Journal
CELL
Volume 185, Issue 15, Pages 2649-2652Publisher
CELL PRESS
DOI: 10.1016/j.cell.2022.06.034
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Cryo-ET combines close-to-life preservation of cellular structures with high-resolution three-dimensional imaging, allowing us to study the molecular architecture and molecular sociology of cells in unprecedented detail.
Cryogenic electron tomography (cryo-ET) is the application of tomographic principles of data acquisition and reconstruction to frozen-hydrated biological specimens. It combines a close-to-life preservation of cellular structures with the power of high-resolution three-dimensional imaging, which allows us to study the molecular architecture of cells, or their molecular sociology, in unprecedented detail.
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