Related references
Note: Only part of the references are listed.Cancer statistics, 2022
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2022)
Dual CRISPR interference and activation for targeted reactivation of X-linked endogenous FOXP3 in human breast cancer cells
Xuelian Cui et al.
MOLECULAR CANCER (2022)
Targeting RLIP with CRISPR/Cas9 controls tumor growth
Jyotsana Singhal et al.
CARCINOGENESIS (2021)
Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy
Hibah Shaath et al.
CELL DEATH DISCOVERY (2021)
RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
Jasmine George et al.
CELL REPORTS (2021)
CRISPR/dCas9-Based Systems: Mechanisms and Applications in Plant Sciences
Chou Khai Soong Karlson et al.
PLANTS-BASEL (2021)
Versatile modification of the CRISPR/Cas9 ribonucleoprotein system to facilitate in vivo application
Bixi Sun et al.
JOURNAL OF CONTROLLED RELEASE (2021)
In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy
Meiou Dai et al.
NATURE COMMUNICATIONS (2021)
CRISPR/Cas9 based genome editing for targeted transcriptional control in triple-negative breast cancer
Desh Deepak Singh et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2021)
New insights on CRISPR/Cas9-based therapy for breast Cancer
Hussein Sabit et al.
GENES AND ENVIRONMENT (2021)
Cdk5 knocking out mediated by CRISPR-Cas9 genome editing for PD-L1 attenuation and enhanced antitumor immunity
Huan Deng et al.
ACTA PHARMACEUTICA SINICA B (2020)
Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers
Bowen Sun et al.
ONCOGENE (2020)
Modeling Breast Cancer Using CRISPR-Cas9-Mediated Engineering of Human Breast Organoids
Johanna F. Dekkers et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2020)
Transcriptomic and cellular analyses of CRISPR/Cas9-mediated edition of FASN show inhibition of aggressive characteristics in breast cancer cells
Fernando Gonzalez-Salinas et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies
Devikala Gurusamy et al.
CANCER CELL (2020)
CRISPR/Cas: From Tumor Gene Editing to T Cell-Based Immunotherapy of Cancer
Mohammadreza Azangou-Khyavy et al.
FRONTIERS IN IMMUNOLOGY (2020)
CRISPR/Cas9-mediated mutagenesis to validate the synergy between PARP1 inhibition and chemotherapy in BRCA1-mutated breast cancer cells
Rachel L. Mintz et al.
BIOENGINEERING & TRANSLATIONAL MEDICINE (2020)
Identification of preexisting adaptive immunity to Cas9 proteins in humans
Carsten T. Charlesworth et al.
NATURE MEDICINE (2019)
Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System
Colette Moses et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2019)
Ultrasound microbubble-mediated CRISPR/Cas9 knockout of C-erbB-2 in HEC-1A cells
Junhong Cai et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2019)
Impact of CXCR4 and CXCR7 knockout by CRISPR/Cas9 on the function of triple-negative breast cancer cells
Meng Yang et al.
ONCOTARGETS AND THERAPY (2019)
Reprogrammable CRISPR/dCas9-based recruitment of DNMT1 for site-specific DNA demethylation and gene regulation
Anrui Lu et al.
CELL DISCOVERY (2019)
miR-23b and miR-27b are oncogenic microRNAs in breast cancer: evidence from a CRISPR/Cas9 deletion study
Bethany N. Hannafon et al.
BMC CANCER (2019)
Search-and-replace genome editing without double-strand breaks or donor DNA
Andrew V. Anzalone et al.
NATURE (2019)
Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity
Guangchuan Wang et al.
NATURE IMMUNOLOGY (2019)
mTOR kinase leads to PTEN-loss-induced cellular senescence by phosphorylating p53
Seung Hee Jung et al.
ONCOGENE (2019)
miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer
Deepak Parashar et al.
CELL REPORTS (2019)
Knockout Of BIRC5 Gene By CRISPR/Cas9 Induces Apoptosis And Inhibits Cell Proliferation In Leukemic Cell Lines, HL60 And KG1
Manizheh Narimani et al.
BLOOD AND LYMPHATIC CANCER-TARGETS AND THERAPY (2019)
In vivo genome editing via the HITI method as a tool for gene therapy
Keiichiro Suzuki et al.
JOURNAL OF HUMAN GENETICS (2018)
Immunity to CRISPR Cas9 and Cas12a therapeutics
Wei Leong Chew
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2018)
Blocking don't eat me signal of CD47-SIRPα in hematological malignancies, an in-depth review
Atlantis Russ et al.
BLOOD REVIEWS (2018)
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression
Yi-Zi Zheng et al.
CANCER RESEARCH (2018)
Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes
Lepakshi Ranjha et al.
CHROMOSOMA (2018)
Delivering CRISPR: a review of the challenges and approaches
Christopher A. Lino et al.
DRUG DELIVERY (2018)
Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis
Dongxin Zhao et al.
MOLECULAR CELL (2018)
Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1
Yinghua Zhu et al.
NATURE COMMUNICATIONS (2018)
Development of an integrated CRISPRi targeting ΔNp63 for treatment of squamous cell carcinoma
Masakazu Yoshida et al.
Oncotarget (2018)
DNA Unwinding Is the Primary Determinant of CRISPR-Cas9 Activity
Shanzhong Gong et al.
CELL REPORTS (2018)
Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism
Jurian Schuijers et al.
CELL REPORTS (2018)
Break Breast Cancer Addiction by CRISPR/Cas9 Genome Editing
Haitao Yang et al.
JOURNAL OF CANCER (2018)
Application of the CRISPR/Cas9 System to Drug Resistance in Breast Cancer
Yinnan Chen et al.
ADVANCED SCIENCE (2018)
Combination immunotherapy: Taking Cancer vaccines to the next Level
Jeremy M. Grenier et al.
FRONTIERS IN IMMUNOLOGY (2018)
Exposing cancer with CRISPR-Cas9: from genetic identification to clinical therapy
Ping Fan et al.
TRANSLATIONAL CANCER RESEARCH (2018)
Strategies for controlling CRISPR/Cas9 off-target effects and biological variations in mammalian genome editing experiments
Michelle L. Kimberland et al.
JOURNAL OF BIOTECHNOLOGY (2018)
TTK promotes mesenchymal signaling via multiple mechanisms in triple negative breast cancer
Jamie L. King et al.
ONCOGENESIS (2018)
Delivery systems of CRISPR/Cas9-based cancer gene therapy
Alessio Biagioni et al.
JOURNAL OF BIOLOGICAL ENGINEERING (2018)
CRISPR/Cas9 for Cancer Therapy: Hopes and Challenges
Marta Martinez-Lage et al.
BIOMEDICINES (2018)
Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer
Monica Alvarez-Fernandez et al.
CELL DEATH AND DIFFERENTIATION (2018)
mTOR signaling in skeletal development and disease
Jianquan Chen et al.
BONE RESEARCH (2018)
Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer
A. Harrod et al.
ONCOGENE (2017)
Genetic testing in women with breast cancer: implications for treatment
Robin Paterson et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2017)
Molecular Biomarkers for Prediction of Targeted Therapy Response in Metastatic Breast Cancer: Trick or Treat?
Angela Toss et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Metabolic shifts in residual breast cancer drive tumor recurrence
Kristina M. Havas et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
Justin Eyquem et al.
NATURE (2017)
Identification of essential genes for cancer immunotherapy
Shashank J. Patel et al.
NATURE (2017)
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
Julia Joung et al.
NATURE PROTOCOLS (2017)
The Chromatin Structure Differentially Impacts High-Specificity CRISPR-Cas9 Nuclease Strategies
Xiaoyu Chen et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2017)
Tumor cell-targeted delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGFA in osteosarcoma
Chao Liang et al.
BIOMATERIALS (2017)
Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion
Sisi Qin et al.
BREAST CANCER RESEARCH (2017)
Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models
Amir Bahreini et al.
BREAST CANCER RESEARCH (2017)
E3 Ubiquitin Ligase UBR5 Drives the Growth and Metastasis of Triple-Negative Breast Cancer
Liqiu Liao et al.
CANCER RESEARCH (2017)
CRISPR-mediated targeting of HER2 inhibits cell proliferation through a dominant negative mutation
Huajing Wang et al.
CANCER LETTERS (2017)
MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems
Tetsushi Sakuma et al.
NATURE PROTOCOLS (2016)
The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin
Yifan Wang et al.
CANCER RESEARCH (2016)
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects
Benjamin P. Kleinstiver et al.
NATURE (2016)
A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice
Yang Yang et al.
NATURE BIOTECHNOLOGY (2016)
Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells
Nirmala Jagadish et al.
TUMOR BIOLOGY (2016)
The association of PTEN hypermethylation and breast cancer: a meta-analysis
Shanshan Luo et al.
ONCOTARGETS AND THERAPY (2016)
CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter
Samrat Roy Choudhury et al.
ONCOTARGET (2016)
Overcoming doxorubicin resistance of cancer cells by Cas9-mediated gene disruption
Jong Seong Ha et al.
SCIENTIFIC REPORTS (2016)
FOXA1 defines cancer cell specificity
Gaihua Zhang et al.
SCIENCE ADVANCES (2016)
CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer
Yubao Wang et al.
CELL (2015)
Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy
Mario Giuliano et al.
CLINICAL CANCER RESEARCH (2015)
Noninvasive Detection of Activating Estrogen Receptor 1 (ESR1) Mutations in Estrogen Receptor-Positive Metastatic Breast Cancer
David S. Guttery et al.
CLINICAL CHEMISTRY (2015)
High-throughput functional genomics using CRISPR-Cas9
Ophir Shalem et al.
NATURE REVIEWS GENETICS (2015)
CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells
Norihiko Kawamura et al.
ONCOTARGET (2015)
Off-target Effects in CRISPR/Cas9-mediated Genome Engineering
Xiao-Hui Zhang et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2015)
Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-α protein levels and activity
M. J. Bolt et al.
ONCOGENE (2015)
A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression
Linghe Xi et al.
GENOME BIOLOGY (2015)
Optimizing sgRNA structure to improve CRISPR-Cas9 knockout efficiency
Ying Dang et al.
GENOME BIOLOGY (2015)
Emergence of Constitutively Active Estrogen Receptor-α Mutations in Pretreated Advanced Estrogen Receptor-Positive Breast Cancer
Rinath Jeselsohn et al.
CLINICAL CANCER RESEARCH (2014)
Estrogen Receptor Mutations in Breast Cancer-New Focus on an Old Target
Corrinne V. Segal et al.
CLINICAL CANCER RESEARCH (2014)
Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
Yanfang Fu et al.
NATURE BIOTECHNOLOGY (2014)
A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site
Mary Ann Hardwicke et al.
NATURE CHEMICAL BIOLOGY (2014)
Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9
Shota Nakade et al.
NATURE COMMUNICATIONS (2014)
Disruption of HPV16-E7 by CRISPR/Cas System Induces Apoptosis and Growth Inhibition in HPV16 Positive Human Cervical Cancer Cells
Zheng Hu et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013
A. Goldhirsch et al.
ANNALS OF ONCOLOGY (2013)
Relative and disease-free survival for breast cancer in relation to subtype: a population-based study
Pamela Minicozzi et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2013)
DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
NATURE BIOTECHNOLOGY (2013)
Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals
Monica Alvarez-Fernandez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Chromatin Sampling-An Emerging Perspective on Targeting Polycomb Repressor Proteins
Robert J. Klose et al.
PLOS GENETICS (2013)
FOXA1: a transcription factor with parallel functions in development and cancer
Gina M. Bernardo et al.
BIOSCIENCE REPORTS (2012)
New drugs for breast cancer subtypes: Targeting driver pathways to overcome resistance
Giuseppe Curigliano
CANCER TREATMENT REVIEWS (2012)
The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications
Mark P. Chao et al.
CURRENT OPINION IN IMMUNOLOGY (2012)
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
Christina Curtis et al.
NATURE (2012)
Triple-negative breast cancer and PTEN (phosphatase and tensin homologue) loss are predictors of BRCA1 germline mutations in women with early-onset and familial breast cancer, but not in women with isolated late-onset breast cancer
Sze-Yee Phuah et al.
BREAST CANCER RESEARCH (2012)
Antiestrogens and Their Therapeutic Applications in Breast Cancer and Other Diseases
Simak Ali et al.
ANNUAL REVIEW OF MEDICINE, VOL 62, 2011 (2011)
Phosphatases: providing safe passage through mitotic exit
Claudia Wurzenberger et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A
Aicha Gharbi-Ayachi et al.
SCIENCE (2010)
PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells
Anne-Marie Bleau et al.
CELL STEM CELL (2009)
FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene
Tao Zuo et al.
CELL (2007)
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development
Jennifer M. Burns et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)