4.1 Review

Reinventing HCV Treatment: Past and Future Perspectives

Journal

JOURNAL OF CLINICAL PHARMACOLOGY
Volume 57, Issue 3, Pages 287-296

Publisher

WILEY
DOI: 10.1002/jcph.830

Keywords

hepatitis C; direct-acting antivirals; genotype; sustained virologic response; resistance-associated variants

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This review paper summarizes the epidemiology of hepatitis C virus (HCV) and chronic HCV infection, including HCV virology and treatment regimens. Specifically, we focus on the evolution of past, current, and future HCV treatment options, the reasons for treatment failure, and the impact of resistanceassociated variants on treatment success.

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