Journal
CELL
Volume 185, Issue 16, Pages 2846-2848Publisher
CELL PRESS
DOI: 10.1016/j.cell.2022.06.033
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This research has further revealed the interaction mechanism between neural circuits and glioblastoma, highlighting the importance of neuron-to-glioma synaptic communication in glioma invasion.
Glioblastoma is a lethal, diffusely invasive brain cancer that is robustly regulated by the activity of the brain itself, in part through neuron-to-glioma synaptic communication. Venkataramani et al. have conceptually advanced understanding of glioblastoma interactions with neural circuits, demonstrating that conduction of electrochemical signals via neuron-to-glioma synapses drives glioma invasion.
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