4.5 Article

Antioxidant and chemoprotective peptides from simulated gastrointestinal digested (SGID) protein hydrolysate of Pyropia yezoensis against acetaminophen-induced HepG2 cells

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Seaweed-Derived Proteins and Peptides: Promising Marine Bioactives

Javier Echave et al.

Summary: Seaweeds, a typical food in East-Asian cuisine, have been attributed with several beneficial health effects. Seaweed proteins contain various enzymes, glycoproteins, cell wall-attached proteins, red algae phycobiliproteins, lectins, peptides, or mycosporine-like amino acids, which show significant antioxidant, antimicrobial, anti-inflammatory, and other bioactivities. Understanding seaweed proteins and derived molecules is important for potential nutraceutical, cosmetic, or pharmaceutical applications.

ANTIOXIDANTS (2022)

Review Pharmacology & Pharmacy

Targeting innate immune responses to attenuate acetaminophen-induced hepatotoxicity

Jincheng Wang et al.

Summary: Acetaminophen (APAP) hepatotoxicity is a significant cause of acute liver failure, and immune cells play important roles in its pathogenesis by inducing inflammation to exacerbate liver toxicity and promoting liver regeneration by removing dead cells and debris.

BIOCHEMICAL PHARMACOLOGY (2022)

Article Biotechnology & Applied Microbiology

Biogenic preparation and characterization ofPyropia yezoensissilver nanoparticles (P.yAgNPs) and their antibacterial activity againstPseudomonas aeruginosa

Selvakumari Ulagesan et al.

Summary: Marine algae play crucial roles in various fields like medicine and agriculture, with biosynthesized silver nanoparticles showing effective antibacterial properties, especially against Gram-negative bacteria. The study suggests that Pyropia yezoensis silver nanoparticles may be beneficial in treating bacterial infections.

BIOPROCESS AND BIOSYSTEMS ENGINEERING (2021)

Article Biochemistry & Molecular Biology

Extraction and Purification of R-Phycoerythrin Alpha Subunit from the Marine Red Algae Pyropia Yezoensis and Its Biological Activities

Selvakumari Ulagesan et al.

Summary: In this study, phycoerythrin was extracted and purified from Pyropia yezoensis, showing significant antioxidant activity and cytotoxicity against HepG2 cells. The pigment had a typical spectrum of R-phycoerythrin and a molecular mass of 17.97 kDa, with a 100% sequence similarity with the R-phycoerythrin alpha subunit of Pyropia yezoensis.

MOLECULES (2021)

Review Biochemistry & Molecular Biology

A Review on Health-Promoting, Biological, and Functional Aspects of Bioactive Peptides in Food Applications

Seyed Hadi Peighambardoust et al.

Summary: Food-derived bioactive peptides are specific protein fractions that show broad applications in cosmetics, food additives, nutraceuticals, and pharmaceuticals. They have biological properties such as antihypertensive, antioxidative, antiobesity, and hypocholesterolemic effects, as well as functional properties such as water holding capacity, solubility, emulsifying, and foaming abilities. These peptides can be extracted from various foods and used as ingredients to formulate health-promoting foods, offering the possibility to develop novel healthy food products.

BIOMOLECULES (2021)

Article Food Science & Technology

Identification and characterization of antioxidant peptides obtained from the bioaccessible fraction of α-lactalbumin hydrolysate

Jessica Baez et al.

Summary: The study demonstrated a significant increase in antioxidant activity of alpha-lactalbumin after enzymatic treatment with alcalase, which further improved after simulating gastrointestinal digestion. Three novel bioaccessible peptides with antioxidant capacity were identified from the gastrointestinal digest, suggesting the potential of alpha-lactalbumin hydrolysate as an antioxidant ingredient in functional foods.

JOURNAL OF FOOD SCIENCE (2021)

Article Medicine, Research & Experimental

PYP1-4 peptide from Pyropia yezoensis protects against acetaminophen-induced hepatotoxicity in HepG2 cells

In-Hye Kim et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2020)

Article Biochemical Research Methods

Peptidyl-prolyl isomerase and the biological activities of recombinant protein cyclophilin from Pyropia yezoensis (PyCyp)

Selvakumari Ulagesan et al.

PROTEIN EXPRESSION AND PURIFICATION (2020)

Article Food Science & Technology

Effect of in vitro simulated gastrointestinal digestion on the antioxidant activity of the red seaweed Porphyra dioica

Filipa B. Pimentel et al.

FOOD RESEARCH INTERNATIONAL (2020)

Review Gastroenterology & Hepatology

COVID-19 and Liver Dysfunction: Current Insights and Emergent Therapeutic Strategies

Gong Feng et al.

JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY (2020)

Article Biochemistry & Molecular Biology

Increase in anti-inflammatory activities of radical-degraded porphyrans isolated from discolored nori (Pyropia yezoensis)

Ayana Yanagido et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Food Science & Technology

Changes in the Antioxidant Potential of Nori Sheets During in vitro Digestion with Pepsin

Indumathi Parimelazhagan et al.

JOURNAL OF AQUATIC FOOD PRODUCT TECHNOLOGY (2017)

Article Food Science & Technology

Fractionation and identification of antioxidant peptides from an enzymatically hydrolysed Palmaria palmata protein isolate

Padraigin A. Harnedy et al.

FOOD RESEARCH INTERNATIONAL (2017)

Article Pharmacology & Pharmacy

Astaxanthin conjugated polypyrrole nanoparticles as a multimodal agent for photo-based therapy and imaging

Subramaniyan Bharathiraja et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

Article Biochemistry & Molecular Biology

In Vitro Photodynamic Effect of Phycocyanin against Breast Cancer Cells

Subramaniyan Bharathiraja et al.

MOLECULES (2016)

Review Gastroenterology & Hepatology

Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update

Eric Yoon et al.

JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY (2016)

Article Medicine, Research & Experimental

Bioactive peptide from Pyropia yezoensis and its anti-inflammatory activities

Hyun-Ah Lee et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2015)

Article Medicine, Research & Experimental

Chemoprotective effects of a recombinant protein from Pyropia yezoensis and synthetic peptide against acetaminophen-induced Chang liver cell death

Youn Hee Choi et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2015)

Article Food Science & Technology

Chemical composition, nutritional and antioxidant properties of the red edible seaweed Porphyra columbina

Raul E. Cian et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2014)

Article Pharmacology & Pharmacy

Mechanisms of acetaminophen-induced cell death in primary human hepatocytes

Yuchao Xie et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)

Review Gastroenterology & Hepatology

Review article: herbal and dietary supplement hepatotoxicity

C. Bunchorntavakul et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2013)

Article Agronomy

Nutrient and heavy metal content of edible seaweeds in New Zealand

J. L. Smith et al.

NEW ZEALAND JOURNAL OF CROP AND HORTICULTURAL SCIENCE (2010)

Article Chemistry, Applied

ORAC and TEAC assays comparison to measure the antioxidant capacity of food products

Ana Zulueta et al.

FOOD CHEMISTRY (2009)

Article Food Science & Technology

New antioxidant protein in seaweed (Porphyra yezoensis Ueda)

Toshiyuki Toyosaki et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2009)

Article Chemistry, Applied

Amino acids, fatty acids, and dietary fibre in edible seaweed products

Christine Dawczynski et al.

FOOD CHEMISTRY (2007)

Article Agriculture, Multidisciplinary

Antioxidant properties of a radical-scavenging peptide purified from enzymatically prepared fish skin gelatin hydrolysate

E Mendis et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)

Article Pharmacology & Pharmacy

Interaction of enkephalins with oxyradicals

M Fontana et al.

BIOCHEMICAL PHARMACOLOGY (2001)