Related references
Note: Only part of the references are listed.Homology model, molecular dynamics simulation and novel pyrazole analogs design of Candida albicans CYP450 lanosterol 14-demethylase, a target enzyme for antifungal therapy
Sony K. Jacob et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2017)
Exploring dual inhibitory role of febrifugine analogues against Plasmodium utilizing structure-based virtual screening and molecular dynamic simulation
Rajan Kumar Pandey et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2017)
Probing the interaction mechanism of small molecule inhibitors with matriptase based on molecular dynamics simulation and free energy calculations
Dong-Ru Sun et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2017)
Structural insight into selective phosphodiesterase 4B inhibitors: pharmacophore-based virtual screening, docking, and molecular dynamics simulations
Vidushi Sharma et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2017)
Selective oxidation-reduction and esterification of asiatic acid by Pestalotiopsis microspora and anti-HCV activity
Zhao-Hui Gao et al.
PHYTOCHEMISTRY LETTERS (2017)
Overexpression of Adenylyl Cyclase Encoded by the Mycobacterium tuberculosis Rv2212 Gene Confers Improved Fitness, Accelerated Recovery from Dormancy and Enhanced Virulence in Mice
Margarita O. Shleeva et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)
In Silico Identification of Mimicking Molecules as Defense Inducers Triggering Jasmonic Acid Mediated Immunity against Alternaria Blight Disease in Brassica Species
Rajesh K. Pathak et al.
FRONTIERS IN PLANT SCIENCE (2017)
Asiatic acid ameliorates pulmonary fibrosis induced by bleomycin (BLM) via suppressing pro-fibrotic and inflammatory signaling pathways
Shu-Hong Dong et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
The recovery and protective effects of asiatic acid on differentiated human neuroblastoma SH-SY5Y cells cytotoxic-induced by cholesterol
Kanchanat Ternchoocheep et al.
ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE (2017)
Asiatic acid enhances Nrf2 signaling to protect HepG2 cells from oxidative damage through Akt and ERK activation
Zhimin Qi et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Resazurin-based 96-well plate microdilution method for the determination of minimum inhibitory concentration of biosurfactants
Mohamed Elshikh et al.
BIOTECHNOLOGY LETTERS (2016)
Computer Aided Drug Design: Success and Limitations
Mohammad Hassan Baig et al.
CURRENT PHARMACEUTICAL DESIGN (2016)
Asiatic acid uncouples respiration in isolated mouse liver mitochondria and induces HepG2 cells death
Yapeng Lu et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
Adverse effects of oral second-line antituberculosis drugs in children
H. Simon Schaaf et al.
EXPERT OPINION ON DRUG SAFETY (2016)
Asiatic acid inhibits pulmonary inflammation induced by cigarette smoke
Jae-Won Lee et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2016)
Neuroprotective effect of asiatic acid against spinal cord injury in rats
Wu Jiang et al.
LIFE SCIENCES (2016)
Asiatic acid-pectin hydrogel matrix patch transdermal delivery system influences parasitaemia suppression and inflammation reduction in P-berghei murine malaria infected Sprague-Dawley rats
Greanious Alfred Alfrd Mavondo et al.
ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE (2016)
Synthesis and biological evaluation of novel asiatic acid derivatives with anticancer activity
Bruno M. F. Goncalves et al.
RSC ADVANCES (2016)
Crystal structures of Mycobacterium tuberculosis GlgE and complexes with non-covalent inhibitors
Jared J. Lindenberger et al.
SCIENTIFIC REPORTS (2015)
Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism
Vitor Mendes et al.
SCIENTIFIC REPORTS (2015)
Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo
Chandagirikoppal V. Kavitha et al.
MOLECULAR CARCINOGENESIS (2015)
Apoptosis of HL-60 human leukemia cells induced by Asiatic acid through modulation of B-cell lymphoma 2 family proteins and the mitogen-activated protein kinase signaling pathway
Qiuling Wu et al.
MOLECULAR MEDICINE REPORTS (2015)
Antibacterial effects and action modes of asiatic acid
Wen-hu Liu et al.
BIOMEDICINE-TAIWAN (2015)
Synthesis of a C-phosphonate mimic of maltose-1-phosphate and inhibition studies on Mycobacterium tuberculosis GlgE
Sri Kumar Veleti et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
Synthesis of a Poly-hydroxypyrolidine-Based inhibitor of Mycobacterium tuberculosis GlgE
Sri Kumar Veleti et al.
JOURNAL OF ORGANIC CHEMISTRY (2014)
GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit
Sander Pronk et al.
BIOINFORMATICS (2013)
NPACT: Naturally Occurring Plant-based Anti-cancer Compound-Activity-Target database
Manu Mangal et al.
NUCLEIC ACIDS RESEARCH (2013)
Asiatic acid, a pentacyclic triterpene in Centella asiatica, attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells
Min-fang Xu et al.
ACTA PHARMACOLOGICA SINICA (2012)
Structure of Streptomyces Maltosyltransferase GlgE, a Homologue of a Genetically Validated Anti-tuberculosis Target
Karl Syson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Molecular Dynamics Simulations and QM/MM Studies of the Reactivation by 2-PAM of Tabun Inhibited Human Acethylcolinesterase
Arlan da Silva Goncalves et al.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY (2011)
Unexpected and widespread connections between bacterial glycogen and trehalose metabolism
Govind Chandra et al.
MICROBIOLOGY-SGM (2011)
TCM Database@Taiwan: The World's Largest Traditional Chinese Medicine Database for Drug Screening In Silico
Calvin Yu-Chian Chen
PLOS ONE (2011)
Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery
Sean Ekins et al.
TRENDS IN MICROBIOLOGY (2011)
THE SIGNIFICANCE OF GLGE AS A NEW TARGET FOR TUBERCULOSIS
Rainer Kalscheuer et al.
DRUG NEWS & PERSPECTIVES (2010)
Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an α-glucan pathway
Rainer Kalscheuer et al.
NATURE CHEMICAL BIOLOGY (2010)
In vivo antifungal effect of Combretum and Terminalia species extracts on cutaneous wound healing in immunosuppressed rats
P. Masoko et al.
PHARMACEUTICAL BIOLOGY (2010)
Synthesis and Biological Evaluation of Asiatic Acid Derivatives as Inhibitors of Glycogen Phosphorylases
Liying Zhang et al.
CHEMISTRY & BIODIVERSITY (2009)
AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility
Garrett M. Morris et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Comparative structural analyses of the α-glucan and glycogen from Mycobacterium bovis
Premkumar Dinadayala et al.
GLYCOBIOLOGY (2008)
Alisiaquinones and alisiaquinol, dual inhibitors of Plasmodium falciparum enzyme targets from a New Caledonian deep water sponge
Denis Desoubzdanne et al.
JOURNAL OF NATURAL PRODUCTS (2008)
Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice
Tounkang Sambou et al.
MOLECULAR MICROBIOLOGY (2008)
Cell wall-associated alpha-glucan is instrumental for Mycobacterium tuberculosis to block CD1 molecule expression and disable the function of dendritic cell derived from infected monocyte
Maria Cristina Gagliardi et al.
CELLULAR MICROBIOLOGY (2007)
Isoniazid induces its own resistance in nonreplicating Mycobacterium tuberculosis
Salman Siddiqi et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
Disruption of the endoplasmic reticulum and increases in cytoplasmic calcium are early events in cell death induced by the natural triterpenoid Asiatic acid
Debbie M. Gurfinkel et al.
APOPTOSIS (2006)
Natural products - The future scaffolds for novel antibiotics?
MS Butler et al.
BIOCHEMICAL PHARMACOLOGY (2006)
Predictive model of blood-brain barrier penetration of organic compounds
XL Ma et al.
ACTA PHARMACOLOGICA SINICA (2005)
Isoniazid resistance of exponentially growing Mycobacterium smegmatis biofilm culture
R Teng et al.
FEMS MICROBIOLOGY LETTERS (2003)
Isolation and characterization of Caco-2 subclones expressing high levels of multidrug resistance protein efflux transporter
K Horie et al.
PHARMACEUTICAL RESEARCH (2003)
Resazurin microtiter assay plate testing of Mycobacterium tuberculosis susceptibilities to second-line drugs: Rapid, simple, and inexpensive method
A Martin et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure-activity relationship (QSAR) with the Abraham descriptors
YH Zhao et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2001)
Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells
S Yamashita et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2000)