Association between computerized tomography (CT) study of body composition and severity of acute pancreatitis: Use of a novel Z-score supports obesity paradox

Article Nutrition & Dietetics

Establishment of normative biometric data for body composition based on computed tomography in a North American cohort

P. J. Navin et al.

Summary: This study utilized CT data to determine age and sex specific distribution of body composition, providing important reference for future research and clinical practice.

CLINICAL NUTRITION (2021)

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Article Multidisciplinary Sciences

Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox

Biswajit Khatua et al.

Summary: The obesity paradox, observed mainly in reports from the Western Hemisphere, suggests that increased severity of acute pancreatitis is associated with higher proportion of unsaturated fat intake in leaner populations. Studies in mice showed that unsaturated visceral triglyceride hydrolysis caused worse organ failure during pancreatitis, despite the mice being leaner compared to those with saturated triglyceride intake.

SCIENCE ADVANCES (2021)

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Review Gastroenterology & Hepatology