comparison of Stage 4 and Stage 4s Neuroblastoma Identifies Autophagy-Related Gene and LncRNA Signatures Associated With Prognosis
Xinyao Meng et al.
FRONTIERS IN ONCOLOGY (2020)
Insights Into the Early Gene Regulatory Network Controlling Neural Crest and Placode Fate Choices at the Neural Border
Subham Seal et al.
FRONTIERS IN PHYSIOLOGY (2020)
Human fetal adrenal cells retain age-related stem- and endocrine-differentiation potential in culture
Giada Poli et al.
FASEB JOURNAL (2019)
Developmental origins and emerging therapeutic opportunities for childhood cancer
Mariella Filbin et al.
NATURE MEDICINE (2019)
Science and health for all children with cancer
Catherine G. Lam et al.
SCIENCE (2019)
Schwann Cell Precursors Generate the Majority of Chromaffin Cells in Zuckerkandl Organ and Some Sympathetic Neurons in Paraganglia
Maria Eleni Kastriti et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)
Comprehensive evaluation of context dependence of the prognostic impact of MYCN amplification in neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project
Kevin Campbell et al.
PEDIATRIC BLOOD & CANCER (2019)
Expression of the Neuroblastoma-Associated ALK-F1174L Activating Mutation During Embryogenesis Impairs the Differentiation of Neural Crest Progenitors in Sympathetic Ganglia
Lucie Vivancos Stalin et al.
FRONTIERS IN ONCOLOGY (2019)
Generation of conditional ALK F1174L mutant mouse models for the study of neuroblastoma pathogenesis
Sachie Ono et al.
GENESIS (2019)
Spatiotemporal structure of cell fate decisions in murine neural crest
Ruslan Soldatov et al.
SCIENCE (2019)
Neural crest stem cells from human epidermis of aged donors maintain their multipotency in vitro and in vivo
Samaneh Moghadasi Boroujeni et al.
SCIENTIFIC REPORTS (2019)
ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures
Zulekha A. Qadeer et al.
CANCER CELL (2019)
WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating
Barbara A. Scholz et al.
NATURE GENETICS (2019)
Compare and contrast: pediatric cancer versus adult malignancies
Patricia Kattner et al.
CANCER AND METASTASIS REVIEWS (2019)
Generation of induced pluripotent stem cell lines from two Neuroblastoma patients carrying a germline ALK R1275Q mutation
Ana Marin Navarro et al.
STEM CELL RESEARCH (2019)
The Evolution of Risk Classification for Neuroblastoma
Elizabeth Sokol et al.
CHILDREN-BASEL (2019)
Tumour heterogeneity and resistance to cancer therapies
Ibiayi Dagogo-Jack et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Spontaneous regression of neuroblastoma
Garrett M. Brodeur
CELL AND TISSUE RESEARCH (2018)
Schwann cell precursor: a neural crest cell in disguise?
Alessandro Furlan et al.
DEVELOPMENTAL BIOLOGY (2018)
The landscape of genomic alterations across childhood cancers
Susanne N. Groebner et al.
NATURE (2018)
Clinical significance of MYCN amplification in patients with high-risk neuroblastoma
Ji Won Lee et al.
PEDIATRIC BLOOD & CANCER (2018)
Risk stratification of high-risk metastatic neuroblastoma: A report from the HR-NBL-1/SIOPEN study
Daniel A. Morgenstern et al.
PEDIATRIC BLOOD & CANCER (2018)
Enhanced expression of MycN/CIP2A drives neural crest toward a neural stem cell-like fate: Implications for priming of neuroblastoma
Laura Kerosuo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus
Sandra G. Gonzalez Malagon et al.
NATURE COMMUNICATIONS (2018)
The Expanding World of N-MYC-Driven Tumors
David S. Rickman et al.
CANCER DISCOVERY (2018)
ALK in Neuroblastoma: Biological and Therapeutic Implications
Ricky M. Trigg et al.
CANCERS (2018)
Neuropilins guide preganglionic sympathetic axons and chromaffin cell precursors to establish the adrenal medulla
Rachael Lumb et al.
DEVELOPMENT (2018)
The molecular basis of neural crest axial identity
Megan Rothstein et al.
DEVELOPMENTAL BIOLOGY (2018)
High-Risk Neuroblastoma Treatment Review
Valeria Smith et al.
CHILDREN-BASEL (2018)
Targeting of epigenetic regulators in neuroblastoma
Luz Jubierre et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2018)
Biological and Genetic Features of Neuroblastoma and their Clinical Importance
Nevim Aygun
CURRENT PEDIATRIC REVIEWS (2018)
Neuroblastoma pathogenesis: deregulation of embryonic neural crest development
Julie A. Tomolonis et al.
CELL AND TISSUE RESEARCH (2018)
Neuroblastoma is composed of two super-enhancer-associated differentiation states
Tim van Groningen et al.
NATURE GENETICS (2017)
Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries
Valentina Boeva et al.
NATURE GENETICS (2017)
Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla
Alessandro Furlan et al.
SCIENCE (2017)
Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon
Jaime Cofre et al.
TheScientificWorldJOURNAL (2017)
Targeting of PHOX2B expression allows the identification of drugs effective in counteracting neuroblastoma cell growth
Eleonora Di Zanni et al.
ONCOTARGET (2017)
ATRX and DAXX: Mechanisms and Mutations
Michael A. Dyer et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon
Jaime Cofre et al.
Scientific World Journal (2017)
Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression
Julian P. Layer et al.
ONCOIMMUNOLOGY (2017)
Microenvironment-Driven Shift of Cohesion/Detachment Balance within Tumors Induces a Switch toward Metastasis in Neuroblastoma
Celine Delloye-Bourgeois et al.
CANCER CELL (2017)
The role of the ALK receptor in cancer biology
B. Hallberg et al.
ANNALS OF ONCOLOGY (2016)
Engineering Stem Cell Organoids
Xiaolei Yin et al.
CELL STEM CELL (2016)
Targeting Suppressive Myeloid Cells Potentiates Checkpoint Inhibitors to Control Spontaneous Neuroblastoma
Yumeng Mao et al.
CLINICAL CANCER RESEARCH (2016)
Stage 4S neuroblastoma tumors show a characteristic DNA methylation portrait
Anneleen Decock et al.
EPIGENETICS (2016)
ALKR1275Q perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN
T. Ueda et al.
ONCOGENE (2016)
Human neural crest cells contribute to coat pigmentation in interspecies chimeras after in utero injection into mouse embryos
Malkiel A. Cohen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Enrichment of Targetable Mutations in the Relapsed Neuroblastoma Genome
Olivia M. Padovan-Merhar et al.
PLOS GENETICS (2016)
Neuroblastoma
Katherine K. Matthay et al.
NATURE REVIEWS DISEASE PRIMERS (2016)
TWIST1 is a direct transcriptional target of MYCN and MYC in neuroblastoma
Abdelkader Selmi et al.
CANCER LETTERS (2015)
Tackling Crizotinib Resistance: The Pathway from Drug Discovery to the Pediatric Clinic
Elizabeth R. Tucker et al.
CANCER RESEARCH (2015)
Mutational dynamics between primary and relapse neuroblastomas
Alexander Schramm et al.
NATURE GENETICS (2015)
Emerging roles of ATRX in cancer
L. Ashley Watson et al.
EPIGENOMICS (2015)
TrkB/BDNF signalling patterns the sympathetic nervous system
Jennifer C. Kasemeier-Kulesa et al.
NATURE COMMUNICATIONS (2015)
Signal Transduction in Cancer
Richard Sever et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2015)
Melanoma
Dirk Schadendorf et al.
NATURE REVIEWS DISEASE PRIMERS (2015)
Tumors of the Neural Crest: Common Themes in Development and Cancer
Lillias H. Maguire et al.
DEVELOPMENTAL DYNAMICS (2015)
A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies
K. Althoff et al.
ONCOGENE (2015)
Retinoic acid signaling pathways in development and diseases
Bhaskar C. Das et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
Pleiotropic effects of fenretinide in neuroblastoma cell lines and multicellular tumor spheroids
Roos Cuperus et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Clinical, Biologic, and Prognostic Differences on the Basis of Primary Tumor Site in Neuroblastoma: A Report From the International Neuroblastoma Risk Group Project
Kieuhoa T. Vo et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Integrated genomic characterization of adrenocortical carcinoma
Guillaume Assie et al.
NATURE GENETICS (2014)
Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma
Alex Cazes et al.
ONCOTARGET (2014)
Targeted Isotretinoin in Neuroblastoma: Kinetics, Genetics, or Absorption
Katherine K. Matthay
CLINICAL CANCER RESEARCH (2013)
Adaptive Dosing Approaches to the Individualization of 13-Cis-Retinoic Acid (Isotretinoin) Treatment for Children with High-Risk Neuroblastoma
Gareth J. Veal et al.
CLINICAL CANCER RESEARCH (2013)
New Strategies in Neuroblastoma: Therapeutic Targeting of MYCN and ALK
Giuseppe Barone et al.
CLINICAL CANCER RESEARCH (2013)
Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma
Damini Chand et al.
DISEASE MODELS & MECHANISMS (2013)
Signatures of mutational processes in human cancer
Ludmil B. Alexandrov et al.
NATURE (2013)
Emerging patterns of somatic mutations in cancer
Ian R. Watson et al.
NATURE REVIEWS GENETICS (2013)
Long-term follow-up of children with high-risk neuroblastoma: The ENSG5 trial experience
Lucas Moreno et al.
PEDIATRIC BLOOD & CANCER (2013)
Distinct Neuroblastoma-associated Alterations of PHOX2B Impair Sympathetic Neuronal Differentiation in Zebrafish Models
Desheng Pei et al.
PLOS GENETICS (2013)
Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
Xiao-Yang Liu et al.
ACTA NEUROPATHOLOGICA (2012)
The ALKF1174L Mutation Potentiates the Oncogenic Activity of MYCN in Neuroblastoma
Teeara Berry et al.
CANCER CELL (2012)
Activated ALK Collaborates with MYCN in Neuroblastoma Pathogenesis
Shizhen Zhu et al.
CANCER CELL (2012)
ATF4 Regulates MYC-Mediated Neuroblastoma Cell Death upon Glutamine Deprivation
Guoliang Qing et al.
CANCER CELL (2012)
Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma
Nai-Kong V. Cheung et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)
Tumor Development, Growth Characteristics and Spectrum of Genetic Aberrations in the TH-MYCN Mouse Model of Neuroblastoma
Agnes Rasmuson et al.
PLOS ONE (2012)
The Dorsal Aorta Initiates a Molecular Cascade That Instructs Sympatho-Adrenal Specification
Daisuke Saito et al.
SCIENCE (2012)
Targeted Expression of Mutated ALK Induces Neuroblastoma in Transgenic Mice
Lukas C. Heukamp et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Tyrosine hydroxylase and regulation of dopamine synthesis
S. Colette Daubner et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)
The effect of P75 on Trk receptors in neuroblastomas
Ruth Ho et al.
CANCER LETTERS (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Optimizing Orthotopic Cell Transplantation in the Mouse Adrenal Gland
Cibele C. Cardoso et al.
CELL TRANSPLANTATION (2010)
Outcomes for Children and Adolescents With Cancer: Challenges for the Twenty-First Century
Malcolm A. Smith et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Medical Progress: Recent Advances in Neuroblastoma.
John M. Maris
NEW ENGLAND JOURNAL OF MEDICINE (2010)
PHOX2B-Mediated Regulation of ALK Expression: In Vitro Identification of a Functional Relationship between Two Genes Involved in Neuroblastoma
Tiziana Bachetti et al.
PLOS ONE (2010)
Structure and function of SWI/SNF chromatin remodeling complexes and mechanistic implications for transcription
Liling Tang et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2010)
MYCN Promotes the Expansion of Phox2B-Positive Neuronal Progenitors to Drive Neuroblastoma Development
Goleeta Alam et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Trk Receptor Expression and Inhibition in Neuroblastomas
Garrett M. Brodeur et al.
CLINICAL CANCER RESEARCH (2009)
Comprehensive Spatiotemporal Analysis of Early Chick Neural Crest Network Genes
Jane Khudyakov et al.
DEVELOPMENTAL DYNAMICS (2009)
The receptor tyrosine kinase RET regulates hindgut colonization by sacral neural crest cells
Jean-Marie Delalande et al.
DEVELOPMENTAL BIOLOGY (2008)
Identification of ALK as a major familial neuroblastoma predisposition gene
Yael P. Mosse et al.
NATURE (2008)
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
David R. Wise et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas
Frank Westermann et al.
GENOME BIOLOGY (2008)
Prevalence and functional consequence of PHOX2B mutations in neuroblastoma
E. H. Raabe et al.
ONCOGENE (2008)
Concerning the Origin of Malignant Tumours by Theodor Boveri. Translated and annotated by Henry Harris
T. Boveri
JOURNAL OF CELL SCIENCE (2007)
Non-transcriptional control of DNA replication by c-Myc
David Dominguez-Sola et al.
NATURE (2007)
CIP2A inhibits PP2A in human malignancies
Melissa R. Junttila et al.
CELL (2007)
N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and P27Kip1 coordinately regulate cerebellar development
Frederique Zindy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Characterization of the expression of the ALK receptor tyrosine kinase in mice
E Vernersson et al.
GENE EXPRESSION PATTERNS (2006)
Common critical pathways in embryogenesis and cancer
FC Kelleher et al.
ACTA ONCOLOGICA (2006)
Inhibition of DNA methyltransferase reverses cisplatin induced drug resistance in murine neuroblastoma cells
YY Qiu et al.
CANCER DETECTION AND PREVENTION (2005)
Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma
D Trochet et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Phox2b controls the development of peripheral chemoreceptors and afferent visceral pathways
S Dauger et al.
DEVELOPMENT (2003)
N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
PS Knoepfler et al.
GENES & DEVELOPMENT (2002)
Trk receptor tyrosine kinases: A bridge between cancer and neural development
A Nakagawara
CANCER LETTERS (2001)
C-cell hyperplasia, pheochromocytoma and sympathoadrenal malformation in a mouse model of multiple endocrine neoplasia type 2B
CL Smith-Hicks et al.
EMBO JOURNAL (2000)
Share Paper
