Cryo-electron tomography: A long journey to the inner space of cells

Cryogenic electron tomography (cryo-ET) is the application of tomographic principles of data acquisition and reconstruction to frozen-hydrated biological specimens. It combines a close-to-life preservation of cellular structures with the power of high-resolution three-dimensional imaging, which allows us to study the molecular architecture of cells, or their molecular sociology, in unprecedented detail.

Automated summary

Cryo-ET combines close-to-life preservation of cellular structures with high-resolution three-dimensional imaging, allowing us to study the molecular architecture and molecular sociology of cells in unprecedented detail.