Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 61, Issue 34, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.202208678
Keywords
Dynamics; Real-Time Heterogeneity; Self-Assembly; Super-Resolution Imaging
Categories
Funding
- National Natural Science Foundation of China [22078314, 21878286, 21908216]
- Dalian Institute of Chemical Physics [DICPI202142, DICPI201938, DICPZZBS201805]
Ask authors/readers for more resources
By using single-molecule localization microscopy, we visualized the dynamic process of benzyl-naphthalimide dyes in real time and examined their internal structure. We found that the growth process of these assemblies exhibited highly heterogeneous dynamics, with different growth rates at different locations.
The visualization of self-assembled structure and dynamics at the molecular level has become a powerful method to understand structure-function relationships of self-assembly. Herein, we in situ real-time imaged the dynamic process of benzyl-naphthalimide dyes at the nanoscale and inspected their internal structure with minimum 2.8 nm localization accuracy through single-molecule localization microscopy (SMLM) imaging. We monitored the growth process of three different assemblies in situ, which possessed highly heterogeneous dynamics with different shapes and growth rates. Furthermore, diverse growth rates were also found at different sites in the same assembly. These results highlight the application of super-resolution microscopy techniques for real-time visualization of internal assembled structure and dynamics in situ.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available