Cancer disparities in the context of rurality: risk factors and screening across various US rural classification codes

Purpose Prior cancer research is limited by inconsistencies in defining rurality. The purpose of this study was to describe the prevalence of cancer risk factors and cancer screening behaviors across various county-based rural classification codes, including measures reflecting a continuum, to inform our understanding of cancer disparities according to the extent of rurality. Methods Using an ecological cross-sectional design, we examined differences in cancer risk factors and cancer screening behaviors from the Behavioral Risk Factor Surveillance System and National Health Interview Survey (2008-2013) across rural counties and between rural and urban counties using four rural-urban classification codes for counties and county-equivalents in 2013: U.S. Office of Management and Budget, National Center for Health Statistics, USDA Economic Research Service's rural-urban continuum codes, and Urban Influence Codes. Results Although a rural-to-urban gradient was not consistently evident across all classification codes, the prevalence of smoking, obesity, physical inactivity, and binge alcohol use increased (all p(trend) < 0.03), while colorectal, cervical and breast cancer screening decreased (all p(trend) < 0.001) with increasing rurality. Differences in the prevalence of risk factors and screening behaviors across rural areas were greater than differences between rural and urban counties for obesity (2.4% vs. 1.5%), physical activity (2.9% vs. 2.5%), binge alcohol use (3.4% vs. 0.4%), cervical cancer screening (6.8% vs. 4.0%), and colorectal cancer screening (4.4% vs. 3.8%). Conclusions Rural cancer disparities persist across multiple rural-urban classification codes, with marked variation in cancer risk factors and screening evident within rural regions. Focusing only on a rural-urban dichotomy may not sufficiently capture subpopulations of rural residents at greater risk for cancer and cancer-related mortality.

Automated summary

This study aimed to describe the prevalence of cancer risk factors and cancer screening behaviors across different rural classification codes. The results showed that as the rurality increased, the prevalence of smoking, obesity, physical inactivity, and binge alcohol use increased, while colorectal, cervical, and breast cancer screening rates decreased. The differences in risk factors and screening behaviors within rural regions were greater than the differences between rural and urban areas. This suggests that focusing solely on the rural-urban dichotomy may not adequately capture subpopulations of rural residents at higher risk for cancer and cancer-related mortality.