Synthesis of odorants in flow and their applications in perfumery

Continuous flow technology is a key technology for sustainable manufacturing with numerous applications for the synthesis of fine chemicals. In recent years, the preparation of odorants utilizing the advantages of flow reactors received growing attention. In this review, we give an overview of selected methods for the synthesis of odorants in flow, including heterogeneously catalyzed reac-tions, gas reactions, and photochemical C???H functionalization processes. After a brief introduction on types of odorants, the presented odorant syntheses are ordered according to the main odor families ???fruity???, ???green???, ???marine???, ???floral???, ???spicy???, ???woody???, ???ambery???, and ???musky??? and their use and importance for perfumery is briefly discussed.

Automated summary

This review provides an overview of selected methods for synthesizing odorants utilizing continuous flow technology, categorizing them by main odor families. The importance and application of odorants in perfumery are briefly discussed.