4.6 Article

Detecting motor unit abnormalities in amyotrophic lateral sclerosis using high-density surface EMG

Related references

Note: Only part of the references are listed.
Article Neurosciences

Identification of the laterality of motor unit behavior in female patients with parkinson's disease using high-density surface electromyography

Yuichi Nishikawa et al.

Summary: Patients with Parkinson's disease (PD) exhibit greater laterality of muscle contraction properties compared to other parkinsonism diseases, with abnormalities in single motor unit behavior even in early stages of the disease. This highlights the importance of detecting abnormal muscle properties in PD patients early on.

EUROPEAN JOURNAL OF NEUROSCIENCE (2021)

Article Neurosciences

Deficit in knee extension strength following anterior cruciate ligament reconstruction is explained by a reduced neural drive to the vasti muscles

Stefano Nuccio et al.

Summary: The study found that individuals who underwent ACLR had lower maximum voluntary isometric force, reduced MU discharge rates, lower absolute MU recruitment and derecruitment thresholds, and lower input-output gain of motoneurons on the reconstructed side compared to the contralateral side. These deficits in MU properties were associated with deficits in maximum voluntary isometric force, indicating that mid- to long-term strength deficits following ACLR may be due to reduced neural drive to the vasti muscles.

JOURNAL OF PHYSIOLOGY-LONDON (2021)

Article Chemistry, Analytical

Association between the Degree of Pre-Synaptic Dopaminergic Pathway Degeneration and Motor Unit Firing Behavior in Parkinson's Disease Patients

Yuichi Nishikawa et al.

Summary: The study revealed a moderate-to-strong correlation between degeneration of dopaminergic pathways and MU firing behavior in PD patients, indicating that abnormalities in MU activity can be used to predict central nervous system degeneration following PD.

SENSORS (2021)

Article Neurosciences

Time Course of Alterations in Adult Spinal Motoneuron Properties in the SOD1(G93A) Mouse Model of ALS

Seoan Huh et al.

Summary: The excitability of spinal motoneurons in ALS patients is initially maintained by pushing some cells far above the normal range of conductances, but as the disease progresses, conductances shrink below normal values in surviving cells. This shrinkage may promote survival and indicate that large conductances contribute to degeneration.

ENEURO (2021)

Article Nutrition & Dietetics

Fish Protein Ingestion Induces Neural, but Not Muscular Adaptations, Following Resistance Training in Young Adults

Kohei Watanabe et al.

Summary: The study found that consuming fish protein and undergoing resistance training can alter neural and muscular adaptations in young adults.

FRONTIERS IN NUTRITION (2021)

Article Neurosciences

First-recruited motor units adopt a faster phenotype in amyotrophic lateral sclerosis

Thomas Weddell et al.

Summary: This study utilized high-density surface electromyography (HDSEMG) to investigate motor unit firing patterns in different stages of ALS, revealing that first-recruited motor units in the later stages of the disease develop a faster phenotype, possibly due to the selective loss of vulnerable fast-twitch motor units. Inhibiting this potentially maladaptive phenotypic drift may protect the longevity of the motor unit pool, offering a novel therapeutic avenue.

JOURNAL OF PHYSIOLOGY-LONDON (2021)

Article Neurosciences

Changes in neural drive to calf muscles during steady submaximal contractions after repeated static stretches

Melissa R. Mazzo et al.

Summary: Repeated static-stretching interventions consistently increase joint range of motion and decrease total joint stiffness. Changes in muscle and connective-tissue properties are mixed, but adjustments in motor unit activity are necessary at low forces after static stretches to accommodate reductions in muscle-tendon unit capabilities. The influence of static stretching on muscle-tendon unit function and muscle activation remains unclear.

JOURNAL OF PHYSIOLOGY-LONDON (2021)

Article Neurosciences

Estimates of persistent inward currents are reduced in upper limb motor units of older adults

Altamash S. Hassan et al.

Summary: Ageing is a natural process that causes changes in the neuromuscular system, leading to a reduced quality of life. Persistent inward currents play a crucial role in the neural control of human movement, influenced by monoamines from the brainstem. Estimates of persistent inward currents are reduced in older adults compared to younger individuals, suggesting a potential mechanism for reduced firing rates in the older population.

JOURNAL OF PHYSIOLOGY-LONDON (2021)

Article Engineering, Biomedical

Impact of parameter selection on estimates of motoneuron excitability using paired motor unit analysis

Altamash Hassan et al.

JOURNAL OF NEURAL ENGINEERING (2020)

Article Neurosciences

The effect of medication on vastus lateralis muscle activation patterns in Parkinson's disease patients

Yuichi Nishikawa et al.

JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY (2018)

Article Neurosciences

Tracking motor units longitudinally across experimental sessions with high-density surface electromyography

E. Martinez-Valdes et al.

JOURNAL OF PHYSIOLOGY-LONDON (2017)

Review Medicine, General & Internal

Amyotrophic lateral sclerosis

Michael A. van Es et al.

LANCET (2017)

Review Clinical Neurology

Lower motor neuron dysfunction in ALS

Mamede de Carvalho et al.

CLINICAL NEUROPHYSIOLOGY (2016)

Article Public, Environmental & Occupational Health

Prevalence and Incidence of Amyotrophic Lateral Sclerosis in Japan

Yuriko Doi et al.

JOURNAL OF EPIDEMIOLOGY (2014)

Article Clinical Neurology

Reach task-associated excitatory overdrive of motor cortical neurons following infusion with ALS-CSF

R. Sankaranarayani et al.

JOURNAL OF NEURAL TRANSMISSION (2014)

Article Clinical Neurology

CHANGES IN MOTOR UNIT PROPERTIES IN SOD1 (G93A) RATS

Katarzyna Krysciak et al.

MUSCLE & NERVE (2014)

Review Clinical Neurology

Transcranial magnetic stimulation and amyotrophic lateral sclerosis: pathophysiological insights

Steve Vucic et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2013)

Review Clinical Neurology

Awaji Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis A Systematic Review

Joao Costa et al.

ARCHIVES OF NEUROLOGY (2012)

Article Clinical Neurology

Motor unit firing in amyotrophic lateral sclerosis and other upper and lower motor neurone disorders

Mamede de Carvalho et al.

CLINICAL NEUROPHYSIOLOGY (2012)

Article Neurosciences

Task-dependent spatial distribution of neural activation pattern in human rectus femoris muscle

Kohei Watanabe et al.

JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY (2012)

Article Physiology

Motor Unit

C. J. Heckman et al.

COMPREHENSIVE PHYSIOLOGY (2012)

Review Neurosciences

Human motor unit recordings: Origins and insight into the integrated motor system

Jacques Duchateau et al.

BRAIN RESEARCH (2011)

Article Engineering, Biomedical

Accuracy assessment of CKC high-density surface EMG decomposition in biceps femoris muscle

H. R. Marateb et al.

JOURNAL OF NEURAL ENGINEERING (2011)

Article Neurosciences

Motoneuron afterhyperpolarisation duration in amyotrophic lateral sclerosis

Maria Piotrkiewicz et al.

JOURNAL OF PHYSIOLOGY-LONDON (2011)

Article Medicine, General & Internal

Amyotrophic lateral sclerosis

Matthew C. Kiernan et al.

LANCET (2011)

Article Engineering, Biomedical

Experimental Analysis of Accuracy in the Identification of Motor Unit Spike Trains From High-Density Surface EMG

Ales Holobar et al.

IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING (2010)

Article Clinical Neurology

Estimating motor unit discharge patterns from high-density surface electromyogram

Ales Holobar et al.

CLINICAL NEUROPHYSIOLOGY (2009)

Review Clinical Neurology

Electrodiagnostic criteria for diagnosis of ALS

Mamede de Carvalho et al.

CLINICAL NEUROPHYSIOLOGY (2008)

Article Neurosciences

Analysis of motor units with high-density surface electromyography

Roberto Merletti et al.

JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY (2008)

Article Neurosciences

Age-related change in duration of afterhyperpolarization of human motoneurones

M. Piotrkiewicz et al.

JOURNAL OF PHYSIOLOGY-LONDON (2007)

Article Orthopedics

Recruitment patterns in human skeletal muscle during electrical stimulation

CM Gregory et al.

PHYSICAL THERAPY (2005)

Article Computer Science, Interdisciplinary Applications

Correlation-based decomposition of surface electromyograms at low contraction forces

A Holobar et al.

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING (2004)

Article Neurosciences

Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice

JJ Kuo et al.

JOURNAL OF NEUROPHYSIOLOGY (2004)

Article Neurosciences

Intrinsic activation of human motoneurons: Possible contribution to motor unit excitation

M Gorassini et al.

JOURNAL OF NEUROPHYSIOLOGY (2002)