Chemical constituents from Machilus salicina Hance

This first phytochemical investigation on the leaves and stems of Machilus salicina Hance led to the isolation of thirteen compounds, including lupeol (1), betulin (2), meso-dihydroguaiaretic acid (3), isoguaiacin (4), nectandrin B (5), kaempferol (6), taxifolin (7), (2R,3R)-3-hydroxy-5,7-dimethoxy-3 & PRIME;,4 & PRIME;-methylenedioxy-flavan (8), cinnacassin N (9), 1H-indole-3-carboxaldehyde (10), 3-[p-hydroxyphenyl]-propionic acid amide (11), N-ace-tyltyramine (12), and N-cis-feruloyltyramine (13). The types of the compounds involved lupane triterpenoids (1 and 2), lignans (3-5), flavonoids (6-8), 1,3-diarylpropanoid (9), indole (10) and amides (11-13). Among them, compounds 1, 2 and 9-12 had never been isolated from the genus Machilus. The chemotaxonomic significance of these compounds was also summarized.

Automated summary

The first phytochemical investigation of Machilus salicina Hance resulted in the isolation of thirteen compounds, including some that had never been found in the Machilus genus before. These compounds belong to various chemical classes and have significant chemotaxonomic implications.