Theoretical Perspectives in Organocatalysis

It is clear that the field of organocatalysis is continuously expanding during the last decades. With increasing computational capacity and new techniques, computational methods have provided a more economic approach to explore different chemical systems. This review offers a broad yet concise overview of current state-of-the-art studies that have employed novel strategies for catalyst design. The evolution of the all different theoretical approaches most commonly used within organocatalysis is discussed, from the traditional approach, manual-driven, to the most recent one, machine-driven.

Automated summary

This review provides a comprehensive overview of the expanding field of organocatalysis and the novel strategies employed in catalyst design. Computational methods have emerged as a more economical approach for exploring different chemical systems. The review discusses the evolution of theoretical approaches in organocatalysis, from traditional manual-driven methods to the recent machine-driven ones.