4.7 Review

A review: The detection of cancer cells in histopathology based on machine vision

Journal

COMPUTERS IN BIOLOGY AND MEDICINE
Volume 146, Issue -, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.compbiomed.2022.105636

Keywords

Machine vision; Traditional machine learning; Deep learning; Histopathological images; Cancer cell detection; Image preprocessing and segmentation; Feature extraction; Classification

Funding

  1. Key scientific and technological projects in Henan Province in 2020 [202102210395]
  2. Scientific and Technological Innovation Team of Colleges and Universities in Henan Province in 2020 [20IRTSTHN015]
  3. Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program [2017BT01G167]

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Machine vision plays a crucial role in cancer cell pathology detection. This paper reviews the use of machine vision in detecting cancer cells in histopathology images, as well as the benefits and drawbacks of various detection approaches. The future development tendency is discussed and forecasted to guide future research.
Machine vision is being employed in defect detection, size measurement, pattern recognition, image fusion, target tracking and 3D reconstruction. Traditional cancer detection methods are dominated by manual detection, which wastes time and manpower, and heavily relies on the pathologists' skill and work experience. Therefore, these manual detection approaches are not convenient for the inheritance of domain knowledge, and are not suitable for the rapid development of medical care in the future. The emergence of machine vision can iteratively update and learn the domain knowledge of cancer cell pathology detection to achieve automated, high-precision, and consistent detection. Consequently, this paper reviews the use of machine vision to detect cancer cells in histopathology images, as well as the benefits and drawbacks of various detection approaches. First, we review the application of image preprocessing and image segmentation in histopathology for the detection of cancer cells, and compare the benefits and drawbacks of different algorithms. Secondly, for the characteristics of histopathological cancer cell images, the research progress of shape, color and texture features and other methods is mainly reviewed. Furthermore, for the classification methods of histopathological cancer cell images, the benefits and drawbacks of traditional machine vision approaches and deep learning methods are compared and analyzed. Finally, the above research is discussed and forecasted, with the expected future development tendency serving as a guide for future research.

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