4.7 Article

3D printed PCLA scaffold with nano-hydroxyapatite coating doped green tea EGCG promotes bone growth and inhibits multidrug-resistant bacteria colonization

Related references

Note: Only part of the references are listed.
Article Engineering, Biomedical

A Hierarchical-Structured Mineralized Nanofiber Scaffold with Osteoimmunomodulatory and Osteoinductive Functions for Enhanced Alveolar Bone Regeneration

Yang He et al.

Summary: The mineralized nanofiber scaffold promotes osteogenic differentiation of bone mesenchymal stem cells and stimulates macrophage polarization towards a pro-healing phenotype, enhancing bone regeneration in the alveolar bone defect repair.

ADVANCED HEALTHCARE MATERIALS (2022)

Article Chemistry, Multidisciplinary

Qualitative and Quantitative Analysis of Tumor Cell Invasion Using Au Clusters

Xiangchun Zhang et al.

Summary: A method utilizing red fluorescent gold clusters was developed for distinguishing the invasion/metastasis risk of cervical cancer cells by labeling MT1-MMP, allowing for visualization and quantification using fluorescence microscopy and ICP-MS. This method has the potential to accurately diagnose aggressive tumor cells and assess their invasion/metastasis risk.

NANOMATERIALS (2022)

Article Chemistry, Applied

Chitosan-coated hydroxyapatite and drug-loaded polytrimethylene carbonate/polylactic acid scaffold for enhancing bone regeneration

Jian He et al.

Summary: A chitosan-coated microsphere scaffold was fabricated for bone regeneration, showing excellent biocompatibility and controlled drug release. The incorporation of PLLA, OA-HA, and VH into the scaffold slowed biodegradability while enhancing mechanical and surface properties. CS coating promoted osteoblast adhesion, and the release of OA-HA stimulated osteogenic proliferation.

CARBOHYDRATE POLYMERS (2021)

Review Engineering, Biomedical

3D and 4D printing in dentistry and maxillofacial surgery: Printing techniques, materials, and applications

Danial Khorsandi et al.

Summary: 3D and 4D printing technologies enable precise and expedited manufacturing of a wide range of objects, including those used in dentistry such as surgical drill guides, crowns, bridges, and implants. This review highlights the available 3D printing technologies and materials in dentistry, as well as recent applications to show the progress in this field.

ACTA BIOMATERIALIA (2021)

Article Engineering, Biomedical

Matrix metalloproteinase (MMP)-degradable tissue engineered periosteum coordinates allograft healing via early stage recruitment and support of host neurovasculature

Yiming Li et al.

Summary: Decellularized allografts, commonly used for critical size bone defects, have high long-term failure rates due to lack of periosteum. Recent studies show that MMP-TEP modified allografts can effectively coordinate host neurovasculature, leading to improved bone healing outcomes.

BIOMATERIALS (2021)

Article Chemistry, Multidisciplinary

Copper Clusters: An Effective Antibacterial for Eradicating Multidrug-Resistant Bacterial Infection In Vitro and In Vivo

Xiangchun Zhang et al.

Summary: CuCs is a novel antibacterial molecule with broad-spectrum and excellent antibacterial activity, able to disrupt bacterial wall structure, regulate GSH/GSSG ratio, induce reactive oxygen species production, and ultimately lead to bacterial death. In vivo studies in mice demonstrate that CuCs can significantly treat skin wound infections and sepsis caused by MRSA, with similar therapeutic efficacy as mupirocin ointment and vancomycin. Compared to silver and platinum clusters, CuCs show extremely low cytotoxicity to normal mammalian cells.

ADVANCED FUNCTIONAL MATERIALS (2021)

Article Food Science & Technology

Hepatotoxicity of Pyrrolizidine Alkaloid Compound Intermedine: Comparison with Other Pyrrolizidine Alkaloids and Its Toxicological Mechanism

Ziqi Wang et al.

Summary: This study revealed the hepatotoxic mechanism of herbal medicines containing pyrrolizidine alkaloids, showing that these compounds induce cell apoptosis by generating excessive reactive oxygen species and changing mitochondrial membrane potential. This study provided direct evidence of Intermedine inducing hepatotoxicity through mitochondria-mediated apoptosis, enhancing the understanding of PA toxicity.

TOXINS (2021)

Article Chemistry, Multidisciplinary

An Antibacterial Nanorobotic Approach for the Specific Targeting and Removal of Multiple Drug-Resistant Staphylococcus aureus

Nayab Batool et al.

Summary: A resistance-free antibacterial nanorobot was developed to specifically capture and kill MRSA, achieving a 99.999% bacterial removal rate under RF-EMS signal. In vivo efficacy was proven in a mice subcutaneous skin infection model.

SMALL (2021)

Article Chemistry, Multidisciplinary

Enhanced bone regeneration using poly(trimethylene carbonate)/vancomycin hydrochloride porous microsphere scaffolds in presence of the silane coupling agent modified hydroxyapatite nanoparticles

Jian He et al.

Summary: A novel PTMC/KHA/VH scaffold with unique surface properties and high cytocompatibility was synthesized, and after treating rat femur defects, it was found to significantly reduce inflammation response and promote bone regeneration.

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY (2021)

Article Food Science & Technology

Potential protective mechanisms of green tea polyphenol EGCG against COVID-19

Zhichao Zhang et al.

Summary: EGCG may have protective effects against COVID-19 through multiple pathways, including inhibiting virus entry into cells, suppressing viral replication, reducing oxidative stress, and preventing cytokine storms. Further studies in animals and humans are needed to validate these findings.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

Article Materials Science, Biomaterials

3D Printing of Antibacterial, Biocompatible, and Biomimetic Hybrid Aerogel-Based Scaffolds with Hierarchical Porosities via Integrating Antibacterial Peptide-Modified Silk Fibroin with Silica Nanostructure

Nighat Karamat-Ullah et al.

Summary: Scaffold-mediated tissue engineering is crucial for bone tissue regeneration, necessitating careful consideration of biological, microstructural, and mechanical properties. This study developed an antibacterial and biocompatible silica-silk fibroin (SF) gel-based ink for creating three-dimensional hybrid aerogel-based scaffolds, showing promising properties for repairing bone defects.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2021)

Review Polymer Science

Polymer scaffolds as drug delivery systems

Italo Rodrigo Calori et al.

EUROPEAN POLYMER JOURNAL (2020)

Review Nanoscience & Nanotechnology

Materials design for bone-tissue engineering

Gerry L. Koons et al.

NATURE REVIEWS MATERIALS (2020)

Review Chemistry, Multidisciplinary

Biomimetic micro/nano structures for biomedical applications

Tao Xiang et al.

NANO TODAY (2020)

Review Nanoscience & Nanotechnology

Shaping and structuring supramolecular gels

Phillip R. A. Chivers et al.

NATURE REVIEWS MATERIALS (2019)

Review Engineering, Biomedical

Three-dimensional (3D) printed scaffold and material selection for bone repair

Lei Zhang et al.

ACTA BIOMATERIALIA (2019)

Article Engineering, Biomedical

Vascularized 3D printed scaffolds for promoting bone regeneration

Yufei Yan et al.

BIOMATERIALS (2019)

Article Medicine, General & Internal

Synthesis and Evaluation of BMMSC-seeded BMP-6/nHAG/GMS Scaffolds for Bone Regeneration

Xuewen Li et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2019)

Review Materials Science, Biomaterials

Bioinks for 3D bioprinting: an overview

P. Selcan Gungor-Ozkerim et al.

BIOMATERIALS SCIENCE (2018)

Review Engineering, Biomedical

3D bioprinting: an emerging technology full of opportunities and challenges

Bin Zhang et al.

BIO-DESIGN AND MANUFACTURING (2018)

Article Engineering, Biomedical

3D-printed vascular networks direct therapeutic angiogenesis in ischaemia

T. Mirabella et al.

NATURE BIOMEDICAL ENGINEERING (2017)

Review Biophysics

An overview of hydrogel-based intra-articular drug delivery for the treatment of osteoarthritis

Zhiwei He et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

Review Biochemistry & Molecular Biology

Osteogenic Differentiation in Healthy and Pathological Conditions

Maria Teresa Valenti et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Review Dentistry, Oral Surgery & Medicine

Regenerative Medicine for Periodontal and Peri-implant Diseases

L. Larsson et al.

JOURNAL OF DENTAL RESEARCH (2016)

Article Engineering, Biomedical

3D-Printed Biodegradable Polymeric Vascular Grafts

Anthony J. Melchiorri et al.

ADVANCED HEALTHCARE MATERIALS (2016)

Article Engineering, Biomedical

Polyetheretherketone (PEEK) for medical applications

Ivan Vladislavov Panayotov et al.

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2016)

Review Pharmacology & Pharmacy

Thermoresponsive hydrogels in biomedical applications A seven-year update

Leda Klouda

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2015)

Article Engineering, Biomedical

Scaffold-based Anti-infection Strategies in Bone Repair

Christopher T. Johnson et al.

ANNALS OF BIOMEDICAL ENGINEERING (2015)

Article Cell & Tissue Engineering

BIODEGRADABLE ANTIBIOTIC-IMPREGNATED SCAFFOLD TO PREVENT OSTEOMYELITIS IN A CONTAMINATED IN VIVO BONE DEFECT MODEL

J. S. McLaren et al.

EUROPEAN CELLS & MATERIALS (2014)

Review Infectious Diseases

MRSA: the first half century

Robert C. Moellering

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2012)

Article Engineering, Biomedical

The pro-angiogenic properties of multi-functional bioactive glass composite scaffolds

Lutz-Christian Gerhardt et al.

BIOMATERIALS (2011)

Article Engineering, Biomedical

Influence of meniscectomy and meniscus replacement on the stress distribution in human knee joint

Ashkan Vaziri et al.

ANNALS OF BIOMEDICAL ENGINEERING (2008)

Review Engineering, Biomedical

Porosity of 3D biomaterial scaffolds and osteogenesis

V Karageorgiou et al.

BIOMATERIALS (2005)