4.7 Article

Pitting behavior of 316L stainless steel in direct culture with mesenchymal stem cells

Journal

CORROSION SCIENCE
Volume 204, Issue -, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.corsci.2022.110380

Keywords

A; Stainless steel; B; EIS; Polarization; C; Pitting corrosion

Funding

  1. National Natural Science Foundation of China [21734002, 51825302, 52021004]
  2. Natural Science Foundation of Chongqing [cstc2021jcyj-cxttX0002]
  3. State Key Project of Research and Development [2017YFB0702603, 2016YFC1100300]
  4. China Postdoctoral Science Foundation [2021M693707]

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Corrosion is a major reason for the failure of metallic implants. The presence of bone marrow derived mesenchymal stem cells (BMSCs) can decrease the stability of 316 L stainless steels (316 L SS), leading to preferential pitting corrosion initiation at the peripheries of BMSCs.
Corrosion is one of the dominating reasons for failure of metallic implants. The corrosion behavior of the 316 L stainless steels (316 L SS) in direct culture with bone marrow derived mesenchymal stem cells (BMSCs) was studied via electrochemical measurements. The adhesion, proliferation and apoptosis of BMSCs could be detected by electrochemical impedance spectroscopy (EIS). The presence of BMSCs could decline the stability of the passive films and lower the pitting potential of the 316 L SS. The pitting corrosion preferentially initiated at the peripheries of the BMSCs, which was driven by surface overpotential potential generated from the negative transmembrane potential.

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