4.5 Article

Development of a multiciliated cell

Related references

Note: Only part of the references are listed.
Review Cell Biology

Transcriptional regulation of multiciliated cell differentiation

Michael Lewis et al.

Summary: The differentiation program of multiciliated cells is initiated by GEMC1 and MCIDAS, which activate key transcription factors to control the generation of multiple motile cilia. To support this, massive centriole amplification is required, along with the generation of unique deuterosomes and extensive remodeling of the cytoskeleton.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2021)

Article Developmental Biology

A role for Cep70 in centriole amplification in multiciliated cells

Sun K. Kim et al.

Summary: Centriole amplification in multiciliated cells is regulated by a process involving the deuterosome, with the centrosomal protein Cep70 identified as a novel regulator. Cep70 associates with deuterosomes during centriole biogenesis, and depletion of Cep70 leads to a decrease in centriole formation and defects in radial intercalation in multiciliated cells. This suggests that Cep70 plays a crucial role in regulating centriole biogenesis in multiciliated cells.

DEVELOPMENTAL BIOLOGY (2021)

Review Biology

Autonomous clocks that regulate organelle biogenesis, cytoskeletal organization, and intracellular dynamics

Mohammad Mofatteh et al.

Summary: This review explores how cells perceive and use temporal information to regulate their internal processes. The emerging concept of 'autonomous clocks' is introduced, which can function independently but also be influenced by the cell cycle and circadian clock. The authors discuss the roles of these clocks in different scales and complexities, shedding light on their evolutionary significance and potential therapeutic applications.

ELIFE (2021)

Article Biology

Mechanical stretch scales centriole number to apical area via Piezo1 in multiciliated cells

Saurabh Kulkarni et al.

Summary: Cells regulate the number of cilia and centrioles in multiciliated cells (MCCs) through mechanical forces, centrioles, and the mechanosensitive ion channel Piezo1, ensuring optimal cell function. This study provides new insights into organelle number control in cells.

ELIFE (2021)

Article Anatomy & Morphology

A comparative study of the turnover of multiciliated cells in the mouse trachea, oviduct, and brain

Elle C. Roberson et al.

DEVELOPMENTAL DYNAMICS (2020)

Review Developmental Biology

Organelle size scaling over embryonic development

Chase C. Wesley et al.

WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY (2020)

Article Developmental Biology

Scaling of Subcellular Structures

Wallace F. Marshall

Annual Review of Cell and Developmental Biology (2020)

Article Biochemistry & Molecular Biology

Centrioles are amplified in cycling progenitors of olfactory sensory neurons

Kaitlin Ching et al.

PLOS BIOLOGY (2020)

Article Medicine, General & Internal

Motile ciliopathies

Julia Wallmeier et al.

NATURE REVIEWS DISEASE PRIMERS (2020)

Article Biology

Regulation of cilia abundance in multiciliated cells

Rashmi Nanjundappa et al.

ELIFE (2019)

Review Cell Biology

Biology of multiciliated cells

Camille Boutin et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2019)

Article Multidisciplinary Sciences

Dynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors

Olivier Mercey et al.

SCIENTIFIC REPORTS (2019)

Review Cell Biology

Once and only once: mechanisms of centriole duplication and their deregulation in disease

Erich A. Nigg et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Article Multidisciplinary Sciences

Ependymal cilia beating induces an actin network to protect centrioles against shear stress

Alexia Mahuzier et al.

NATURE COMMUNICATIONS (2018)

Article Cell Biology

WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation

Saurabh S. Kulkami et al.

DEVELOPMENTAL CELL (2018)

Article Biology

Cyclin-dependent kinase control of motile ciliogenesis

Eszter K. Vladar et al.

ELIFE (2018)

Article Multidisciplinary Sciences

CDC20B is required for deuterosome-mediated centriole production in multiciliated cell

Diego R. Revinski et al.

NATURE COMMUNICATIONS (2018)

Review Cell Biology

The development and functions of multiciliated epithelia

Nathalie Spassky et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Article Multidisciplinary Sciences

Calibrated mitotic oscillator drives motile ciliogenesis

Adel Al Jord et al.

SCIENCE (2017)

Article Multidisciplinary Sciences

Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis

Munemasa Mori et al.

NATURE COMMUNICATIONS (2017)

Review Biophysics

Cell Geometry: How Cells Count and Measure Size

Wallace F. Marshall

ANNUAL REVIEW OF BIOPHYSICS, VOL 45 (2016)

Article Cell Biology

Multiciliated Cells in Animals

Alice Meunier et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Gmnc Is a Master Regulator of the Multiciliated Cell Differentiation Program

Feng Zhou et al.

CURRENT BIOLOGY (2015)

Article Multidisciplinary Sciences

Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking

Jongshin Kim et al.

NATURE COMMUNICATIONS (2015)

Review Biochemistry & Molecular Biology

Multiciliated Cells

Eric R. Brooks et al.

CURRENT BIOLOGY (2014)

Article Cell Biology

Deuterosome-Mediated Centriole Biogenesis

Deborah A. Klos Dehring et al.

DEVELOPMENTAL CELL (2013)

Editorial Material Cell Biology

Centriole biogenesis in multiciliated cells

Tang K. Tang

NATURE CELL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Microtubules Enable the Planar Cell Polarity of Airway Cilia

Eszter K. Vladar et al.

CURRENT BIOLOGY (2012)

Review Biochemistry & Molecular Biology

Organelle Growth Control through Limiting Pools of Cytoplasmic Components

Nathan W. Goehring et al.

CURRENT BIOLOGY (2012)

Article Multidisciplinary Sciences

Centrosome Loss in the Evolution of Planarians

Juliette Azimzadeh et al.

SCIENCE (2012)

Review Multidisciplinary Sciences

How Cells Know the Size of Their Organelles

Yee-Hung M. Chan et al.

SCIENCE (2012)

Article Cell Biology

Actin and microtubules drive differential aspects of planar cell polarity in multiciliated cells

Michael E. Werner et al.

JOURNAL OF CELL BIOLOGY (2011)

Article Cell Biology

Molecular characterization of centriole assembly in ciliated epithelial cells

Eszter K. Vladar et al.

JOURNAL OF CELL BIOLOGY (2007)

Article Cell Biology

RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1

Jiehong Pan et al.

JOURNAL OF CELL SCIENCE (2007)