4.7 Review

Recent insights into the effects of metabolism on breast cancer cell dormancy

Related references

Note: Only part of the references are listed.
Review Oncology

The lingering mysteries of metastatic recurrence in breast cancer

Alessandra I. Riggio et al.

Summary: This review provides an overview of the key factors influencing metastatic recurrence in breast cancer, highlighting critical unanswered questions that need to be addressed.

BRITISH JOURNAL OF CANCER (2021)

Article Oncology

Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group

Torsten O. Nielsen et al.

Summary: Ki67 immunohistochemistry (IHC) is commonly used in breast cancer as a proliferation marker, but its analytical validity has been questioned. The International Ki67 in Breast Cancer Working Group (IKWG) recommends careful preanalytical handling, adoption of a standardized visual scoring method, and participation in quality assurance and quality control programs. Clinical utility of Ki67 IHC in breast cancer care is currently limited to prognosis assessment in stage I or II breast cancer.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2021)

Review Endocrinology & Metabolism

Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics

Pauline Morigny et al.

Summary: White adipocyte metabolism plays a crucial role in systemic metabolism regulation and is often disrupted in conditions like cancer and type 2 diabetes mellitus. This review provides an overview of lipid metabolism in white adipocytes and discusses how these pathways can serve as therapeutic targets in metabolic disorders.

NATURE REVIEWS ENDOCRINOLOGY (2021)

Review Oncology

High ATP Production Fuels Cancer Drug Resistance and Metastasis: Implications for Mitochondrial ATP Depletion Therapy

Marco Fiorillo et al.

Summary: The study suggests that high mitochondrial ATP production is a new therapeutic target for cancer treatment, isolating metabolically fit cancer cells with enhanced stem-like properties and invasive abilities. By regulating mitochondrial ATP-synthase, prevention of metastasis in cancer cells is possible.

FRONTIERS IN ONCOLOGY (2021)

Review Oncology

Targeting mTOR and Glycolysis in HER2-Positive Breast Cancer

Ryan W. Holloway et al.

Summary: Approximately one third of all breast cancers are classified as HER2-positive, with a higher risk of recurrence. Elevated HER2 levels lead to increased mTOR pathway activity and cancer cell growth. Combination therapies show improved clinical outcomes but also come with more toxic effects and a higher risk of recurrence.

CANCERS (2021)

Review Cell Biology

The role of glutaminase in cancer

Brendah K. Masisi et al.

HISTOPATHOLOGY (2020)

Review Cell Biology

In vitro Models of Breast Cancer Metastatic Dormancy

Marco Montagner et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Article Oncology

AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells

Riley A. Hampsch et al.

CLINICAL CANCER RESEARCH (2020)

Review Biochemistry & Molecular Biology

The force awakens: metastatic dormant cancer cells

So-Yeon Park et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2020)

Article Biochemistry & Molecular Biology

Targeting disseminated estrogen-receptor-positive breast cancer cells in bone marrow

Johanna M. Buschhaus et al.

ONCOGENE (2020)

Article Oncology

MicroRNAs Regulate Metabolic Phenotypes During Multicellular Tumor Spheroids Progression

Erick Andres Mucino-Olmos et al.

FRONTIERS IN ONCOLOGY (2020)

Article Cell Biology

Nrf2 promotes breast cancer cell migration via up-regulation of G6PD/HIF-1α/Notch1 axis

Hong-Sheng Zhang et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)

Review Cell Biology

Mutational anc Anticenic Lancsca Tumor Procression anc Cancer Immunotheraoy

Ilio Vitale et al.

TRENDS IN CELL BIOLOGY (2019)

Review Endocrinology & Metabolism

Breast Cancer Dormancy in Bone

Miranda E. Clements et al.

CURRENT OSTEOPOROSIS REPORTS (2019)

Article Multidisciplinary Sciences

Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression

Alyssa La Belle Flynn et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

UGCG influences glutamine metabolism of breast cancer cells

Nina Schoemel et al.

SCIENTIFIC REPORTS (2019)

Review Oncology

Targeting Autophagy in Cancer

Angelique V. Onorati et al.

CANCER (2018)

Review Biochemistry & Molecular Biology

Mitochondrial dynamics: overview of molecular mechanisms

Lisa Tilokani et al.

MITOCHONDRIAL DISEASES (2018)

Article Multidisciplinary Sciences

Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence

Laura Vera-Ramirez et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Four Key Steps Control Glycolytic Flux in Mammalian Cells

Lukas Bahati Tanner et al.

CELL SYSTEMS (2018)

Review Biochemistry & Molecular Biology

The Roles of Autophagy in Cancer

Chul Won Yun et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Biochemistry & Molecular Biology

Metastatic Breast Cancer Cells Enter Into Dormant State and Express Cancer Stem Cells Phenotype Under Chronic Hypoxia

Alessandra Carcereri de Prati et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2017)

Article Medicine, Research & Experimental

Metabolic shifts in residual breast cancer drive tumor recurrence

Kristina M. Havas et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Article Medicine, General & Internal

20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

Hongchao Pan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Oncology

Mechanisms governing metastatic dormancy in breast cancer

Juergen Dittmer

SEMINARS IN CANCER BIOLOGY (2017)

Review Biochemistry & Molecular Biology

Roles of PFKFB3 in cancer

Linlin Shi et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2017)

Article Multidisciplinary Sciences

Early dissemination seeds metastasis in breast cancer

Hedayatollah Hosseini et al.

NATURE (2016)

Article Multidisciplinary Sciences

ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles

Mark A. Rider et al.

SCIENTIFIC REPORTS (2016)

Review Obstetrics & Gynecology

A historic and scientific review of breast cancer: The next global healthcare challenge

Sven Becker

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2015)

Review Biotechnology & Applied Microbiology

Metabolic Regulation of Mesenchymal Stem Cell in Expansion and Therapeutic Application

Yijun Liu et al.

BIOTECHNOLOGY PROGRESS (2015)

Article Computer Science, Information Systems

Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality

Hua Xu et al.

JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION (2015)

Review Medicine, General & Internal

PI3K/AKT signaling pathway and cancer: an updated review

Miriam Martini et al.

ANNALS OF MEDICINE (2014)

Review Oncology

Treatment of HER2-positive breast cancer

Maria Cristina Figueroa-Magalhaes et al.

BREAST (2014)

Review Endocrinology & Metabolism

Autophagy-a key player in cellular and body metabolism

Kook Hwan Kim et al.

NATURE REVIEWS ENDOCRINOLOGY (2014)

Article Radiology, Nuclear Medicine & Medical Imaging

Molecular Classification of Infiltrating Breast Cancer: Toward Personalized Therapy

Isabelle Trop et al.

RADIOGRAPHICS (2014)

Review Oncology

AMPK: A Contextual Oncogene or Tumor Suppressor?

Jiyong Liang et al.

CANCER RESEARCH (2013)

Review Endocrinology & Metabolism

Autophagy: a targetable linchpin of cancer cell metabolism

Robert D. Leone et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2013)

Review Medicine, Research & Experimental

Cellular and molecular mechanisms of metformin: an overview

Benoit Viollet et al.

CLINICAL SCIENCE (2012)

Article Multidisciplinary Sciences

Comprehensive molecular portraits of human breast tumours

Daniel C. Koboldt et al.

NATURE (2012)

Review Cell Biology

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

Sophia Y. Lunt et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Review Cell Biology

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

Maria M. Mihaylova et al.

NATURE CELL BIOLOGY (2011)

Review Oncology

Otto Warburg's contributions to current concepts of cancer metabolism

Willem H. Koppenol et al.

NATURE REVIEWS CANCER (2011)

Review Multidisciplinary Sciences

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

Matthew G. Vander Heiden et al.

SCIENCE (2009)

Article Oncology

Systemic spread is an early step in breast cancer

Yves Huesemann et al.

CANCER CELL (2008)

Review Biochemistry & Molecular Biology

Energy metabolism in tumor cells

Rafael Moreno-Sanchez et al.

FEBS JOURNAL (2007)

Review Biochemistry & Molecular Biology

Rheostat control of gene expression by metabolites

Andreas G. Ladurner

MOLECULAR CELL (2006)

Article Medicine, General & Internal

Targeting the ERK signaling pathway in cancer therapy

M Kohno et al.

ANNALS OF MEDICINE (2006)

Article Oncology

Circulating tumor cells in patients with breast cancer dormancy

SD Meng et al.

CLINICAL CANCER RESEARCH (2004)

Review Biochemistry & Molecular Biology

The hallmarks of cancer

D Hanahan et al.