Is there a role of epigenetics in gut microbiome and neurological disorders?

Cross-talk between gut microbiota and the nervous system in the pathophysiology of neurological diseases has become a recent focus of interest. The underlying mechanisms are complex, and we suggest that they might involve gut bacterial metabolite-induced epigenetic modulations of neurodegenerative disorders. Advances in epigenetic techniques could provide the key to understanding the epigenetics of the gut-brain axis.

Automated summary

The interaction between gut microbiota and the nervous system plays a crucial role in the pathophysiology of neurological diseases, possibly through gut bacterial metabolite-induced epigenetic modulations of neurodegenerative disorders. Advances in epigenetic techniques hold promise for unraveling the epigenetic mechanisms of the gut-brain axis.