Incidence and Relative Burden of Surgical Site Infections in Children Undergoing Nonemergent Surgery Implications for Performance Benchmarking and Prioritization of Prevention Efforts

Objective:To establish surgical site infection (SSI) performance benchmarks in pediatric surgery and to develop a prioritization framework for SSI prevention based on procedure-level SSI burden. Background:Contemporary epidemiology of SSI rates and event burden in elective pediatric surgery remain poorly characterized. Methods:Multicenter analysis using sampled SSI data from 90 hospitals participating in NSQIP-Pediatric and procedural volume data from the Pediatric Health Information System (PHIS) database. Procedure-level incisional and organ space SSI (OSI) rates for 17 elective procedure groups were calculated from NSQIP-Pediatric data and estimates of procedure-level SSI burden were extrapolated using procedural volume data. The relative contribution of each procedure to the cumulative sum of SSI events from all procedures was used as a prioritization framework. Results:A total of 11,689 nonemergent procedures were included. The highest incisional SSI rates were associated with gastrostomy closure (4.1%), small bowel procedures (4.0%), and gastrostomy (3.7%), while the highest OSI rates were associated with esophageal atresia/tracheoesophageal fistula repair (8.1%), colorectal procedures (1.8%), and small bowel procedures (1.5%). 66.1% of the cumulative incisional SSI burden from all procedures were attributable to 3 procedure groups (gastrostomy: 27.5%, small bowel: 22.9%, colorectal: 15.7%), and 72.8% of all OSI events were similarly attributable to 3 procedure groups (small bowel: 28.5%, colorectal: 26.0%, esophageal atresia/tracheoesophageal fistula repair: 18.4%). Conclusions:A small number of procedures account for a disproportionate burden of SSIs in pediatric surgery. The results of this analysis can be used as a prioritization framework for refocusing SSI prevention efforts where they are needed most.

Automated summary

This study aimed to establish performance benchmarks for surgical site infection (SSI) in pediatric surgery and develop a prioritization framework for SSI prevention based on procedure-level burden. The analysis of data from 90 hospitals participating in NSQIP-Pediatric and procedural volume data from the PHIS database revealed that a small number of procedures account for a disproportionate burden of SSIs in pediatric surgery. The findings can be used to prioritize SSI prevention efforts.