Structurally Modified Plant Viruses and Bacteriophages with Helical Structure. Properties and Applications

Structurally modified virus particles can be obtained from the rod-shaped or filamentous virions of plant viruses and bacteriophages by thermal or chemical treatment. They have recently attracted attention of the researchers as promising biogenic platforms for the development of new biotechnologies. This review presents data on preparation, structure, and properties of the structurally modified virus particles. In addition, their biosafety for animals is considered, as well as the areas of application of such particles in biomedicine. A separate section is devoted to one of the most relevant and promising areas for the use of structurally modified plant viruses - design of vaccine candidates based on them.

Automated summary

This review focuses on the preparation, structure, properties, and applications of structurally modified virus particles, which have attracted attention as promising biogenic platforms for new biotechnologies. The biosafety of these particles for animals is considered, and the design of vaccine candidates based on structurally modified plant viruses is discussed as a relevant and promising area.