Journal
DEVELOPING WORLD BIOETHICS
Volume 23, Issue 3, Pages 220-228Publisher
WILEY
DOI: 10.1111/dewb.12359
Keywords
benefits; capacity building; developing countries; HIV vaccine trials; research ethics; Tanzania
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This study aimed to explore the benefits of HIV vaccine trials in Tanzania and examine ethical implications. The findings indicate a growing appreciation of benefits beyond vaccines, including capacity building and other non-capacity-building related benefits.
Debates about what constitutes benefits in human research continue to be less informed due to a lack of empirical evidence from the developing world. This study aimed to explore what constitutes benefits in HIV vaccine trials in Tanzania and examine inherent ethical implications. A qualitative case study design was deployed and a total of 29 purposively selected study participants comprising of experienced researchers, institutional review board members and community advisory board members were included. Collected data were analyzed by thematic analysis aided by computer software: MAXQDA version 20.4.0. The study findings indicate that there is a growing appreciation of benefits beyond actual vaccines to include 1) capacity building at individual, community, institutional and regulatory levels; and 2) non-capacity building related benefits such as strengthened collaborations, ancillary care and employment opportunities. So, as the struggle for viable HIV vaccines continues, other benefits that have accrued from such trials are not to be blindsided especially for developing countries like Tanzania.
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