Journal
CELL METABOLISM
Volume 34, Issue 6, Pages 801-802Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2022.05.006
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Funding
- Canadian Cancer Society Impact Grant [706694]
- CIHR Foundation [FRN 159925]
- Canada Research Chair Program CRC Tier One in Human Stem Cell Biology
- Michael G. DeGroote Chair in Stem Cell Biology
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In this study, Liu et al. show that Prmt7 can regulate the onset and progression of leukemia by inhibiting the self-renewal capacity of leukemic stem cells (LSCs) in a mouse model of chronic myeloid leukemia (CML).
In this issue of Cell Metabolism, Liu et al. demonstrate that Prmt7 can regulate the onset and progression of leukemogenesis by inhibiting self-renewal capacity of leukemic stem cells (LSCs) as modeled in a murine version of chronic myeloid leukemia (CML).
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