Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 69, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2022.102161
Keywords
Plasma membrane probes; Fluorescent probes; Lipid probes; Probing; cell surface; Fluorescence microscopy; Super resolution; STED
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Funding
- European Research Council ERC [19-CE29-0005-01, 5D-SURE 21-CE42-0015-04]
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In this paper, the latest advances in fluorescent plasma membrane (PM) probes for chemical and biophysical sensing as well as for super-resolution imaging are reviewed.
Imaging the plasma membrane (PM) by fluorescence techniques using molecular fluorescent probes enable cell segmentation, studying membrane organization and dynamics, formation, and tracking of vesicles. Rational molecular design brings fluorescent PM probes to a new level, providing PM probes with new functions beyond basic PM staining and imaging. We herein review the latest advances in fluorescent PM probes for chemical and biophysical sensing as well as for super-resolution imaging.
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